!!Vincent Law
->Voiced by Creator/KojiYusa (JP), Creator/LiamOBrien (EN)
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* [[spoiler:AmnesiacGod]]
* AntiHero: He starts off as a weak-willed, low-status immigrant just trying to make good for himself.
* BadAss: He doesn't realize it for a long while, but once he does the gloves come ''off''.
** BadassCreed: Are the last lines of the series, but damn - it's a badass way to close a series.
--> '''Vincent''': "[[spoiler: I am Ergo Proxy - the agent of death.]]"
* [[spoiler:BecomeARealBoy]]: Like Pino in this respect [[spoiler: and also why he hopefully will also survive on contact with sunlight]].
* BewareTheNiceOnes
* BerserkerTears: Vincent is prone to these while in proxy form. Usually while killing another proxy.
* BrokenTears: Several times over the course of the series. Most noteable is when Vincent is lying on the ground weeping after Proxy One forces him to face the fact that he is a proxy.
* TheChosenOne: Hoody said that Vincent was this to the rest of the commune dwellers when they started to suspect him. [[spoiler: Then it ended up sort of being true...]]
* {{Determinator}}
* DoomMagnet: [[spoiler: Well, he is the agent of death.]]
* EyesAlwaysShut: Starts out this way, but they open after he becomes less meek.
* FanservicePack: Over the course of the series, he gets better looking and even seems to grow several inches taller.
* HorrifyingHero
* TheKirk
* [[spoiler:JekyllAndHyde: Initially, Ergo Proxy comes across as his SuperpoweredEvilSide and is a distinct entity from the meek Vincent.]]
* NiceGuy
* PapaWolf: Do NOT mess with Pino. Seriously, don't.
* [[spoiler:SplitPersonalityMerge]]: Something like this at the end of the series [[spoiler: as he finally has both Ergo Proxy's powers and Vincent's personality.]]
* TookALevelInBadass: Several, even!

!!'''Re-L Meyer'''
->Voiced by Rie Saito (JP), [[Creator/MeganHollingshead Karen Thompson]] (EN)
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* ActionGirl
* AntiHero: She's a bit cold emotionally and has a definite mean streak, but there's no question she's one of the good guys.
* BadassLongcoat: Arguably subverted; despite her competence at her job, she's nowhere near as badass as she presents herself, a fact that becomes apparent [[spoiler: after leaving Romdeau. This is bitterly lampshaded by Iggy after he contracts the Cogito virus, when he [[TheReasonYouSuckSpeech calls her out]] on acting like a badass government agent when she's really kind of a spoiled brat. Just how accurate this is is ambiguous, however; it could just be the rantings of a wounded friend taken for granted for too long.]] And despite all that, she still remains tough as nails throughout ensuing events.
* {{The Comically Serious}}
* DeadpanSnarker
* DefrostingIceQueen: Hell of a slow thaw, though.
* EeriePaleSkinnedBrunette: Everyone else has normal skin tones, whereas Re-l is straight black and white.
* EmotionlessGirl
* {{Good is Not Nice}}
* {{Goth}}: She's something of a [[DeadpanSnarker snarky]], gloomy goth, dressing in all black and wearing lots of eyeshadow.
* IntelligenceEqualsIsolation: She chafes at Romdeau, where much of the human population are so coddled and helpless that they're effectively automata.
* JerkWithAHeartOfGold
* MsFanservice: Not as much as other female characters in anime, but is particularly prominent when [[spoiler:Ergo Proxy has flashbacks of their first meeting in her bathroom.]]
** Of course, given that [[spoiler: the flashback is from his POV, it's combined with MaleGaze.]]
* TheSpock
* SuperOCD: It's been speculated that Re-l might have OCD, judging from the way she conducted an earlier investigation of Vincent's room (she lined up a cup on a stand in the mirror image of another) and the way that she behaved in episode 16. However, the former case could be the result of years of strict government training and the latter a result of CabinFever.
* {{Tsundere}} or SugarAndIcePersonality
* UsedToBeASweetKid: Judging from some old videos from Daedalus, Re-l seemed to be pretty cheerful growing up. Then she just became... [[{{Goth}} gloomy.]]
* [[WellDoneSonGuy "Well Done, Granddaughter" Chick]]: In the end, Re-l just wants her grandfather's love and recognition.
* WhenSheSmiles: At the end of episode 16, upon seeing Re-l give a true smile, Vincent is seen blushing.


!!'''Pino'''
->Voiced by Akiko Hajima (JP), Rachel Hirschfeld (EN)
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* [[BecomeARealBoy Become A Real Girl]]: See MeaningfulName. It's kind of implied that this does happen in a literal sense, and it's necessary for the series to have a happy ending of any kind [[spoiler: as otherwise, she'd be killed by ultraviolet light like all autoreives]].
* CreepyChild: Before Character Development.
* TheMcCoy
* MeaningfulName: She shares a name with Pino of ''Manga/BlackJack'', and for both of them the name alludes to Literature/{{Pinocchio}} and their status as an artificial child.
* RobotGirl

