* The entirety of ''Channel Chasers''.
-->'''Wanda''': (referring to the violence in the WesternAnimation/TomAndJerry parody) Wow, you don't see [[AmusingInjuries cartoon violence]] like ''that'' anymore.
-->(later)
-->'''Cosmo''': Heeeeey, that's violent, too. Didn't they have [[MoralGuardians censors]] back then?
** And made even funnier by the fact that, each time, Wanda or Cosmo's head [[SelfDemonstratingArticle was blocking the violent scene]]. So no, Wanda, we ''don't'' see violence like that on TV anymore.
* That part when they go into a parody of Anime/SpeedRacer. If you watched the anime, you'll laugh a lot once those over the top explosions and facial close-ups with OhCrap expressions kick-in.
* Deep Toot, who ''[[SuspiciouslySpecificDenial is not]] Vicky's sister... ''Hmmmmmmmmmmmm...''
** Vicky's reaction when she's exposed. '''''WHO ARE YOU, DEEP TOOT'''''?!
** Especially funny considering it's a play on the Richard Nixon whistleblower, [[GettingCrapPastTheRadar Deep Throat]].
*** Timmy's dad is clearly getting the joke.
* When the masked figure is flying through the TV universe, he is hit by a floating block, sending him to [[WesternAnimation/StrawberryShortcake Paula Poundcake]].
--->'''Donny Donut''': (in a deep voice) And I'm Donny Donut. And [[RealMenWearPink even though I'm a boy]], I still think this place is swell.
--->'''Everyone''': Our icing is nicing!
--->'''Future Timmy''': Get back, you frosted freaks, Back!
** Paula introduces her pet "Pup Tart" who's literally a sentient pop tart. Then she takes a bite out of him causing him to bark in panic.
* [[Franchise/ScoobyDoo "Like, what was all that about, Snoop?"]] [[Music/SnoopDogg "Yo, I don't got all the answers, man."]]
* "TAXES ARE TOO HIGH!"
** "EAT MY RIGHT WING, PUNK!"
* The Franchise/{{Batman}} Parody.
** '''CURSE YOU, QUIZZLER!!!!!'''
** Bonus Points for still being voiced by Creator/AdamWest, despite not being ''Catman''.
* Really? This far and nobody mentions how in the opening Chester still has his braces and they're a WEAPON?
-->'''Chester''': (After having the masked figure punch his teeth.) Now I know why I never had these things taken off.
* Future!Chester and Future!A.J. stopping to blow up the ruins of Dimmsdale Elementary and bask in the fact a place they hated is now wiped clean from the world.
* The Blue's Clues parody, Clint's Hints, a huge [[TakeThat take that]] to the show, especially the human character, named Jeff (parody to the host Steve, and his replacement Joe.)
-->'''Jeff''': (appears & does a cartwheel into the scene, & flips to the audience) Hi, kids! I'm Jeff! (gets up close to the camera) Ignore the shaving cut and the five o'clock shadow. I'm really a kid, just like you. Hey, let's go find some hints! (runs backwards away from the camera) Some Clint's Hints! (gasps & jumps) Come on!
* Future Timmy making the same mistake as his parents.
* Tootie's and Chester's reactions to the mass mind wipe:
-->'''Tootie:''' Was I doing something Timmy-related?
-->'''Chester:''' Were we doing something Timmy-related?