Moments that put the "Funny" in "Strange. Funny. Heartrending." And sometimes, [[SurrealHumor "Strange" as well]].
* In Ellay, a woman offers to buy Ninten a drink. Accepting results in [[spoiler:Ninten and friends getting arrested for underage drinking.]]
* "Groucho said 'Hello,' then just walked away. Don't know why, but Ninten's EXP increased."
** Also from Magicant, the cat who swims on land.
** One of Queen Mary's guards asks for the answer to a riddle. Using Telepathy on him reveals he answer, and he reveals that he hadn't come up with a riddle yet.
* When you CHECK an enemy, some of the comments are pretty hilarious, the [[BearsAreBadNews bear]] enemies, for example, their comments are references to ''Literature/{{Goldilocks}}'':
** '''Bear:''' OFFENSE 42, DEFENSE 64. Somebody ate his porridge, and he isn't too happy about it.
** '''Polar Bear:''' OFFENSE 52, DEFENSE 180. His chair was broken, and he isn't very happy!
** '''Grizzly Bear:''' OFFENSE 160, DEFENSE 340. If you must sleep, don't borrow his bed!
* Other kind of enemies also have pretty funny comments:
** '''Watcher:''' OFFENSE 16, DEFENSE 24. This enemy's face is the easiest to draw.
** '''Titanian:''' OFFENSE 100, DEFENSE 420. [[DemonicSpiders If you can beat it,]] [[LampshadeHanging this is great!]]
** '''Dust Ball:''' OFFENSE 40, DEFENSE 120. AHH-choooo!
** '''Crow:''' OFFENSE 8, DEFENSE 12. [[BanditMook Watch your wallet and count your change. He's a thief.]]

* Every single time the traveling photo man appears. "Say fuzzy pickles!"
** Not to mention the time when the photographer drops into Brick Road's first maze just after Jeff reads the sign warning "Watch out for falling objects".
* The mere fact that there are bug enemies in this game. No, not BigCreepyCrawlies, just regular-sized ants, roaches, slugs, and the like. They even show up on the overworld as just a couple of black pixels. The fact that, at the time of meeting them, [[LethalJokeCharacter they're actually a threat]] doesn't hurt the humor value any, and it becomes more hilarious when you get strong enough to one-shot these encounters (apparently Ness just realized he could step on them).
* The Brick Road dungeon, and later Dungeon Man, for their constant lampshade hanging.
* The NPC in the Chaos Theater who tells you he farted.
* Some of the GettingCrapPastTheRadar quotes are worth a good laugh:
-->You will be gone, and you'll be burning in... well, you'll go to heaven![[note]]In the original Japanese version, he says "Die and go to hell– No, to heaven!"[[/note]]
-->Blue, blue. You strange, unmasked fellow. Don't go to heaven![[note]]Contrary to popular belief, one of the cultists actually says "Don't go to heaven!" in the original Japanese version.[[/note]]
* If you want a good old-fashioned laugh, buy the house in Onett and check in the drawer.
* Mr Spoon attempting to get on stage with Venus, only to be dragged off by security.
* The dungeon of five giant moles who ''all'' tell you they're the third strongest.
* Moonside. [[AcidTripDimension All of it]].
* Giygas. To some, [[NightmareFuel he's horrifying]]. To others, he's so over the top and cliche (or just plain strange to the point of SurrealHumor) that [[NightmareRetardant he loses all scariness factor]] and [[NarmCharm becomes one of, if not the funniest part of the game.]]
** Especially prevalent is the infamous [[SayMyName "NESS NESS NESS NESS NESS NESS NESS NESS NESS NESS NESS"]] line; [[HelloInsertNameHere abusing the name feature for Ness]] can turn the line into a [[InherentlyFunnyWords laugh]] [[ClusterFBomb riot.]]
** NightmareRetardant supreme, coming up. Take a look at Giygas's conceptual English name. [[ It's too good to spoil.]]

* The most depressed video game enemy in history, [[ the Negative Man]]. A ZeroEffortBoss, Negative Man does almost nothing but moan and cry that he's going to lose. He actually can attack, but he does it so rarely that many players never see him attack at all. And even then, the attack is pathetically weak. It's funny in a BlackComedy kind of way.
