Rincewind trying to swear at Twoflower in Trobian, which doesn't really have profanities:
You little [such a one who, while wearing a copper nose ring, stands in the bath atop Mt. Raruaruaha during a thunderstorm and shouts that the goddess of lightning has the face of a diseased uloruaha root]!!
Rincewind working out the meaning of several words Twoflower uses, like "tourist":
Twoflower was a tourist, the first ever seen on the Discworld. Tourist, Rincewind had decided, meant "idiot".
"Some pirates achieved immortality by grand deeds of cruelty or derring-do. Some achieved immortality by amassing great amounts of wealth. But the Captain had long ago decided that he would, on the whole, prefer to achieve immortality by not dying."
The competing theories about the nature of the universe, especially with the Genius Bonus that the support for them is switched from our world: Scientists support the Steady State Theory while religious types support the Big Bang Theory.
In the film, when Rincewind and Twoflower are meeting for the first time they are discussing the Counterweight Continent.
Rincewind: But the legend says it's made of gold.
Twoflower: Well, it's not made of gold. Gold is just a really common metal there.
Rincewind: You might like to keep that to ourselves.
(Rincewind turns around and sees Broadman several inches away from his face)
Also in the film, Rincewind is trying to drag Twoflower out of Death's house. Then we get this exchange:
Twoflower: Amazing! I've never been at Death's door before!
(Rincewind punches him across the face)
In the film, Rincewind flipping off Blind Hugh after succeeding in communicating with Twoflower.