* Fascinating tidbit I learned while messing around on my second playthrough. For fun, I was trying to figure out where Trauma Team was located. The city "Portland" is referenced multiple times as being the location of the majority of the game. Makes sense that a simple name would be used, [[WhereTheHellIsSpringfield considering there are fourteen in the USA]]. That said, my interest was piqued when I learned there are bits in the Raging Bomber case that mention southern New Hampshire and Higgins Beach. The search could then be narrowed down. Searching and finding that Higgins Beach is an actual location in Maine, it's safe to assume that the game is set in Portland, Maine. This is backed up by there being an airport in the city. [[note]]the game calls it Portland Airport, but the actual name is Portland International Jetport. We can let that one slide.[[/note]]
** That's all well and good and preamble, but here's the [[FridgeBrilliance brilliance.]] I figured there was no way there could be a Resurgam First Care in Portland, ME, right? That'd be silly. Well, turns out there isn't, but here's the big one. "Resurgam" is a Latin phrase meaning "I shall rise again". Makes some nice referral to the idea of saving lives and all, but it's also ''the city motto of Portland, Maine.'' My jaw dropped.
** And having looked up on the [[WikiRule Caduceus Database]], it seems this legwork was done already before my epiphany, so I may as well also mention that there's further evidence for the location: CIFM (where Naomi works) is the Cumberland Institute for Forensic Medicine. Cumberland County is in Maine. Also, Naomi takes a trip up to Oxford, which is in the mountains, a place that exists in Maine.
** Only one problem with this theory: page five of the instruction book for the game explicitly states that Resurgam is located in Maryland. Also, there is a Cumberland, Maryland.
* Why is it that you get points bonuses if you complete additional parameters while operating in Trauma Team? Because not being thorough is an issue when performing routine procedures. You always hear of those medical horror stories of patients with medical equipment left behind, right?
* During the GUILT outbreak in Elysium, Emilio, a former Sinner and one of the infected, claims that his history of being a Sinner gave him antibodies that could at least help buy him some time. He succumbs to the disease anyway. Why? Dramatic reasons aside, antibodies are very specific - what works for one strain of a virus will not necessarily work on the other. Given that Emilio was a Sinner for Pempti (based on location of his PGS and process of elimination) his antibodies would not help against Kyriaki.
* In Trauma Center 2, [[spoiler: They say that the two Sinners and Adam's son react violently to the anti-GUILT serum because they have GUILT that hasn't been encountered before so the serum doesn't properly take that into account like the spore tumor one. However when you do surgery on them they have the 3 GUILT strands from the previous game and ones known to be cured by the serum.]]
* Instead of expecting the surgeon to constantly inject vital fluid during operations where their attention is needed practically everywhere at once, why don't they just hook up the patient to an IV filled with the stuff?
* In ''Under the Knife'' and ''Second Opinion'', Tyler Chase makes the decision to euthanize [[spoiler:Amy]] without even asking for her consent and doesn't seem to see anything wrong with that until she tells him to his face that she wants to live. Given that we know that he's been working as an euthanasist for quite some time before that, this kind of raises the question whether he has euthanized patients without their consent before - and regardless of one's stance on voluntary euthanasia, it's hard to call involuntary euthanasia anything other than straight-up murder.