In the first episode, Zoe is dropped off at her apartment and her date tries to invite himself up. Her declination is priceless. "Aw, Brian. If I was going to fuck you, you'd know." It sounds so sympathetic and endearing that it's like she politely turned him down for coffee rather than sex.
At the end of the first episode, everyone is reacting to the news story with various expressions of Oh Crap. Then, it cuts to Zoe, who is...on the crapper.
The county executives in Underwood's district debating about which piece of the female anatomy the Peachoid looks like.
Frank's "IOU" gaffe. It's refreshing to see that even pure evil can eat it raw on cable news. It wasn't even so much the gaffe. It was the fact that it went viral on Youtube and was turned into a hilarious Stupid Statement Dance Mix.