* Sip every time:
** It's mentioned that John is missing.
** The apocalypse is mentioned.
** They get the monster wrong and have to do more research.
** You hear the line "saving people, hunting things, the family business" in the intro.
*** Take a shot if you hear a variation of this outside of the intro.
** Someone cuts their arm.
** The boys use a {{shoutout}} alias.
** Dean says "[[{{catchphrase}} Son of a bitch.]]"
** "Awesome" is used sarcastically.
** Dean says "Yahtzee".
*** Dean says "Ganked" or "Skeevy".
** Sam has a psychic vision (in seasons one and two).
** [[LeaningOnTheFourthWall The fourth wall is leaned upon.]]
** Castiel invades someone's personal space.
** Someone is bleeding from the mouth. [[note]] If you somehow haven't died of alcohol poisoning beforehand, the latter half of Season 8 ''will'' kill you in a matter of episodes.[[/note]]
** One of the main characters (Dean, Sam, Castiel, etc.) dies. [[note]]We advise you against watching [[GroundHogDayLoop Mystery Spot]] or Goodbye Stranger. Have an ambulance on alert if you choose to watch those.[[/note]]
*** Take two every time they come back.
** There is a scene in which Dean eats and Sam does not.
*** Finish your drink when Dean refuses food.
** Dean says "Chuckles," "Chucklehead," or any variant thereof.
*** Take three every time someone parodies this.
** Someone says 'get this.'
*** Take two if it's not Sam or Dean.
** If the intro has Dean saying "She's a demon, Sam!"
*** Take two if it's in reference to someone other than Ruby.
** When asked to justify an extremely dangerous, costly, painful, or downright irresponsible decision, the answer is, "Because you're my brother" (or some variant thereof).
** A random female character dies.
** A random male character dies.
** A ceiling fire occurs.
** You hear "Carry On My Wayward Son".
** Dean cries one single tear.
** Bobby says "balls" or "idjits". Finish your drink if the "idjits" comes from season 7's episode "Death's Door". Then cry.
** A dick joke is made. [[note]] If you're watching season 7, you should either be drinking water or ready for liver failure. [[/note]]
** Someone reminds Sam that the apocalypse is technically his fault
** Rock salt makes an appearance
** Dean or Sam wind up flat on their backs, being pummeled, with their weapon juuuuuust barely out of reach
** Dean calls his car 'Baby'/speaks to it like a lover
** An angel acts like a douche.

* Shot every time:
** Dean mentions pie
** Someone makes a deal with a crossroads demon.
** A character makes a [[BigEntrance big entrance]].
*** Finish your drink when it's Death. And then think about ordering pizza.
** Someone's impending destiny/doom is mentioned.
*** Take two if said character responds with "ScrewDestiny" or a variation thereof.
** Dean and Sam exchange their "jerk"/"bitch" insults.
** The brothers are mistaken for a gay couple.
** A ''named'' female character dies.
*** Two shots and a middle finger to the screen if she lasted more than one episode.
*** Do two if she died from [[DeathBySex Death By Sam]].
*** Finish your drink if she was an important character who never got into a sexual or romantic relationship with the boys. (i.e. their mom, Mama Tran, Ellen.)
** A named male character who isn't Sam, Dean or Castiel dies.
*** Take two shots if he comes back to life later.
*** Take three if he dies again.
** A hunter's funeral occurs.
** Sam or Dean keeps something important a secret from the other or does something dangerous or irresponsible behind their back.
*** Take two if this ends up getting someone else (or one of them) injured or killed.
** Take a shot every time the boys are hypocritical (i.e. blaming someone for doing something that they would do).
** Every time Dean drinks, drink. You'll wonder how he can even stand up.
** [[SchmuckBait Every time Dean and Castiel have a homoerotic moment together.]]
*** Take two shots if another character lampshades their relationship.
* [[TooDumbToLive Every time]] on Website/{{Tumblr}} when a user posts a ''Supernatural'' GIF in response to a completely unrelated post. Take another if someone [[LampshadeHanging lampshades]] it.


* Rules:
** Drink every time a character you love dies.
** Die of alcohol poisoning or sadness, whichever comes first. Make sure your close sibling or angel best friend are ready to resurrect you through whatever means possible.

As always, TV Tropes is not responsible for the state of your liver.