- Badass Creed: Jesse Custer learned his from his father, cribbed from John Wayne;John Custer: Don't take no shit off fools. Judge a person by what's in 'em, not how they look. An' you do the right thing. Be one of the good guys. 'Cause there's way too many of the bad.
- Badass Normal: Before being possessed by Genesis.
- Berserk Button: Be it animals, women, or children; DO NOT abuse the defenseless in his presence.
- Compelling Voice: due to being possessed by Genesis
- Eyepatch of Power: After he inexplicably loses his eye in the War In The Sun arc.
- Good Old Fisticuffs: Jesse's preferred fighting style, but can also be a Combat Pragmatist when the situation calls for it.
- Likes Older Women: Tulip is three years older than him.
- Literal Genie: All orders that Jesse issues using his "Word of God" power are interpreted this way.
- Red Eyes, Take Warning: He gets these whenever he uses the Word.
- Semi-Divine: As the result of having the "Word of God."
- Significant Anagram: Jesse Custer = Secret Jesus. Also, of course, his initials.
- Southern Gentleman: Has some elements of this, which are a source of endless entertainment for Amy and Tulip.
- Story-Breaker Power: "The Word" has the potential to be this, allowing Jesse not only to control someone's mind but their bodies as well such as when he caused his grandmother's enforcers to spontaneously combust just by telling them to "burn". However, Garth Ennis managed to avoid this by giving Jesse's power some very believable limitations. 1) They have to be able to hear him 2) They have to be able to understand him; making the word powerless against those who don't speak English, animals who aren't trained to respond to verbal commands, or those who are either deaf or can drown out his voice.
- Even the Girls Want Her: Amy does.
- I Just Want to Have Friends: As a child, the girls didn't want her because she liked boy things, and the boys didn't want her because she was a girl.
- Missing Mom: Due to Death by Childbirth.
- Straw Feminist: At her worst. Although she has been messed with a lot by men.
- The Determinator: Her hand is stabbed and stuck to a dashboard with a knife, but she still gets up to warn Jesse. And she later overcomes drug addiction with sheer willpower.
- The Gunslinger: But she's reluctant to pick up a gun again at the start of the story.
- Tomboy and Girly Girl: The tomboy to Amy's girly girl, though it's downplayed.
- Violently Protective Girlfriend: Mess with her man and you'll find out.
- Platonically for Amy.
- Car Fu: Attempted to drive a pickup into the Saint Of Killers, to no effect.
- Cursed with Awesome: His view of being a vampire.
- Does Not Know His Own Strength: He's well-aware most of the time, but in the past, smacked a woman across the face, breaking her jaw. The shock on Cassidy's face implies he didn't mean to go that far.
- Exposition of Immortality: He's a vampire and was made one during the Easter Rising in Dublin 1916 at the age of 16. He tells Jesse all about how he was turned and how he came to America and all the friends he's left behind and lost to old age through the years during a long conversation on top of the Empire State Building. Turns out he missed a few details, though.
- Good Thing You Can Heal: He takes decapitation in stride. This is used against him when Herr Starr, furious at the depth of his error in kidnapping Cassidy instead of Jesse, calls in his old friend Frankie to continuously shoot him to near-death, then wait for him to heal, then repeat.
- Karma Houdini: After all of the skeletons in his closet are revealed at how much a monster he is, he pulls it off by making a deal with God to capture Genesis. The last pages show him alive, with his curse removed. To be fair, he also demanded that Jesse would survive no matter what happened as one of the conditions. He also lets himself burn to "death" in the sunlight. Before that, he let Jesse beat the shit out of him. It doesn't really make up for everything he did in the past, but at least he doesn't get away without some pain.
- He's also going to have fun dodging the many enemies he made around the country when he was too strong to care, now that he's relinquished that super-strength.
- Our Vampires Are Different: Loves garlic, is unaffected by holy water and crosses and survives decapitation. He can also enter a church, can't turn into anything, and doesn't need invitations to enter anyplace. He doesn't even have any fangs, just regular teeth. The sun's a killer, though.
- "I tried (turning into a bat) once. Broke both my legs."
- Selective Obliviousness: Does this repeatedly, causing much grievous harm to other people. When Jesse calls him out repeatedly, he gets self-righteous.
- Suicide by Sunlight: Subverted. He appears to do this, but it turns out he already made a deal with God that will ensure his survival.
- Took a Level in Jerkass: Especially after the events of War In The Sun
- Who Names Their Kid "Dude"?: "So I got kind of a question. 'Proinsias'?"
- No Celebrities Were Harmed: Guy's a dead ringer for John Wayne.
- The Obi-Wan: Sort of became this after Jesse was possessed by Genesis.
Saint Of Killers
- Badass Boast: "There ain't worse than me in all of Hell. Go an' look." (Gunshot)
- Bottomless Magazines—His guns never need reloading, never miss, never jam, and with the exception of Cassidy, every shot is fatal.
- The Determinator: He never gives up. Ever.
- Did You Just Punch Out Cthulhu?: He shot the Devil in the face, and God as well.
- Exposition of Immortality: The Saint Of Killers got a four-issue mini-series all of his own to tell us about his mortal life in the Civil War and the terrible winter of 1878. He dumps a silver dollar with just that date on the counter of a bar in Gone To Texas, too.
- Implacable Man: Nothing can stop him.
- Instant Death Bullet: Nothing that gets shot by him survives. Unless they're already dead.
- Nigh Invulnerable: Minus the "Nigh." Nothing, and I mean NOTHING, harms him, not even having a nuke dropped on him.
- Quick Draw: The Saint of Killers can draw his guns faster than a man can see. He uses this to shut down Jesse's Word the second time they meet.Saint of Killers: "I'm bettin' I can clear holster 'fore your words hit the breeze, preacher. First twitch I see...that's what I'm gonna do."
- Rage Against the Heavens: After Jesse reveals to him his backstory.
- The Sixth Ranger: Becomes this to Jesse and his group after meeting the angel who sired Genesis in Vol 3.
- Ain't Too Proud to Beg: When The Saint finally cornered him, he begged for his life
- Big Bad: Everything, Genesis coming into Jesse, the war with the Grail, was all done as a long-winded way for God to see how loved and adored he was.
- Dirty Coward: If it would mean any possible harm to him, he won't take a chance facing it
- God Is Flawed: It is eventually revealed that all of the world's problems are caused by being created by a guy who grew up in total solitude (because there wasn't any universe yet!) and thus developed what could be considered a narcissistic personality disorder as well as any number of related mental problems.
- Jerkass God: The world's a shithole because God's a dick.
- Let's Get Dangerous: You really do not want to piss Him off.
- Pet the Dog: He really didn't have to keep up his end of the bargain and Resurrect Cassidy and Jesse but he did anyway.
- Butt Monkey: Undergoes a Humiliation Conga like no other. At the time of his death, this is the sum total of his injuries (deep breath:) One of his eyes is blind, one of his ears was shot off, a scar was carved over his head making it look like a gigantic penis, cannibals ate his leg and a rottweiler bit off his genitals. Oh, and he's bald and has a harsh voice, too. Since childhood. He literally becomes this when he is anally raped by Bill Glover.
- Compensating for Something: After losing his genitalia Herr Starr feels the need to get a bigger gun. And then stand in front of a mirror with it, muttering "Doomcock. Doomcock."
- In a way, that turns out to be his downfall: if he was still using his old nine-millimeter pistol, he wouldn't have run out of ammunition in his final gunfight with Tulip.
- Determinator: Hops his way out of the desert on one leg, falling every few steps.
- Roaring Rampage of Revenge: Got his scar, voice, and baldness from a childhood incident where a gang of schoolboys cut his eye out with a piece of glass. They all ended up dead before his tenth birthday. This incident got him the job as the Sacred Executioner of the Grail.
- The Starscream: To D'Aronique, who thinks being Genre Savvy about this will make using him anyway less risky.
- Everyone Calls Him Barkeep: We never do learn what he was called before he took on the name "Arseface". All we can say for sure is that his last name is probably Root. The AMC series reveals his real name to be Eugene.
- Happily Failed Suicide: Arseface tried to kill himself because he was sad and lonely, and his idol Kurt Cobain and his only friend had both just killed themselves and the friend had told him to do the same. After the failed suicide attempt, he does all he can to turn his life around, but can never get away from his face being horribly mutilated by the shotgun blast that so fortunately missed his brain.
- Nausea Fuel: Was this In-Universe to most people he met, causing them to involuntarily vomit upon seeing him.
- The Dreaded: is this to his own people as well as major world leaders, requiring them to call him daily and thank him for allowing them to remain in power. Starr himself, despite his revulsion towards D'Aronique, has good reason to be scared shitless of him.
- Evil Uncle: Jesse's grandmother Marie L'Angelle was Allfather D'Aronique's aunt. It turns out that one of the reasons the Grail leadership supported Starr's pursuit of Jesse was because D'Aronique wanted to punish Jesse for killing his "Aunt Marie".
- Genre Savvy: Despite his appearance, D'Aronique is not only a sadist but is ruthlessly clever, knowing that Starr intends to assassinate him but keeps him close anyway to better keep an eye on him and allowing him to pursue Jesse so he could pursue his own retribution against him.
- Villainous Glutton:Marseilles: God he (D'Aronique) disgusts me, what do you suppose he's thinking about?Starr: His favorite subjects-mass murder and big pies.
- The Dreaded: Was this to Jesse his entire life. Just hearing her name mentioned in the first volume was enough to make him freeze in terror.
- Would Hurt a Child: Not only cruel to Jesse- her idea of diciplining Jesse as a child was to lock him inside of a coffin and submerging it at the bottom of a river with only an airhose to keep him alive, but was to his mother, too.
- Kick the Son of a Bitch: After all of her Kick the Dog moments, watching her flaming corpse getting blasted into the sky when the fire Jesse set to her house blows up her oxygen tanks is EXTREMELY gratifying.
- The Dragon: To Marie
- Evil Mentor: To Jesse
- Even Evil Has Standards: Is completely loyal to Marie and hates those who don't stand by their own.
- Anti-Hero: Along with T.C. in the one-shot "The Good Old Boys."
- Anything That Moves: And in some cases, anything that doesn't.
- Badass Normal: He and Jody show an uncanny knack for surviving in the swamp, if need be.
- Co-Dragons: With Jody
Jesus De Sade
- Anything That Moves: Quite literally. In his first appearance he was about to have intercourse with an armadillo.
- Depraved Bisexual: Well, Depraved Omnisexual may be a better way to put it.
- Politically Incorrect Villain: To the point that even some of his fellow Klansmen were disturbed.
- The Atoner: Comes to Salvation to help atone for the damage his brother, Odin, caused.
- Cool Old Guy: Offers Arseface a job simply because Lorrie asked him to.
Jacob "Jake" O'Hare
- Cluster F-Bomb: Somewhat averted, as he never really drops the f-bomb:"Damn wife died. Damn baby's a girl."
- Cuteness Proximity: After meeting his daughter for the first time:"Aw, so you're a girl. That needn't be so bad."
- Papa Wolf: Even though he wanted a son at first, he never failed to stand up for his daughter when necessary.
- Verbal Tic: "Damn" among his friends, although he avoids it when speaking to Tulip.
- Affably Evil: Established in his first appearance where he's seen playing cards with the Angel of Death