* "NUNS?! NUNS think I'm a bad mother?!"
* Debbie reads aloud from a ''WeeklyWorldNews''-type tabloid magazine: "Oh, look! A 99-year-old woman gave birth to twin 3-headed cows! And the father is a chicken!"
* Nigel tries to edit the newest footage himself... resulting in him accidentally having a warthog lip-synch his introduction.
-->'''Nigel''': The warthog is talking like me! ''(chuckles)''
* Donny.
* Come on, say it:
-->[[MemeticMutation I'll do]] ''[[MemeticMutation this]]''[[MemeticMutation ...with my]] ''[[MemeticMutation hands]]''[[MemeticMutation ! Blaaaaaaaaarghghghghghgh!]]
* From the first episode:
-->Mount Kilamanjaro, Africa's highest peak. And roaming in its shadow, the king of beasts, the lion, known to local tribesmen as--ACK OOK ICH ACH BLUAH!
* Anytime Darwin's [[DeadpanSnarker snarky side]] shows.
* Nigel's line in in 'Reef Grief.' "We seem to be faced with a ''fascinating'' lack of options!"
* Nigel's attempt at throat-singing at the end of 'Horse Sense.'
* In 'Bogged Down' Eliza and Darwin are being threatened by mysterious creatures who later turn out to be flying lemurs. As Eliza leaves them alone they sigh in relief only for Darwin to scare them off with a sudden loud evil laugh.
!!The Movie
* When Darwin sneaks into Eliza's bag and causes a food fight in the lunch room. He is therefore forced to be left in the horse's barn.
-->'''Darwin''': Where's the bathroom?\\
'''Thunder''': You're ''standing on it!''\\
''(view to Darwin's feet sinking in horse manure)''\\
'''Darwin''': AAAAH!!!!
** Later Grandmumsy Cordelia and Grandpa Ratcliff report to Debbie that Eliza escaped from boarding school. Debbie's response?
-->'''Debbie''': Wait a minute! Hold on...[[ComicallyMissingThePoint THE MONKEY GOT TO GO TO LONDON?!]]

* "Excuse me while I go find a container for my joy."
* When Debbie runs into the natives, who send one of them named Boko as her guide. While Debbie tries to tell Boko he can't come, Boko notices a ''large snake approaching her'', and ''fights it'', while Debbie, ''utterly oblivious'', babbles on and on as Boko continues fighting the snake, then tosses it aside.
* This gem as Nigel and Mary Ann leave Debbie with Donnie.
-->'''Nigel''': We'll be gone until after the eclipse. Will you be all right with Donnie?\\
'''Debbie''': [[SarcasmMode Are you kidding? This'll be the highlight of my young life!]]\\
'''Nigel''': That's the spirit, poodles!\\
'''Debbie''': [[LampshadeHanging Dad, have you completely lost your ability to recognize sarcasm]]?\\
'''Nigel''': [[SelfDeprecation I'm not sure I ever had it, Deborah]].