Dr. Oliver Thredson getting various facial injuries (Getting a picture frame smashed onto his face, and later a fire extinguisher) signifies that he's starting to look more like his alter ego Bloody Face.
In "Murder House", Zachary Quinto's character attempts to please his boyfriend by buying and wearing a rubber bondage suit that later becomes the costume of the 'Rubber Man' murderer. Said boyfriend dismisses it, saying he prefers leather. In "Asylum", Quinto's character turns out to be the 'Bloody Face' murderer, whose mask is made from the leathery remains of women's skin.
Dr. Thredson is left alone with a demon-possessed boy early on in the series. The scene cuts away; when it returns, the boy is in convulsions, and the clinically-minded Doctor recommends sedating him. In a later episode it is revealed that the Demon possessing the boy was aware that Thredson is "Bloody Face". Therefore it is more-than-likely that Thredson panicked and killed the boy by lethal injection in order to protect his secret life.
Lana's alterations to her book make much more sense if she's still traumatized from other off-screen activities Thredson did to her, still coping with Wendy's death, and in a roundabout way, keeping her son from being sought out by people fascinated by Bloody Face. Even if she says her embellishments are largely because of ambition and societal norms at the time.
The song "Dominique" was composed and sung by Jeanine Deckers, a lesbian nun who killed herself. Rather fitting.
The opening credits commonly don't include an actor appearing on the show until the episode they're actually appearing in. It may seem pretty odd, then, that Zachary Quinto is in the credits of the first episode despite Thredson not appearing in that episode at all. However, Bloody Face makes an appearance in that first episode. So from the beginning, the credits hinted at who Bloody Face really was.
It's not like she was responsible for what the devil did.
Those creepy images you see in the opening theme of every episodes? The more violent ones are Thredson and Arden dissecting people.
So you think that Dominique song is annoying when listening to it on the show? Now imagine the inmates (who are not well) have to listen to it, All Day, EVERY day.
the season ends with the song playing to give the audience a feeling of going crazy (with everything horrible about to repeat all over again in an agitating loop).
In Madness Ends Lana's report shows that Briarcliff decayed after the nuns left. That's right, Briarcliff is worse off when managed by the State than when it was run by A Nazi war criminal, a serial killer and the Devil