Doki Doki Literature Club!: Sayori was this as her depression worsened even further due to Monika's meddling. Regardless if you friendzone or confess to her, she will kill herself because both decisions cause her nothing but immense pain.
Animula's backstory involves this in Little Apple Dolls. She was betrothed to a warlord prior to her birth by her father, in order to avoid losing his wife. On her seventh birthday the warlord comes for her. The little girl is made to live in a cage, however a fox comes along and helps her. She said the warlord was going to give her milk that would turn her into a demon. Animula is given eggs in order to protect her. It turns out the fox was really the warlords' jealous wife who was attempting to kill the girl herself. The little girl ends up drinking both the allegedly poisonous milk and eating the bad eggs, after she decides she can never escape.
In a story about a blind man (or in some versions a blind sailor) who eats seagull pie at a restaurant, he starts to notice the seagull meat tastes different to when he first ate it after he got stranded on a deserted island with his ship's Captain and lost his sight. Then the blind man realizes the Captain did not serve him seagull meat, but human meat from one of the dead crew members (in some versions of the story, it's the man's dead wife). The horrific truth that he ate human meat on the island causes the blind man to run out of the restaurant and kill himself by running into the path of an oncoming car.