Played for Laughs in the RiffTrax of Twilight. Two girls are having a discussion in the high school's cafeteria, when one mentions, "We're talking Olympic sized." Mike Nelson is right on top of it, chiming in, "High school girls discussing wang sizes. We have officially hit rock bottom, gentlemen."
And in the 'Trax for The Star Wars Holiday Special, while watching Harvey Korman debase himself in a miserably unfunny sketch, Mike sighs and says, "Well, Nietzsche was right; dead as a doornail."
Austin Aries and Jimmy Jacobs took each other down all because of Lacey. Aries persuaded Lacey to leave her boyfriend and the Age of the Fall, only to have Jacobs lose even more of his mind and take Lacey out of ROH for good. The real damage to Aries was done after he won the feud with Jimmy Jacobs and moved on to Age of the Fall Lieutenant Tyler Black. The fans began to get behind Black after a series of matches against Nigel McGuinness and Bryan Danielson to the point where some of them began to boo A-Double.
In Christianity, Despair is one of the original Seven Deadly Sins, being later replaced by the sin of Sloth. In Eastern Orthodox denominations, it is counted as the 8th Deadly Sin, but it is still present in Roman Catholic theology and others, simply considered to fall under the category of Sloth (or simply as a lesser sin). Despair is defined as the loss of faith or hope (ie. in goodness, in God etc.), and thus is more about giving into nihilism or cynicism (esp. as an excuse to stop being good or to ignore evil) rather than simply feeling sad or depressed about anything in particular; it is counted as Sloth because it is considered to be the sin of "giving up", and its corresponding virtue is (respectively) Hope or Diligence.
From Der Glockner Von Notre Dame the German Darker and Edgier Musical Adaption of Disney's The Hunchback of Notre Dame Quasimodo shut's down and cuts ties with all of his perceived hopes of the world Out There and the rest of humanity after being tricked by Frolko into revealing the location of the court of Miracles, leading to the Capture of his only true friend Esmeralda and Phoebus, in the song Made of Stone.
Quasimodo: "And now I'm on my own Never Again to Wonder what's out there Let it remain unknown And my one human eye Will evermore be dry Until the day I die As if I Were made of Stone"