!!'''Iggy'''
->Voiced by Kiyomitsu Mizuuchi (JP), Creator/TravisWillingham (EN)
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* [[spoiler: AIIsACrapshoot: DoubleSubverted. He gets infected with the Cogito virus when [[OffingTheOffspring Romdeau's ruler sics his Autoreivs on Re-L,]] but actually keeps his sanity for a time. Then Re-L orders him to go back to Romdeau on his own, [[SanitySlippage at which point it kicks in for real.]]]]
* [[spoiler: AlasPoorScrappy: InUniverse. Re-L clearly doesn't like being around him for much of his screentime, on account of believing him to be JustAMachine and her [[ArchnemesisDad grandfather's spy.]] It's only after [[WhatTheHellHero he rails on her]] [[AIIsACrapshoot under the effects of the Cogito virus,]] and has to [[ICannotSelfTerminate be put down]] [[DeathEqualsRedemption after saving her life]] that she shows any sincere affection towards him.]]
* [[AmbiguouslyGay Ambiguously Gay.]] Later episodes reveal that Re-l deliberately chose him to sound this way.
* JekyllAndHyde: [[spoiler: [[ICannotSelfTerminate As he lays dying in Re-L's lap,]] he continually shifts between his [[NiceGuy old personality,]] who [[TearJerker begs Re-L to forgive]] [[MyGodWhatHaveIDone him and not to hate him,]] and his [[{{Jerkass}} Cogito]] [[{{Yandere}} infected]] [[MoodSwinger self,]] who angrily [[NeverMyFault blames her for getting him killed.]] The possible implication being that even after developing sentience, it was the [[GollumMadeMeDoIt Cogito infection causing him to attempt his kidnapping and murder]] [[TragicMonster not Iggy]]]]
* JerkassHasAPoint: [[spoiler: Subverted. [[SanitySlippage After completely losing it,]] he chews out [[WhatTheHellHero Re-L essentially for thinking herself more Badass than she really is]], but whether one agrees with him or not, his "plan" [[WhatAnIdiot (consisting of dragging Re-L back to Romdeau, where she'll likely be arrested and/or executed,]] [[ItCanThink and he'll likely be decomissioned for being infected)]] [[StepThreeProfit is so unbelievably half-baked,]] that his only response is to ignore Re-L for calling him out on it. [[MoralEventHorizon And that's not even getting into]] [[MurderTheHypotenuse trying to kill Vincent]] to keep Re-L for himself, basically decimating whatever point he could possibly have.]]
* [[spoiler:KilledOffForReal]]
* NiceGuy: [[{{Camp}} Peppy]], supporting, optimistic, and [[BigBrotherInstinct protective]], hard to see why [[JerkWithAHeartOfGold Re-L dislikes him at first.]] [[spoiler: [[AIIsACrapshoot Until]] [[SanitySlippage later]] [[TookALevelInJerkass that is.]]]]
* [[spoiler: {{Yandere}}]]: Becomes this later in the series [[spoiler: after getting the Cogito Virus]].

!!'''Raul Creed'''
->Voiced by Hikaru Hanada (JP), Creator/PatrickSeitz (EN)
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* AntiHero: He means well. Really.
* [[spoiler:AxCrazy: Post SanitySlippage.]]
* BadassLongcoat
* {{Break the Haughty}}
* DarkMessiah
* DeadpanSnarker
* {{Determinator}}
* InspectorJavert: Shades of it anyway.
* ItsPersonal
* [[spoiler:KilledOffForReal]]
* NietzscheWannabe
* [[spoiler:SanitySlippage]]
* {{Tall Dark and Snarky}}
* TheStoic: Until [[spoiler: he goes [[Main/{{AxCrazy}} completely insane]]. ]]
* WellIntentionedExtremist: Starts as this. [[spoiler: [[MotiveDecay Descends into a]] WoobieDestroyerOfWorlds, before [[HeelRealization coming to his senses]] [[AlasPoorVillain in his final moments.]]]]

!!Daedalus Yumeno
->Voiced by Creator/SanaeKobayashi (JP), Creator/YuriLowenthal (EN)
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* CreepyMonotone
* [[spoiler:KilledOffForReal]]
** [[spoiler: DroppedABridgeOnHim]]
* MadScientist
* StalkerWithACrush
* {{Yandere}}


!!'''[[spoiler: Proxy One]]'''
->Voiced by Creator/HochuOtsuka (JP), Creator/DameonClarke (EN)
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* BigBad
* LargeHam
* GreyAndGrayMorality / EvilVersusEvil: [[spoiler: He's pretty much responsible for much of the story's events, and ultimately, Romdeau's destruction, but everything he's done is in retaliation for what the [[HumansAreBastards Crea]][[BiggerBad tors]] [[WhatTheHellHero have done]] [[YouHaveOutlivedYourUsefulness and are planning to do.]]]]
* TheManBehindTheMan
* ManipulativeBastard
* {{Ubermensch}}: Fits the bill. [[spoiler: He was created to heal the planet Earth, and then die so that it would be handed over to his Creators. Proxy One essentially decided "Fuck that", and instead rejected their plans and ideals, opting to create a proxy who could survive sunlight i.e. Ergo Proxy, both to ensure at least one Proxy survived the genocide, and as a big, fat screw you to the Creators.]]
* WoobieDestroyerOfWorlds: [[spoiler: He's part of a species of immortal demigods who are intended to [[YouHaveOutlivedYourUsefulness self-destruct when planet Earth heals up,]] as [[UngratefulBastard thanks for having fixed the mess their creators started in the first place.]] [[TurnedAgainstTheirMasters Understandably, he's a]] [[RageAgainstTheHeavens bit upset.]]]]
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