Take two shots if he breaks down right after doing something badass.
Take a shot every time the Dub goes overboard with the amount of cursing. Two shots if it ruins what was supposed to be a dramatic scene. Three shots if it actually makes you laugh.
Take a sip every time Shiro comes bursting out of some random location (pipes, the ceiling, ect).
Take a shot every time Yoh gets injured. Make sure to have 911 on speed dial.
Take two sips if someone gets hurt and it's not Yoh.
Take a drink every time Senji says "Dead center."
Take a shot every time Rokuro cracks his neck. Take another shot every time he mentions numbers or calculations. You'll be too wasted to move by the end of episode ten so make sure to have someone call 911.
Take a drink every time someone freaks out and it's actually pretty funny instead of disturbing.
Take a sip every time Ganta loses enough blood that it actually would've killed him in real life.
Take a drink every time Shiro eats some sweet. Again, make sure to have someone with you so they can call 911 because you'll need it within the first four episodes.
Take a drink every time something actually scares you or is disturbing.
Take a sip everytme Genkaku mentions something to do with music.