* In Chapter 3, Wess, accidentally nudging the remote to Salsa's shock collar and Salsa straight-up ''lunging'' at it, stamping the pavement with it.
* The page quote for DirtyOldMan.
-->'''Mike:''' I can't keep burdening Lisa forever, but I do have a Happy Box and nice-bodied girls like Nan and Linda to keep me company, so I'm pretty happy in my own way. Nyahahahaha!\\
'''Linda:''' I'm sorry, Mike, but that's called sexual harassment these days.\\
'''Mike:''' ...This is a hard world we live in now. How disappointing.
* [[ Wess Dance!]] It's also possible to replace Wess in that scene with several other characters, but apart from Kumatora, they're not animated to do the dance, so they end up doing something weird. In particular, Lucas appears to be ''mooning'' the door.
** The best part is that this makes the door ''laugh'', allowing you through.
-->"Don't look, now! [[SuspiciouslySpecificDenial I'm not going to stick my butt out or anything like that, though.]]"
* [[TalkingWithSigns "Your fly's open! XYZ!"]] Cue Lucas' [[LuminescentBlush reaction]], then...
** "You're much manlier now!"
** Potentially gets even funnier when you take into account that this sign appears near the very end of the game. [[FridgeLogic Exactly how long has Lucas' fly been open?]]
** Later in the next challenge: "Your fly's not open! Don't worry about it!"
* On some occasions, either a lady or an old man will inexplicably appear in a hot spring. And they can appear ''anywhere.'' Even in the Chimera Lab, where only Pigmasks should have access. And what they say makes it funnier.
--> '''Old Man''': Yes?
--> '''Lady''': Cross gender bathing?
* Some of the enemy Chimera designs are bizarre enough to be funny. Such as [[ the Ostrelephant]], and its entry in the [[MonsterCompendium Battle Memory]]:
-->"[[FridgeLogic Is the long part its trunk or its neck? How does it bathe itself?]] An utterly mysterious Chimera."
* Chapter 8. The [[spoiler:Empire Porky]] Building. The ''toilet dungeon.''
** And of course the Men's Room Sign enemy. Who inexplicably knows PK Starstorm.
* Roaming the highways in Chapter 7 ...on an animate coffee table.
** An animate coffee table shaped like a Mr. Saturn that whinnies like a horse.
* [[ Kumatora is rather... ''insistent'' that Lucas and Boney take a shower.]]
* This bit in Chapter 2, when Kumatora accidentally triggers a trapdoor that sends herself, Duster and Wess plummeting down a pit.
-->'''Wess''': PRINCESSSSSSSSS!!!\\
'''Kumatora''': My bad.
* At one point in Osohe Castle in Chapter 2, Duster is required to drop a heavy ball from a statue onto a cracked spot on the floor. Dashing into the statue from the opposite side will allow Duster to continue as normal. Dashing into it from the side of the cracked floor, on the other hand, [[ causes Duster to get smooshed]], resulting in a GameOver.
* The [[MetalSlime Mystery Metal Monkey]]. Defeating it gets you good experience. Literally.
-->'''Battle Memory entry:''' "It was a good experience!"
* In the [[{{ItMakesJustAsMuchSenseInContext}} flying limousine]] at the start of Chapter 8.
--> (''Upon examining row of liquor'') "Grownup drinks are lined up here. [[{{Anvilicious}} It's spicy, bitter, yucky poison, so kids can't drink it.]] Oh wait. Grownups can't drink it, either."
--> (''Upon examining tabletop game'') "A tabletop game. It looks like you can play it, but you can't.
--> (''Upon examining billiards table'') "A 9-foot billiard table. The pockets have been designed to be quite large. It looks like you can play it, but you can't."
--> (''Upon examining blackjack table'' "A blackjack table. It's not a playable blackjack table, though."
--> (''Upon examining tower of champagne glasses'') "This is one of those famous champagne towers. Actually, upon closer inspection, it's only a painting."
** You should see what happens when they're relaxing on the (maybe) vibrating sofas.
--> (''Cue LuminescentBlush from entire group'') "What is this feeling?!"
* In the arcade in Chapter 8.
--> (''Upon examining one of the machines'') " 'Dance Dance Business Kimono'. What kind of game IS this?!"
