An encounter at the University can result in you giving a guest lecture about the Mythos... only for everyone to conclude you're off your rocker and ship you to Arkham.
One of Wendy Adams' abilities, Minor, prevents her from getting a bank loan. However, it does not stop her from becoming the Deputy of Arkham. What makes this even more hilarious is that "Skids" O'Toole has a similar ability, Criminal Record, that does stop him from getting a bank loan or becoming deputy. So we can conclude from this that a homeless little girl is more trustworthy than a former criminal.
His Personal Story involves finding "Pa" Samson, who vanished after he tried to complain about losing his luggage (e.g., the crated remains of the bird-monster Hank had shot). A success involves Hank finding "Pa" Bound and Gagged, and delivers this little line: