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Characters from Trauma Center: Under the Knife and Trauma Center: Second Opinion
Derek Stiles (Kousuke Tsukimori)
Voiced by: Takayuki Kondo (JP), Yuri Lowenthal (EN)
The main character of Under the Knife and Under the Knife 2. Decided to become a surgeon after his father died of an illness. Gifted with the Healing Touch, he was recruited by Caduceus after successfully operating on a patient with GUILT.
- Ass Kicking Pose: It seems to be part of routine before starting an operation.
- Book Dumb: Derek is really only kept around Caduceus because he's a genius surgeon, and definitely not for his skills as a doctor. Dr. Kasal even sends Angie along with him because he doesn't trust Derek in that regard (though it's rather pathetic that his nurse is a far better doctor than he is). Still, he gets better by Under the Knife 2, and is shown to be impressively competent by New Blood and Trauma Team (if only because you're not playing as him anymore). The first game does extensively examine this, at least. Derek's so-so bedside manner and mediocre diagnostics skills are acknowledged by other characters (he was never top of the class in med school and borrowed assignment answers) and nearly get him in very serious trouble while he's in general practice. Part of the reason he chooses to join Caduceus is because by that point he's aware his incredible surgical skills are far and away his best asset and an environment that focuses him on that exclusively will allow him to do the most good.
- Catchphrase: Let's begin the operation!
- Healing Hands: The Healing Touch counts as this.
- Heroic B.S.O.D.: After failing to save Emilio's life. It's so bad that he actually loses the use of his Healing Touch for a while.
- The Intern: Averted, the games start with him having just finished his residency.
- Last Minute Hookup: With Angie, in the second game.
- And even then you need to really, really squint. Fanbase opinion varies. Widely.
- Legendary in the Sequel: Maybe not legendary, but still, his actions in treating GUILT and PGS have made him known as a master surgeon in New Blood.
- My Greatest Failure: Just when he's operated on several patients and is ready to save him, Emilio's antibodies aren't enough, and dies. Derek doesn't take it very well.
- The Medic: His job.
- Older and Wiser: In New Blood.
- One of Our Own: He gets infected with GUILT in Second Opinion and has to be operated on by Dr. Kimishima.
- Previous Player-Character Cameo: Appears in an episode of New Blood and a postgame challenge, and can be heard in some of Naomi's flashbacks in Trauma Team and he and CR-S01 discuss Rosalia taking on the disease she had.
- Shut Up, Hannibal!: Every X-Mission starts with Derek openly rejecting Adam's statements.
- Super Title 64 Advance: In the English-language versions — Derek Stiles. Nintendo DS.
- Time Stands Still: He manages to do this with his Healing Touch during the Savato operations. Definitely a Moment of Awesome.
- Unwitting Pawn: In Trauma Center: Under the Knife 2, he becomes this for both Mercer and Reina.
Angela "Angie" Thompson Blackwell (Ange Tonegawa Amou)
Voiced by: Sachiko Nakamura (Under the Knife) and Ayako Kawasumi (Second Opinion onwards) (JP), Wendee Lee (EN)
An elite nurse with an International Nursing License who transferred to Hope Hospital and became Derek's assistant.
- Art Evolution: In the original Under the Knife, she looked a lot like a teenager despite being 21. Starting from the remake Second Opinion, she looks closer to her actual age.
- But Not Too Foreign: She is part-German.
- Establishing Character Moment: When Angie first appears, she arrives slightly late—because she either witnessed a man on a bus having a heart attack (Under the Knife) or witnessed a man getting hit by a car (Second Opinion), and in either case, she personally helped the man to the hospital and thus was responsible for the man receiving quick treatment. This establishes how hard a worker Angie is and how seriously she takes her job, in contrast to Derek's (initial) laziness.
- Foil: To Elena. While Angie is bolder and more skilled, she's rather emotionally immature and quick to anger, tears, and belittlement of others. Elena, on the flipside, is more composed, cheerier, and prefers to give the doctors positive encouragement instead.
- Hypocrite: Early on in Under The Knife / Second Opinion, Angie criticizes Derek for "not showing proper bedside manner" to a patient (even though all he did was tell him "we'll do the best we can"). A few chapters later, she and Derek save the life of a teenage, suicidal GUILT patient named Linda Reid. After Linda snaps at the two hospital workers for saving her, Angie responds by angrily telling her that saving her was a mistake and that she should just die. Way to follow your own advice, Ang.
- I Know Karate: "I have studied Aikido."
- Jerk with a Heart of Gold: She's The Lancer, but good God, she is such a bitch most of the time. She berates and blames Derek for Emilio's death when in reality he was forced to make a very difficult call as a doctor during a terrorist attack-level emergency that mirrors a sadly common situation doctors go through on a near-daily basis.
- Last Minute Hookup: With Derek, in the second game.
- Proper Tights with a Skirt: Frequently.
- Shipper on Deck: A very subtle example, but after Derek cures Dr. Greg Kasal of the Tetarti strain of GUILT, Cybil says that Dr. Kasal needs time to recover, even though he'll probably try to return to work right away. So Angie suggests that it looks like they're understaffed, so perhaps Cybil could assist Dr. Kasal?
- To Be a Master: When Derek finally decides to transfer from Hope Hospital to Caduceus, Angie goes with him, both because the hospital thought Derek needed someone he was familiar with to help him, and, as Angie explains, because Angie wants to be a "master assistant" just as Derek wants to be a master surgeon.
- Tsundere: Starts out as a Type A towards Derek, but gradually warms up to him. She still shifts back every so often, though.
- What the Hell, Hero?: Delivers two of these in the first Trauma Center: Under the Knife (and its remake, Second Opinion). The first one to Derek, when Derek's carelessness in refusing to analyze a patient in detail (so that Derek could attend a symposium) caused complications later on, and the second one to Linda Reid, because Angie believes that with so many people in the hospital struggling to live, if Linda wants to die then she should die, and make room for the others.
Nozomi Weaver / Naomi Kimishima (Mira/Mila Kimishima)
Voiced by: Akeno Watanabe (JP), Kirsten Potter (EN)
A foreign doctor working at St. Francis Hospital. Appears as a new main character in the Z chapter and Chapter 6 of Trauma Center: Second Opinion. Her Healing Touch manipulates the patient's energies and raises vitals when performing actions.She also appears in Trauma Team, as the protagonist of the Forensics mode. Now infected with an incurable disease, she works at the Cumberland Institute of Forensic Medicine to solve crimes.
- All of the Other Reindeer: In a way - Nozomi was disbarred as an official surgeon for "having magical powers", which led to her jumping ship to Delphi.
- Anime Hair: It is confusing as to how her Second Opinion hairstyle is physically possible.
- Ass Kicking Pose: In Second Opinion.
- Bad Ass Long Coat: In Second Opinion.
- Broken Bird: Her work with Delphi combined with finding out about her terminal illness makes her become this in Trauma Team.
- But Not Too Foreign: In the Japanese version, at least. She's a Japanese-American.
- She tends to begin The Summation by stating, "The dead shall speak. Let's put together the truth of what happened here." note
- In Second Opinion, she tends to say "Here Goes" before starting an operation.
- Earn Your Happy Ending: After everything she gets put through, Naomi deserved getting a clean bill of health and the chance to get to take care of her adopted daughter.
- Gratuitous English: In the Japanese version. The names of her operations are in English, even.
- Healing Hands: She has the Healing Touch as well, though hers works differently from Derek's.
- Heroic B.S.O.D.: Naomi has one in Trauma Team when Alyssa gets blown up.
- One of Our Own: She is the patient for the final operation in Trauma Team.
- Mistress and Servant Boy: Her and Little Guy's relation ship in Trauma Team has shades of this.
- Ms. Fanservice: In Second Opinion. Downplayed in Trauma Team for the most part, but a lot of her cutscenes intentionally give the viewer an eyeful of boob.
- Older and Wiser: In Trauma Team.
- One-Note Cook: The only dish she can cook well is curry, which she learned during her time in India.
- Parental Substitute: Naomi feels obligated to raise Morality Pet Alyssa after she gets nearly killed in a bomb meant for her
- Phone Call from the Dead: Has the ability to receive the final words of the deceased through her phone in Trauma Team, by making contact with the corpse (or its remains).
- Pop Quiz: All over the place in her portions of Trauma Team.
- Super Title 64 Advance: Her Second Opinion alias, Nozomi Weaver.
- Your Days Are Numbered / Soap Opera Disease: After Second Opinion, she's diagnosed with an incurable disease that leaves her with only about a year of life left, only for it to later combine with the Rosalia Virus. When she's cured of the mutated (aka "Twisted") Rosalia in the last operation, the disease dies along with it, leaving her to take care of her new adopted daughter, Alyssa.
Mary Fulton (Momoe Furumura)
Voiced by: Chisato Sugawara (Under the Knife) and Mai (Second Opinion onwards) (JP), Wendee Lee (EN)
A veteran nurse at Hope Hospital. She serves as Dr. Stiles's assistant in the first few episodes of Under the Knife. Because her husband was relocated to a different office, she had to leave to work at a different hospital. She is replaced by Angie Thompson. She later makes a surprise appearance in Under the Knife 2 to aid Derek recover from his depression.
- Catchphrase: She doesn't really have one, but fans have noted how often she berates Derek with the "You're such a handful!" line in Under the Knife 2, even if the in-game text says otherwise.
- Memetic Mutation: When her spoken line reaches unbelievable levels. "YER SOSCH EH HENDFOOL!"
- Shipper on Deck: To Derek x Angie, in Under the Knife 2.
Tyler Chase (Tougo Sakura)
A surgeon at Caduceus. A friend of Derek's from medical school.
- Big Brother Instinct: Well, can you really blame him?
- Big Brother Mentor: When we're first introduced to Tyler's sister Amy, Amy hasn't done her homework because she thinks it's "boring", but Tyler explains (with a bit of self-deprecation) that if she doesn't do it, she'll turn out dumb like her big brother, and she wants everyone to know how smart she is, doesn't she?
- Brilliant, but Lazy: He's a good doctor, but he doesn't like to work very much.
- Drill Sergeant Nasty: In the sequel, he's known to be very strict with his interns, who nicknamed him "The Demon".
- Genius Ditz: Despite not liking to work very much, as noted under Brilliant, but Lazy above, Tyler is very good at writing detailed theses. Which is why Derek doesn't turn Tyler in for euthanasia after Amy is cured, as Tyler's skills can still be used to help save lives instead of ending them.
- Shipper on Deck: To Derek x Angie.
- Shoot the Dog: He was an euthanasist before Derek changed his mind by saving his little sister's life. While slightly ambiguous, it's implied that he was doing this in an unofficial (and illegal) capacity.
Victor Niguel (Shuuya Aragaki)
Voiced by: Kazuya Niinou note (Under the Knife) / Masaaki Kouda (Second Opinion onwards) (JP), Spike Spencer (EN)
Head of Caduceus's research division. Known as "the brain of Caduceus". Considers diseases as enemies on a personal level.
- Cluster F-Bomb: The guy provides the greatest source for swear words in the game.
- Grumpy Bear: Stands out as a cynic in a mostly idealistic series.
- Heroic B.S.O.D.: Has a minor one after Anderson's death.
- Insufferable Genius: Though the "insufferable" part isn't played up all too much.
Stephen Clarks (Takuji Houshou)
Caduceus's veteran surgeon.
- Depending on the Artist: In the stylized Under The Knife artwork, he looked severe and serious. The updated artwork shown here makes him... rather goofy.
- Game-Over Man: His main role is jumping in to take over if you fail an operation.
Leslie Sears (Yuno Itou)
A nurse at Caduceus.
- Depending on the Artist: Originally, she looked young but matronly. The updated artwork plays up her youth.
- You Gotta Have Blue Hair: Her green hair sticks out in a cast with mostly normal hair colors.
Sidney Kasal (Souji Kutsukake)
Chief Director of Caduceus. Dedicated his life to medicine after his wife died of illness. Younger twin brother of Greg Kasal.
- Scary Shiny Glasses: More to show that he's tense than to be threatening, though.
Greg Kasal (Shin'ichi Kutsukake)
Chief surgeon at Hope Hospital. Later becomes the director after Robert Hoffman leaves for Caduceus. Older twin brother of Sidney Kasal.
- Big Brother Mentor
- Game-Over Man: In the early operations of Under the Knife and Second Opinion, he takes over if Derek allows the patient's vitals to empty out.
- One of Our Own: He gets infected with Tetarti in the first game. He requests that Dr. Stiles perform the operation instead of Dr. Clarks, as the final test as his mentor.
Cybil Myers (Sayaka Myoujin)
Voiced by: Mizuho Adachi (Under the Knife) / Fuyuka Ooura (Second Opinion onwards) (JP), Wendee Lee (EN)
Anesthesiologist at Caduceus and a former police officer, nicknamed the "Iron Vixen". In Under the Knife 2, she has married Greg Kasal and works with him at Hope Hospital.
- Chekhov's Skill: Her police officer training, as she dated a guy on the bomb squad and thus, in the present day, can advise Derek on how to dismantle a bomb.
- Drill Sergeant Nasty: When Derek first meets Cybil, Tyler jokes that Cybil is this, and that she'll never work with Derek again if he screws up. This is a joke on Tyler's part, and Cybil isn't really any stricter to Derek than the rest of the cast, except when she scolds him for panicking over the bomb, but that was just to shock Derek into attempting to solve the problem.
- Nerves of Steel: Cybil got the nickname "Iron Vixen" due to her ability to remain cool under pressure.
- One of Our Own: She is infected with Paraskevi in the first game.
- Shipper on Deck: To Derek x Angie, in Under the Knife 2.
Robert Hoffman (Iichirou Kitazaki)
Director at Hope Hospital. Is gifted with the Healing Touch, but has retired from surgery. Later becomes Executive Director of Caduceus.
- Badass Beard: It becomes very spiky in his Second Opinion re-design.
- The Comically Serious: When Cybil and Greg Kasal take off to handle the incoming patients (all being sent to Caduceus) due to a big accident on the freeway in Under The Knife 2's 3-5, they leave him to take care of their baby in the meantime. Hilarity Ensues.
- Let's Get Dangerous!: In Under the Knife, he wears a somewhat vacant expression on his face until this moment, when he becomes much more serious-looking. This effect is also present in Second Opinion, but it is much more subtle.
- One of Our Own: He is the patient in the final operation of Second Opinion.
- My Greatest Failure: After losing a patient in quite a messy way, he never used his Healing Touch again.
- Retired Badass: He had a Healing Touch just like Derek before... well... crap hit the fan.
Langston Miller (Lewis Willer)
The Chief Director of Caduceus Europe. He oversees the military operations in Africa and at Delphi's base.
OwenThe Chief Researcher at Caduceus Europe. He was in charge of a project to use "Z-Cells" from Adam's body as a regenerative treatment for patients.
Adam / Erick Von Raitenau (President)
Delphi's President, and a very bad guy. Put into suspended animation by GUILT.
- Big Bad: In the first game, his influence is felt in Trauma Center 2 as well, and though he has no direct hand in the events of Trauma Team the final boss is the result of Rosalia mutating due to Naomi's GUILT-born genetic disorder.
- Body Horror: Just... look at him!
- Evil Gloating: "No matter how hard you try, you cannot overcome the power of Death!"
- Evil Is Not a Toy: The sixth chapter of Second Opinion reveals that his body is preserved and is being used to create Z-cells that vastly improve patient recovery, even though this is essentially using Adam's unique GUILT strain for this purpose. Nozomi lampshades this trope, saying that it's bound to backfire. True enough, this ends in a GUILT outbreak at the conference, and the reveal that the scientist leading development for Z-cells is a Delphi remnant.
- Game-Over Man: If you fail one of the X operations."Mankind strives toward death...only a fool would deny that."
- A God Am I: "I, who have become the Great Destroyer Apollyon!"
- Hypocrite: Sure, Adam, it is wrong for doctors to allow people to live longer, but when YOU make yourself immortal, it's alright... Like every good hypocrite, Adam even has a rationalization ready - he claims that, in his "undead" state, he has placed himself outside the cycle of nature, so even if he doesn't actively better the world, he doesn't take anything from it either.
- Late-Arrival Spoiler: Second Opinion's box art displays him rather prominently on the front.
- Nietzsche Wannabe: Yet he also thinks that he's serving God- he even goes so far as to identify GUILT with the Seven Plagues of Revelation and proclaims he will smile as Derek and friends burn in Hell for opposing the Divine Plan.
Kenneth Blackwell (Kyouji Amou)
Voiced by: Joji Nakata (JP)
A scientist forced to work with Delphi to create GUILT.
- Anti-Villain: Sure, he may work for Adam, but he's so horribly ashamed about it that one can't help but feel sorry for him. Not to mention, the only reason he accepted to join Delphi in the first place was to protect his daughter Angie...
- The Atoner: After Derek saves his life.
- Catchphrase: "Indeed..."
- Death Seeker: Before the operation that saved his life, Blackwell believed that getting infected with Savato and dying from it was his just desserts for his crimes.
- Reverse Mole: He joins the Hands of Asclepius in Under the Knife 2 in order to investigate their activities and uncover the origin of Neo-GUILT.
Delphi Assistant/"Little Guy"/FBI Agent/Navel ("Little Boy")
Voiced by: Hiroki Tochi (JP), Yuri Lowenthal (EN)
A, uh, Delphi assistant in Trauma Center: Second Opinion. He acts as Dr. Kimishima's assistant in the Z chapter. By the time of Trauma Team, he's taken on a job at the FBI under an assumed name; when Naomi gets partnered with him once again, she quickly gives him the nickname "Little Guy".
- Ascended Extra: In Trauma Team.
- Berserk Button: He's a music lover, so he (to Naomi's confusion) gets a little pissed when a valuable guitar gets damaged in a bombing.
- Bishōnen: Particularly in Trauma Team where his hair is styled to make him look younger.
- Dogged (Semi)Nice Guy: He has a plain crush on Dr. Kimishima, who usually either shoots him down or mocks him. However, as the player progresses through Forensics, Naomi will begin to flirt back every now and again.
- Drives Like Crazy: Averted, when speeding along a mountain road in Second Opinion, he explicitly mentions he's had training in aggressive driving. The journalist he's trying to ditch hasn't, though, and suffers the consequences.
- Mistress and Servant Boy: His and Naomi's relationship in Trauma Team has shades of this.
- Refuge in Audacity: A terrorist who goes into hiding by... joining the FBI.
Linda Reid (Sayoko Ooga)
A teenage girl who wishes to die. Suffering from the GUILT Kyriaki, and later post-Kyriaki.
- Driven to Suicide: Not that she actually did anything about it. GUILT would have done it for her.
- Dub-Induced Plot Hole: A minor example, but her age in Under the Knife 2 is listed as 17, the same as in the previous game, despite the three-year Time Skip. This is because in the first game's Japanese version, she was only 14 years old. The translation upped her age to 17, but that wasn't taken into account by the second game's translation.
- Emo Teen: In her defense, depression is a symptom of GUILT infection.
Amy Chase (Rin Sakura)
Tyler Chase's younger sister. Was suffering from the Deftera strain of GUILT.
- Cheerful Child: She's usually drawn smiling, and she's pleasant and friendly to talk to. Her being a cheerful child actually becomes a plot point, as she decides to undergo a risky surgery she knows has a low chance of succeeding because she wants to live and work hard like her big brother.
- Girlish Pigtails
- Heartwarming Orphan: Her purpose in the story is to drive home to the player how arbitrary GUILT is and how much it makes innocent people, such as sweet little girls like Amy, suffer. So the player will be more motivated to take down Adam, the guy who created the disease, rather than get emotionally invested in destroying something that essentially has no ill motives.
- Hidden Depths: She's the one who snaps her big brother out of his "death is better" mindset. How? By consenting to a difficult operation performed by Derek which doesn't have great odds of succeeding, just because she wants to live and work hard together with her big brother.
- Ill Girl: But Derek does manage to cure her eventually.
Richard Anderson (Katsuhisa Hibiya)
The Secretary of Health and Human Services and the Executive Director of Caduceus.
- Hope Spot: Despite all of Caduceus' - and the player's - efforts, Anderson's body gives out shortly after he is freed of Pempti. However, Anderson anticipated this might happen and donated, in advance, all the results of the treatment on his body to help fight GUILT in the future.
Seven children from around the world that were kidnapped by Delphi and used as living incubators of the GUILT strains that Derek has been treating. In the original Trauma Center 1, they are operated on one at a time and then taken into protective custody, but in Second Opinion, this doesn't happen due to the events taking place in one expositionary cutscene.
Characters from Trauma Center: Under the Knife 2
Voiced by: Shintaro Asanuma (JP)
A young doctor from the African Republic of Costigar. He's recommended to Caduceus by Derek Stiles, but leaves to join the HOA.
- Ax-Crazy: Under the influence of the Neo-GUILT Sige, he comes close to using the Healing Touch to shank Derek with a scalpel.
- Bishōnen: His light build, full lips, large eyes and long hair make him easy to mistake for a woman.
- Broken Pedestal: Finding out that Dr. Stiles, his mentor, couldn't (or from Adel's perspective wouldn't) operate on him shatters their friendship.
- Decoy Protagonist: The beginning of the story is told more from his perspective than Derek's, for the benefit of new players who aren't already familiar with the setting. When they have a falling out, the perspective stays with Stiles while Adel goes his own way.
- Dude Looks Like a Lady
- Face–Heel Turn: Because of brainwashing, but he himself admits later that it would not have worked if it hadn't exploited dark feelings he already had.
- Freudian Excuse: For his above Face–Heel Turn. It turns out he always felt it unfair that he was unable to completely help his people, while Derek and others were so successful because of access to such good resources and tools. That's why he took a fake Healing Touch and joined the dark side, so to speak, to improve his own skills.
- Good Powers, Bad People: Dr. Stiiiiles... Do you know what else the "Healing" Touch is good for...? It's also good for... KILLING!
- Green-Eyed Monster: His envy of Derek's Healing Touch and the feeling that he Can't Catch Up to such natural talent drives his actions for a good portion of the game.
- One of Our Own: He has to be operated on twice. The first time, Dr. Stiles is in the middle of a BSOD and can't handle it.
- Red Eyes, Take Warning: After joining the Hands of Asclepius. Since they were already brown, it can be hard to figure out why he's suddenly falling into the Uncanny Valley.
- Slasher Smile: He shows a terrifyingly twisted grin when he goes crazy.
- With Great Power Comes Great Insanity: Sige gives him the power to use the Healing Touch. It also drives him stark raving mad.
Heather Ross (Ayaka Isshiki)
Voiced by: Mamiko Noto (JP)
A nurse at Elysium, a facility created to look after GUILT patients. She has the same International Nursing License as Angie.
Reina Mayuzumi (Rena Mayuzumi)
Voiced by: Yuko Kaida (JP)
President of Acropolis Pharmaceutical.
- Older Than They Look: She's 35, but looks like a young woman. This is a side-effect of being infected by a dormant Aletheia. When Aletheia activates, her old appearance comes back with a vengeance, making her look far older than she is.
- Rapid Aging: When the dormant Aletheia in her body is awakened, she suddenly shrivels into an old woman. After she is operated on, she returns to her youthful appearance
Patrick Mercer (Akihiro Nagasawa)
Voiced by: Masaaki Kousa (JP)
CEO of the Hands of Asclepius. A bureaucrat with an ambition to reform the medical system.
- Badass Boast: "Witness the power... of GUILT!" So badass it gets its own sound clip.
- Cool Old Guy: Or maybe not...
Tracy Mercer (Hiromi Nagasawa)Patrick Mercer's wife. In a coma from an accident.
Heinrich von Raitenau
Voiced by: Atsushi Ono (JP)
Grandson of Adam. Continues his work along with remaining Delphi members.
Characters from Trauma Center: New Blood
Voiced by: Rikiya Koyama (JP), Troy Baker (EN)
One of Trauma Center: New Blood's two protagonists. Capable of using the Healing Touch. His Healing Touch is the same as Derek's.
- The Atoner: Not for an intentional misdeed, but his research was misused to create Stigma, so he is partially responsible for Stigma's existence.
- Deadpan Snarker
- Kick the Son of a Bitch: He refuses to let Vahkushti blame his actions on anything but himself and pretty much tells them to just shut up and die already.
- The Knights Who Say "Squee!": A mild example as he's too serious to squee, but he does have high respect for Derek, and mentions there's a lot of things he'd like to ask a master surgeon like him.
- No Sense of Direction: Not as bad as some comical cases, but Valerie points out he has all the cardiac blood vessels memorized, but can't follow street directions.
- Red Oni, Blue Oni: The blue one.
Voiced by: Yumi Touma (JP), Kimberly Brooks (EN)
One of Trauma Center: New Blood's two protagonists. Followed Markus Vaughn to Alaska to learn the Healing Touch. She eventually masters a Healing Touch that prevents the patient's vitals from changing for a period of time.
- Red Oni, Blue Oni: The red one.
Voiced by: Ryoka Yuzuki (JP), Karen Strassman (EN)
A nurse who was a patient of Markus Vaughn as a child. She followed him to Alaska for a follow-up operation, then became his assistant.
- Ascended Fangirl: In-universe. She went into medicine after being inspired by Markus performing surgery on her as a child, and is utterly delighted when she ends up as her hero's assistant.
- Foil: To Angie. While Angie is bolder and more skilled, she's rather emotionally immature and quick to anger, tears, and belittlement of others. Elena, on the flipside, is more composed, cheerier, and prefers to give the doctors positive encouragement instead.
- Unfortunate Names: "Salazar" is not only the given name of a fictional villain (Salazar Slytherin in the Harry Potter books), but also the surname of a real-life dictatorial head-of-state (António de Oliveira Salazar, prime minister of Portugal from 1932 to 1968 and founder of the authoritarian Estado Novo regime). Not exactly the most pleasant namesakes a person can have.
- Wise Beyond Her Years: She may only be 20, but she's very wise and strong-willed for her age due to her illness, something Valerie notes.
Voiced by: Ikuya Sawaki (JP), Dan Woren (EN)
The Director of Montgomery Memorial Hospital.
- One of Our Own: He has to have tumors extracted from his small intestine. He retires soon afterwards (He had planned on doing this anyway, but his surgery sped up his decision).
Voiced by: Shinobu Sato (JP), Mona Marshall (EN)
A nurse at Montgomery Memorial Hospital.
Voiced by: Yuri Lowenthal (EN)A helicopter pilot who transfers patients for Montgomery Memorial Hospital.
Voiced by: Hochu Otsuka (JP), Doug Erholtz (EN)
Chief surgeon at Concordia Medical Institute.
- One of Our Own: He suffers from burns and has to get a skin graft.
- Red Herring: He acts like such a jerk the player will probably assume he's up to no good and is going to screw someone over. Then it turns out later on that he's the one who gets victimized, and he has to be treated for skin burns after being attacked.
Voiced by: Matsuri Kawatoko (JP)A doctor at Concordia Medical Institute.
Voiced by: Shozo Iizuka (JP), Michael McConnohie (EN)
A professor at Concordia Medical Institute who conducted research with Markus Vaughn. He becomes infected with Stigma and urges Markus to come back from Alaska.
- High-Class Glass
- Laser-Guided Amnesia: His memory regresses significantly after his mind-control device is disabled.
- One of Our Own: He's the patient of the first Stigma operation, with Cheir on his heart. Later, you have to deactivate a mind-control device implanted in his brain.
Voiced by: Gara Takashima (JP), Mary Elizabeth McGlynn (EN)
The director of Caduceus USA.
- Awesomeness by Analysis: Is the first character to notice Markus is hiding something, possibly about Stigma. Irene notices by looking closely at Markus's body language. She gently but firmly tells him to be more honest and trusting with the team.
- Big Good: Since the first moment she's onscreen, she's shown to be a virtuous, if not shrewd (invokes Federal government authority to get them to join Caduceus, as a form of conscription) surgeon: she always regrets putting Markus and Valerie in the middle of danger and is usually sympathetic and supporting to them. That degree in Psychology helps.
- Cutting the Knot: In light of the new threat of Stigma, Irene pulls rank to recruit Dr.Vaughn and Dr.Blaylock immediately.
- Expy: Of Sidney, with the only difference being that Irene is far more open and talkative than he is.
Voiced by: Kaori Akashi (JP), Karen Strassman (EN)
A surgeon at Caduceus USA.
- Jerk with a Heart of Gold: Starts out with polite respect for the heroes, but is otherwise being very distant and cold. She grows out of it quickly after they save her cousin from a car accident and they escape from their captors. During both of these events,  she harbors intense guilt: for yelling at her cousin Koshiro so harshly and for being unable to help Markus and company when they are kidnapped.
- Scary Shiny Glasses: When she gets mad or serious.
Voiced by: Sanae Kobayashi (JP)A nurse at Caduceus USA.
Voiced by: Masuo Amada (JP), Greg Eagles (EN)Caduceus USA's chief surgeon.
- Game-Over Man: Usually the person who takes over if you screw up.
- One of Our Own: The very first thing you do upon meeting him is perform an emergency surgery on his cholelithiasis.
- Too Dumb to Live: Not exactly this trope, but Irene Quatro mentions he has been in pain from his gallstones for three years.
Voiced by: Tomohisa Aso (JP), Kirk Thornton (EN)Head of research at Caduceus USA. Talks in a very long-winded manner with lots of scientific-sounding words.
Voiced by: Derek Stephen Prince (EN)The president of Humani, a medical corporation that's partnered with Caduceus.
Voiced by: Karen Strassman (EN)A representative of Humani.
Voiced by: Mamiko Noto (JP), Wendee Lee (EN)
A research specialist from Humani who cooperates with Caduceus. A friend of Valerie Blaylock from medical school.
- Rule of Symbolism: When Valerie and Markus find her trapped in her religious fanatic boyfriend's castle, she isn't wearing the ornamental cross she had been wearing for the greater part of the story.
Gloria MendesThe Secretary of Homeland Security.
George MarshallThe Deputy Secretary of Homeland Security.
Voiced by: Kenji Hamada (JP), Derek Stephen Prince (EN)A skilled surgeon who knows the Healing Touch and performs operations live for the TV show "Miracle Surgery". Highly critical of Caduceus.
- Cooking Duel: Bizarrely, a surgery duel.
- Fake Ultimate Hero: He unveils his Healing Touch (slow-time flavor) to much fanfare, but it appears to be rather weak - he can't sustain it for long, he passes out foaming if he does use it for too long, and it's implied Markus's is much more effective.
- Insufferable Genius: A deliberate example; he's convinced himself that if his criticism forces Valerie and Markus to improve, then it will have served its purpose. Since his criticism is completely off-base, however, this is delusional on his part.
- Smug Snake: He makes no attempts to hide the fact that he doesn't think much of Caduceus, and thinks of himself as the greatest surgeon in the country.
- Wearing a Flag on Your Head: Not in the actual game, but in his profile picture on the official site, his tie has an American flag pattern.
- Combat Commentator: Or rather, "surgery" commentator, but fits nonetheless, especially given how intense surgeries can get.
- Most Annoying Sound: In-Universe, his loud comments about the on-going surgeries piss Markus and Valerie off.
Zachariah "The Kid" Kidman
Voiced by: Wotoya Kawano (JP), Doug Erholtz (EN)A mysterious criminal who wants to profit from Stigma by selling it as a biological weapon.
- All There in the Script: His first name is never actually spoken in the game.
- Karmic Death: He wanted to make money out of Stigma by selling it as a weapon, but as a result, he got caught up in the conflict that was rising in Culuruma, and died in one of the battles. For extra irony, he also got infected with two strains of Stigma prior to his death.
- Psychopathic Manchild: He attempts to drown the heroes to death by sealing them in a contraption based off a kid's toy!
Voiced by: Yuri Lowenthal (EN)An intimidating man working for Kidman. He oversees Markus and Valerie's operations and gives them the serum to treat Onyx.
Voiced by: Daisuke Kirii (JP)A shady man who snuck into Concordia Medical Institute. He was later hired to kidnap Markus, Valerie, and Elena for Kidman. He tried to run away afterwards, but was shot down and had to be operated on.
- Chekhov's Gunman: First seen trying to get drugs off Concordia, only to get turned away. He reappears as one of Kidman's minions.
Voiced by: Karen Strassman (EN)A young doctor in training from Culuruma.
- What an Idiot: In-universe. Markus and Valerie call her out on skipping her Vaimahse Fever immunizations for very flimsy reasons (she believed she was already immune to the disease as she was born and raised in Culuruma) when she really should have known better.
President Moreno (Javier Chaves)President of the South American country of Culuruma.
- Does This Remind You of Anything?: In the Japanese version, this controversial South American president is named Javier Chaves. He's the only character from New Blood whose name was changed in the English version.
- Reasonable Authority Figure: He genuinely appreciates Caduceus's help and supplies everything they need. While he does twist their arm to force them to treat his soldiers, he willingly negotiates terms with Markus over it.
Ramsey RamirezA former Major General who leads the Culuruma Liberation Front.
Voiced by: Jurota Kosugi (JP), Derek Stephen Prince (EN)The leader of Parnassus. Real name: Ray Kerensky.
- Death Equals Redemption: Defied by Markus, who pretty much throws his speech of penance back in his face and tells him to die already.
- Freudian Excuse: He went crazy because, after realizing his dream of becoming a doctor and coming back home to treat refugees, the army tried to have him assassinated. He then mistakenly assumed everyone in the world was like the people who betrayed him, and he decided that humanity's only true purpose was chaos.
- Load-Bearing Boss: Cardia was the only thing keeping him alive.
Characters from Trauma Team
Resurgam First Care
CR-S01 / Erhardt Muller
Voiced by: Takahiro Sakurai (JP), Nolan North (EN)
The protagonist of the Surgery mode in Trauma Team. A skilled surgeon sentenced to 250 years in cryogenic prison for his involvement in a biological terror attack at Cumberland College. He's lost his memory of who he is and has been allowed to redeem himself by performing operations for Resurgam First Care.A select few people have given him the Fan Nickname 'Numbers' as well.
- All There in the Manual: His real name is only revealed in the Japanese guidebook.
- Amnesiac Dissonance: Played with—he's aware of his previous crimes, but without any knowledge of why he committed them, this only drives him to become The Atoner. Later outright subverted when it turns out "his" previous crimes weren't even his in the first place.
- Badass Normal: Unlike his predecessors, who have the "Healing Touch", he has no special powers, but is still able to save patients' lives.
- Bishōnen: He has a really androgynous and handsome face.
- Catchphrase: Let this disease pass from this world... note
- Deceased Parents Are the Best: Subverted. His biological parents despised him for his "lack of emotion" and thought that he'd "kill them one day". His adoptive father, Albert Sartre, treated him better than his real parents.
- Determinator: If you're a patient of his, he will cure you. No exceptions.
- Human Popsicle: Kept within a refrigerated cell where the temperature is kept at zero degrees Celsius (AKA 32 degrees Fahrenheit, at which water freezes), in order to inhibit the growth of bacteria. Gabriel ironically points out that several forms of bacteria can still be grown at this temperature.
- Inconvenient Hippocratic Oath: It happened twice. The first time it happened, CR did not think to escape, although Ian thought he would. The second time, the trope is invoked word for word. CR sees Ian on the surgery side and the exit on the other. In both cases he chooses to help the patient.
- Instant Expert: Goes from 8 years in cryogenic prison to the operating room perfectly able to save lives, despite the fact that he was imprisoned at the age of 16 and would not have been allowed to practice surgery since then.
- Longer-Than-Life Sentence: After the Cumberland incident, CR-S01 was arrested and received a 250-year life sentence.
- Mr. Fanservice: He fits on all the qualifications.
- No Name Given: Was only by his prisoner number, CR-S01. Japanese materials note his actual name as Erhardt Muller.
- Not So Stoic: It's revealed in a bonus clip that the reason he doesn't smile is because he's spent so much time in a cold atmosphere that he actually has difficulty smiling. Said bonus clip features him practicing trying to smile and act friendly, with hilarious results.
- Parental Abandonment: Besides his parents, who died inexplicably, his adopted father vanishes at the same time as he is sent to prison.
- Troubled, but Cute: Which is hilariously subverted in his bonus scene.
- The Unsmile: He has a hard time smiling.
- When He Smiles: In the English guide manual/Japanese cover and his epilogue before the final episode, he is shown to be capable of smiling. Cue the squealing of fangirls.
Voiced by: Shizuka Ito (JP), Stephanie Sheh (EN)
The Protagonist of the Endoscopy mode in Trauma Team. The heiress to a wealthy Japanese family. She rebelled against her status by studying abroad in America as an endoscopist.
- Arranged Marriage: Tomoe's father nearly forces her into one in order to decide the clan succession. Luckily she manages to get out of it thanks to the timely intervention of Chief Patel & Gabe and her father's lung condition suddenly acting up.
- Catchphrase: "The way of honor." note
- Expy: Her relationship with Maria heavily mirrors Chie and Yukiko's.
- Lady of War: Erm, of endoscopy.
- Meddling Parents: Her father is one.
- Martial Medic: Training is the way of honor.
- Ninja Pirate Zombie Robot: She's one-third endoscopy specialist, one-third ninja, and one-third Samurai with crazy warping skills. Her Path of Honor is no joke, that's for sure.
- Non-Idle Rich: She's an endoscopist.
- Ojou: Heiress to a wealthy family.
- Rebellious Princess: Downplayed; rebellious non-royal heiress.
- Yamato Nadeshiko: Defied. She rebelled against her Japanese heritage by studying abroad in America. Ironically, however, she has the personality down pat; she defies the trope only because she's not committed to her family above all else.
Voiced by: Masashi Sugawara (JP), Dave Mitchell (EN)
The protagonist of the Orthopedics mode in Trauma Team. A former soldier in the US Special Forces with a strong sense of justice. He grew tired of taking lives and decided to start saving them as an orthopedic surgeon.
- Absolute Cleavage: A male example.
- Awesome McCoolname: HANK. FREEBIRD.
- Being Good Sucks: The central trope his story.
- The Big Guy: This is even the name of his first mission.
- Butt Monkey: He (as Captain Eagle) is hated by the public, no one at the hospital understands his mindset of good and humanitarianism, and Claire, his patient for whom he truly cares, is shot in a freak mall shooting (though she got better).
- Catchphrase: Rock solid! note
- Eyes Always Shut: To the point that he needs an Alertness Blink to signify that he's come out of his Catapult Nightmare.
- Gentle Giant: His defining character trait. He's The Big Guy, but he loves flowers, has a soft spot for a young patient of his, and performs operations requiring precision and caution rather than speed.
- Large Ham: Captain Eagle!
- Love Freak: I am the ambassador of love and justice!
- Made of Iron: Over the course of the game, Hank uppercuts a man through a ceiling, gets shot, and uses himself as a conduit to bridge two electrical cables. The only real casualty of all that is his clothing.
- Save the Villain: A gunman shoots several people in a shopping mall—one of them a friend of Hank's—and then leaps off a balcony and breaks his back after revealing that he was driven to his crime by despair over his apparently inoperable cancer. Hank not only protects the fallen man from the angry crowd, he personally operates on the man's damaged spine and extracts the cancerous tumors from his spinal cord.
Voiced by: Hitomi Nabatame (JP), Amanda Winn Lee (EN)
The protagonist of the First Response mode in Trauma Team. A hot-blooded paramedic who has quick reflexes and a desire to be a hero. However, she lacks patience with others and dislikes teamwork.
- Action Girl: Maria Torres has the most frantic gameplay of any character in Trauma Team, since she has to treat multiple patients at once. Her personality fits this. Bonus points for single-handedly stopping a bus from falling and crushing two other main characters.
- Ambiguously Brown: Her name implies some kind of Spanish or Hispanic descent.
- Expy: Look at this picture of Maria. Now look at this picture of Chie Satonaka. Hilariously, Amanda Winn Lee also voices a character in Persona 4: Chie's best friend, Yukiko.
- Ms. Fanservice: Her first appearance features her topless, with only a towel (barely) covering her breasts.
- Pre-Mortem One-Liner: "Suck on some antivirus you bastard! You won't kill off my town!"
- Parental Abandonment: Was at the same orphanage as Rosalia.
- Unwanted Assistance: In-Universe, Maria has this attitude towards her fellow paramedics.
Gabriel "Gabe" Cunningham
Voiced by: Keiji Fujiwara (JP), Travis Willingham (EN)
The protagonist of the Diagnosis mode in Trauma Team. An intelligent diagnostician with great powers of deduction. After years of work, he became desensitized to human life. His bitter attitude has caused him to be separated from his family.
- Berserk Button: In the episode 'The Simplest Truth', RONI finally pushes it. Seems like ever since an incident of his past, Gabe doesn't take kindly to be doubted or called out for not being honest with himself or others.
- Breaking the Fourth Wall: Does this in the epilogue. Depending on your view, it may also be a small Moment of Awesome or Heartwarming Moment.
- Chewing the Scenery: Gabe tends to be over the top normally, but pronounced during "Proud One", when Gabe is unable to run a diagnosis on Samuel, since the military is covering up what happened to him. Spyware within RONI prevents him from making any diagnosis, but he is able to have "friendly chats" and make "meaningless friendly observations." Taken to epic levels when Gabe gets Samuel to take his shirt off.
- The Chew Toy: Let's see here: He was almost hit by an arrow in Tomoe's storyline, got hit by a bus at a mall, his 'safe' landing got him in the trash at the last chapter, etc. The developers surely love messing with him, and for our amusement.
- Dreaming of Things to Come: Implied to have a dream about the Rosalia outbreak when he is first introduced.
- Dr. Jerk: A mild case compared to Victor of Second Opinion, but still.
- Expy: Admit it, you thought he was Spike when Atlus first announced the game.
- Finger Gun: In case the Spike Spiegel shout-out wasn't obvious enough, he strikes this pose when he's escaping on the helicopter.
- Lethal Diagnosis: Patents start out only suffering from one or two mild symptoms — such as a cough, fatigue, moments of disorientation, etc. — after being diagnosed are told they have some kind of tragic disease. Thankfully CR-S01 is more then a match for any disease.
- Meaningful Name: Dr. Cunningham is nothing if not cunning.
- No Smoking: He smokes a lot in the actual game, but his cigarette is absent in much of the publicity material.
- Suicidal "Gotcha!" Does this when trying to escape to create a diversion, complete with the Spike Spiegel Bang gesture.
- Team Dad: Sure, he has his own issues, but he has a heart-to-heart with just about every other member of the team at some point during their storylines.
Voiced by: Mayumi Asano (JP)
The chief of Resurgam, a cheery woman who can also be strict at times.
- Trademark Favorite Food: She seems to be really fond of Italian.
Voiced by: Shintaro Asanuma (JP), Orion Acaba (EN)
A nurse at Resurgam First Care.
Voiced by: Eri Kitamura (JP)
A nurse at Resurgam First Care.
Voiced by: Yurie Yamashita (JP)
Short for Rapid Operation Networked Intelligence terminal. A state of the art AI and disease database, which helps Gabe with his Diagnosis.
- The Anti-Nihilist: She becomes this following her Character Development.
- As You Know: Her programming requires her to give a short tutorial the first time she uses a feature, even if the user is a trained doctor.
- Mundane Utility: In Gabe's bonus scene, RONI is used as a cooking guide.
Voiced by: Jurota Kosugi (JP), Keith Silverstein (EN)
The FBI agent who captured CR-S01 years ago. Keeps an eye on him at all times.
- It's Personal: Subverted. His wife and daughter were killed in the Cumberland College attacks, but he watches over CR-S01 simply because it's his job, and has long since decided CR-S01 isn't the real culprit.
Voiced by: Rinko (JP), Laura Bailey (EN)
A private school student and a member of her school choir. She was admitted for diagnosis because of breathing problems.
- Fanservice: Minor example, but at one point in order to examine her, Dr. Gabriel Cunningham has to ask her to lift up her shirt so she can examine her breathing. The player gets to see her bra while she's doing this, and RONI has to scold Cunningham by pointing out that this is embarrassing the patient and Dr. Cunningham needs to be more tactful.
- Growling Gut: On the second examination her gut growls. Gabe notes that it is perfectly normal to be hungry.
- Ordinary High-School Student: Apart from her ambitious music aspirations, of course.
Voiced by: Kimiyoshi Kibe (JP), Harvey Atkin (EN)
The Assistant Secretary of the HHS. He collapsed in his house and was dragged in for diagnosis, to his annoyance.
- Chekhov's Boomerang: He aids Gabriel in letting him escape from the USAMRIID building while he faces charges for breaking the rules of the examination.
- Eyes Always Shut: Lampshaded and parodied. It causes problems for Gabe when he can't tell if his eyes are jaundiced.
- Fan Disservice: Gabe has to examine this insufferable man's Gonk body.Gabriel: 'This is not the most pleasant thing I've looked at recently...'
- Jerk with a Heart of Gold: All in all, he certainly has a big heart. Heck, you even get to see it when CR-S01 operates on him.
- Patriotic Fervor: He rarely misses an opportunity to loudly proclaim how much he loves his country.
Voiced by: Eri Nakao (JP)
A stock broker who previously had chronic renal failure and received a kidney transplant two months ago. She came in for a quick diagnosis and prescription thinking she just had a cold, but turned out to have much greater complications.
- Hello, Nurse!: Most of Gabe's comments when conducting a visual examination are about how attractive she is.
- Hot Librarian: According to Gabe himself.
- She's Got Legs: Hm... I don't think there's anything wrong with her legs. Nothing wrong at all...
- Something About a Rose: She wears a black rose brooch, and her bra also has a rose pattern on it. This foreshadows her Rosalia virus infection.
Voiced by: Hiromi Otsuda (JP), Yuri Lowenthal (EN)
Gabriel's son. He hasn't seen his father since he was very young, so he doesn't even recognize him. He suffered from gastric ulcers and underwent endoscopic surgery. He later had a relapse and tried to hide his symptoms because he didn't want anyone else to worry.
- Expy: If Gabriel is an expy of Spike, Joshua gets the spot for being a younger version.
- Strong Family Resemblance: The only way to point at him and say he's Gabriel's son is the hair.
Voiced by: Hana Takeda (JP)Gabriel's wife. She's never actually seen and only talks to him over the phone.
Voiced by: Daisuke Kirii (JP), Yuri Lowenthal (EN)
A researcher at USAMRIID. He began showing bizarre symptoms after running tests on an unusual set of bones found in Back Cove.
- Classified Information: He refuses to allow Gabe to do anything until his superiors give the go ahead.
- Expy: Some fans think he resembles Leon Kennedy.
- Fatal Family Photo: He mentions having a wife and daughter. As the diagnosis progresses, he gets much, much worse.
- Heroic Build: Gabe notes that he has a rather good-looking body. The Rosalia Virus just makes his body look worse by the minute.
Voiced by: Koutarou Nakamura (JP)
Tomoe's loyal retainer. Always watches over her carefully and is ready to support her, even in the face of her father.
- Badass Grandpa: To put it simply, he freakin' teleported to an airplane already flying over the clouds miles away from the ground.
- Battle Butler: Taken to insane levels, though his liege is just as good to fight.
- Bodyguarding a Badass: Tomoe can clearly hold her own against enemies, but Hanzou regardless looks after her.
- Crazy-Prepared: As expected of a very well-trained butler.
- Ninja Pirate Zombie Robot: He's part butler, part samurai, part ninja! Why can't all butlers be like that?
Voiced by: Atsushi Ono (JP)
Tomoe's father, and the leader of the Tachibana clan. He wants Tomoe to succeed the clan and disagrees with her decision to go overseas.
- Meddling Parents: Despite how successful and happy Tomoe is in her vocation as an endoscopy doctor, he really wants her to take over leadership of her family's clan.
- Shirtless Scene: Just to show off how imposing he looks like.
- Strong Flesh, Weak Steel: His skin is so tough that it can't be cut by a scalpel or pierced by a needle. In order to clear an airway, Hanzou had to use a sword.
Voiced by: Yuka Iguchi (JP)
A young lady who attempted to commit suicide. Hank Freebird saves her, but she only resents his efforts. Over the course of his story, Hank tries to teach her how wonderful the world really is.
- Broken Bird: It's revealed this is why she wants to commit suicide. Her mother's relationships went lousy, and ever since, Claire's never been able to trust men, and Claire's had a lot of relationships go sour so her distrust is magnified.
- Irony: Claire does in fact almost die when a crazed gunman shoots her at the mall...right after she finally wanted to live!
Voiced by: Hajime Iijima (JP)
A drug-smuggling kingpin also known as "Steady Hand Teddy". He came to America to make sales, but was apprehended by Captain Eagle. He swallowed his entire stash of narcotics in police transport and had to undergo endoscopic surgery.
- Not So Different: He makes this claim to Captain Eagle.
Voiced by: Matsuo Matsuo (JP)
A man who had a lung cancer operation four years ago. The cancer metastisized to his spine, and he was told it was inoperable. He lost hope and shot several people at a mall in his despair.
- Creator Cameo: His appearance and name are based on Hirotaka Mizuno, one of the game's programmers.
- Despair Event Horizon: His "horizon" was when he found out his cancer would kill him, and he felt that nobody else around him appreciate the lives they took for granted, which he considered an injustice since his own life would soon be cut short.
Voiced by: Yasuhiro Mamiya (JP)
The chief at the Cumberland Institute of Forensic Medicine. A warm-hearted older man who's lax on security, but serious about his work.
Voiced by: Mika Takashita (JP)
A cheerful young girl who lives next-door to the Cumberland Institute of Forensic Medicine. After bringing her sick cat Chloe to Dr. Kimishima, she starts playing around on the grounds often.
- Cheerful Child: Pity that she got bombed.
- Chekhov's Gunman: Alyssa's introduced as comic relief in Naomi's third in-game murder case, but she shows up again later and helps solve the mystery by discovering that a clock was broken...because there was something inside. The real murder weapon, to be precise.
Unknown voice actorsA college student that turned out to be being payed money to record voice threats for Sandra Lieberman, the Raging Bomber.
- Blackmail Backfire: He tries to blackmail Sanda who has him killed off in revenge, after abiding by his increased demands once.
- Death by Irony: Sandra, in order to orchestrate the above trope, had Eldred (vaguely) describe himself ("the next target will be a Caucasian male") in his final bomb threat before having him killed off.
- Loan Shark: Took out a massive loan to afford a vintage guitar.
- Tonight, Someone Dies: The theme of his bomb threats.
Voiced by: Rei Igarashi (JP), Laura Bailey (EN)
The "Raging Bomber" responsible for a series of bombings around Portland. Her M.O. was to send out an audio voice clip that, gleefully and arrogantly announced a description of her next target. Her first victim was an unnamed/unseen politician, then an unnamed/unseen singer, and then tennis player Aidan Posner. As it turns out, she had hired college student Stephen Eldred to provide voice talent for the threats (which would fool investigators into falsely presuming that she was a male); but when Eldred blackmailed Lieberman, she had Eldred unknowingly describe himself (a Caucasian male) on the final bomb threat before having him killed off for good. She was later killed in an explosion at an airport upon confrontation by authorities.
- Ax-Crazy: Courtesy of the Rosalia Virus.
- Blackmail Backfire:She killed Eldred in revenge for a blackmail attempt.
- Death by Irony: Having Eldred describe himself ("a Caucasian male") before sending the bomb to him.
- Criminal Mind Games: She sets up a quiz puzzle game in her suspected house for Naomi, and Naomi must put in an 8-digit number into each bomb without making too many mistakes. Make too many, and Game Over.
- Deadly Delivery: She delivers her bombs personally.
Mysterious Girl/Rosalia Rossellini
Voiced by: Sora Kuwakado (JP), Laura Bailey (EN)
A young girl seen "sleeping in bloom" in Trauma Team's opening, who soon begins appearing to Maria as a ghost. In reality, she is Albert Sartre's adopted daughter, CR-S01's adopted sister, and the young girl from the orphanage Maria saved when she was a kid. She harbors the "Rosalia Virus" and its corresponding antibodies, making her immune to virtually any disease. Was killed before the game began.
- Everyone Went to School Together: Was an orphan in the same orphanage as Maria.
- Famous Last Words: Can also be subverted as a Catchphrase as she says throughout Maria's story: Beginning...
- Meaningful Name: Could be a reference to Rosalia Lombardo, a two year old Italian girl who died in 1920 and whose corpse is now one of the most well-preserved specimens to this day.
- Nice Girl: From what we learn about her from the audio recordings we see of her, she seems to have been this. Her only wish was that her father, Albert Sartre, would succeed and cure everyone of disease. That she's a nice girl is also in stark ironic contrast to the fact that her deceased body almost caused an epidemic disaster.
- Sealed Evil in a Can: She harbors the incredibly lethal Rosalia Virus in her body, which is about the worst disease there is that can disintegrate anything inside the body and cause massive bloody hemorrhages, along with dementia for those who get affected by it.
- Sealed Good in a Can: Ironically, she also possesses the same antibodies that prevent her from succumbing to the same disease and any other illness in the world, which led Albert to retrieve those sought out antibodies but unfortunately got infected while doing it. The doctors are only able to retrieve the cure against the virus itself.
- Unwitting Instigator of Doom: Admittedly, it's more Albert Sartre's fault for shooting her, but Rosalia's body ends up being the originating point for a disease that then gets spread by monarch butterflies and almost wipes out Portland.
Voiced by: Yukihiro Misono (JP)
A professor of virology at Cumberland College. Vanished eight years ago after the bio-terror attack.
- Famous Last Words: My son... Forgive me... I was enticed by the Devil...!
- Meaningful Name: Could be a reference to Dr. Alfredo Salafia, the doctor who embalmed the corpse of Rosalia Lombardo.
- Mad Scientist: Mad, as in, mentally unstable. Played straight after being infected with the Rosalia Virus, which makes him lose his sanity and kill his daughter.
- Nice Job Breaking It, Hero!: Not only gets infected by the Rosalia virus trying to extract a cure from Rosalia's blood, he also manages to unleash the same virus to wreak mass terror when he tried to eliminate it.
- Unwitting Instigator of Doom: By shooting Rosalia near a place where monarch butterflies could get to her, Albert almost caused a terrible disease to wipe out Portland.