* Any time you use an oxygen machine when you're underwater. Just so you know, the "oxygen machines" look like mermen with huge feminine lips. And they give you oxygen by kissing you. The whole party blushes in an embarrassed way when you're done.
* Talking to Nana, the girl by the beach. Before talking to her, she warns Lucas that everyone hates her for talking too much, and when you ignore her warnings, she goes of on a long talk about music and destiny, after which it cuts to black and back to the screen, where Lucas and Boney are dizzy from listening to her.
* The Pigmask Guard asleep on duty at the start of Chapter 7.
* "Okay... one... two... THREE! ''(Everyone runs away)'' ...Is when we run, got it? ''(Looks behind her)'' Oh. Damn. They're fast." ''(Runs away.)''
* [[ContinuityNod The Mischievous Mole felt]] [[VideoGame/EarthBound homesick]]!
* ''The [[RunningGag Rope Snake]].'' When you give an insignificant item that you use three times in the game emotions, HilarityEnsues.
* Also, the scene in Chapter 4 where [[TeamPet Boney]] dresses up like a kid to get into the nightclub.
---> "Shake! ...Oh, sorry about that. I just get that instinct when I look at you..."
** Also great is when the bouncers reject Lucas and Boney, they walk away sad and dejected, only to immediately walk back with Boney in his PaperThinDisguise.
* A particularly amusing moment in the otherwise bleak endgame: [[spoiler:Dr. Andonuts rolling Porky around in the Absolutely Safe Capsule.]]
* Don't forget the [[RunningGag doorknob]]!
* The present boxes that don't offer anything of value, not even a ChestMonster, can be a treat.
--> "Lucas opened the present." ''(Music plays)'' "You heard a mambo/reggae/waltz rhythm. Ah." \\
"Lucas opened the present." ''(Fireworks go off)'' "There were fireworks inside. Ah." \\
"Lucas opened the present." ''(The present box [[ToiletHumour farts]])'' "An indescribable smell lingers in the air."
* Every single sign ever.
--> '''Preserve our beautiful scenery! [[HypocriticalHumor Please refrain from posting signs.]]
* "[[DiedStandingUp He's passed out.]]"
** [[FridgeHorror "Don't come back here. You'll kick up the mold spores."]]
* "No problem here... problem here."
* "Thank you for taking the time to read this sign. This sign loves you."
* When you find out the real difference between the green and regular trains: [[spoiler:The green one gives you the the joy of riding a green-colored train. The other doesn't.]]
* ''The Barrier Trio strikes one final Barrier Pose! --- It was [[CrowningMomentofAwesome spectacular]].''
* When the group leaves Saturn Valley via Rope Snake holding onto a bird cage. Boney has to hold onto Lucas' shorts, causing his bare butt to be on display.
* There's something hilarious about how Duster, who has a paralyzed leg, attacks by ''kicking.''
* If you go around and read the graves near the beginning of the game, there will be grave puns. Don't laugh too hard, however, because this takes place in a [[LamePun "grave"]] situation.
* After you defeat the Forlorn Junk Man, a Pigmask arrives and hurriedly tells you to get in his Pork Bean. Once everyone is inside, he says that if anyone needs to use the bathroom, they just have to hold it in for now, which makes [[ToiletHumor Boney whine in response.]]

[[AC:VideoGame/{{Mother 4}}]]
* There's a [[FreezeFrameBonus brief moment]] in [[ the official gameplay trailer]] when Travis comes across a dumpster while he's dragging a fallen ally behind him- and then glances at the load weighing him down as if contemplating the obvious.

* Every time an enemy does an odd action during battle, an example being the New Age Retro Hippie who uses a ruler and can now measure the lengths of things more easily!
** While many of said actions are useless, there are the occasional few that are really weird AND have an effect, like taking the time to brush your teeth in-battle, making them so bright that they paralyze the target. Yep.
* Anything with the [[RidiculouslyCuteCritter Mr. Saturns]], really. Zoom!
* In a masochistic CrossesTheLineTwice sort of way, getting killed by one of the [[WhenTreesAttack exploding tree]] enemies, particularly if you did [[DoubleKnockout wisely save one for last but didn't mash A fast enough to fast-forward the battle text]].