[[folder:Shotaro Kaneda]]
[[caption-width-right:250:"''[[MemeticMutation Tetsuooooooo!]]''"]]
->Voiced by: Creator/MitsuoIwata (JP), Creator/CamClarke (EN, Streamline dub), Creator/JohnnyYongBosch (EN, Animaze dub), Creator/IrwinDaayan (LA, first and second dubs), Sergio Zamora (SP, first dub), Nacho de Porrata (SP, second dub), Ángel de Gracia (SP, third dub)

* AdaptationalHeroism: While he's by no means perfect in the movie either, many of Kaneda's nastier traits from the manga are suspiciously absent from the movie.
* AffectionatePickpocket
* AMFMCharacterization: In the manga, there's a scene where Kaneda sings "Starry Starry Night" to himself in the bathroom.
* BadassBiker: Stands out as this because of his CoolBike and riding skills.
* BadassNormal: [[spoiler:Kaneda was taking on a fully powered Tetsuo with a laser gun and ''winning.'' He actually would've pulled off killing him, something even the entire military was failing at at that point, but the gun ran out of energy.]]
* BigEater
--> '''Kei:''' "Is eating all you do?"
* ButtMonkey: Gets the most amount of punishment while never suffering anything really irreversible.
* CharacterDevelopment: Goes from a selfish, womanizing jerk to a genuine hero who cares deeply for the woman he loves.
* CharacterizationMarchesOn: At the beginning of the manga he's a complete dick, but becomes a little more tolerable by the end.
* ChivalrousPervert: He's a total pervert to Kei at the start, but later grows fond of her.
** Averted big time, however, with the way he treats his first girlfriend in the manga. He doesn't really care about her much and only uses her for sex and to score drugs (she's doing some kind of internship with the school nurse) and when she tells him he may have gotten her pregnant he ''laughs about it''.
* {{Determinator}}: Throughout the story, and especially in the final battle with Tetsuo.
* DisappearedDad: He IS one (assuming his ex and unborn child survived the events of the manga, which is hardly a guarantee).
* {{Expy}}: He is named after and physically based off of the main character of Tetsujin 28-go, though their personalities are nothing alike.
* IconicOutfit: The red motorcycle jacket with the Capsules' logo on the back.
* JapaneseDelinquent: He fights, does drugs and runs a biker gang. And he's still in high school.
* {{Jerkass}}: He starts out as a big one, especially in the manga but matures as time goes on.
* LastNameBasis: Always goes by Kaneda.
* NoOneShouldSurviveThat: Kaneda is by far the luckiest character in the storyline. In fact, it could be argued that [[spoiler:he ''didn't'' survive the obliteration of Neo Tokyo]] and only pulled through because of an odd application of the TimeyWimeyBall.
* OnlyFriend: To Tetsuo in their childhood.
* PinballProtagonist: He's not exactly the biggest player on the manga, and even gets PutOnABus [[spoiler:after the {{time skip}}]].
* SupportingProtagonist: In the movie.
* UnscrupulousHero: Sure, he saves Neo-Tokyo, but he's still an obnoxious delinquent.

[[folder:Tetsuo Shima]]
[[caption-width-right:250:"''[[SayMyName Kanedaaaaaaaa!]]''"]]
->Voiced by: Creator/NozomuSasaki (JP), [[VideoGame/LeisureSuitLarry Jan Rabson]] (EN, Streamline dub), Joshua Seth (EN, Animaze dub), Genaro Vásquez (LA, first dub), Creator/BenjaminRivera (LA, second dub), Creator/AlbertTrifolSegarra (SP, first and third dubs), Carlos Lladó (SP, second dub)

* AbstractApotheosis: To some degree, by the end, Tetsuo becomes more the personification of his own power than the character he began as.
* AdaptationalHeroism: While he isn't a hero by any definition in the movie either, Tetsuo is significantly more sympathetic and takes a much longer time to [[JumpingOffTheSlipperySlope take a flying leap off the slippery slope]] than he did in the manga.
* AGodAmI: To some degree.
* AscendToAHigherPlaneOfExistence: [[spoiler:Implied to be Tetsuo's fate in the end of the anime film, as his enormous psychic abilities led to him being the god of a new universe.]]
* ArtificialLimbs: He loses an arm to the KillSat then telekinetically builds himself a robotic one out of pieces of scrap metal.
* AwLookTheyReallyDoLoveEachOther: With Kaori in the manga. Even if Tetsuo is cruel towards her, they still let each other sleep on their laps and [[spoiler:loses control over his power after Kaori dies.]]
* AxCrazy: Moreso in the manga.
* BadassCape: In both manga and the anime film.
* BerserkButton: He will get angry when somebody treats him as if he is weak.
* BewareTheSuperman: A fair few undertones of this, given that his extraordinary power ends up destroying the lives of nearly everyone he comes into contact with.
* BigBad: While Tetsuo starts off just as confused as everybody else, he becomes the main antagonist eventually.
* BlobMonster: His mutated form is a flesh version of this.
* BodyHorror: One of the most iconic scenes from the anime involves this. Due to a SuperPowerMeltdown, his body starts to mutate into the epitome of this trope. He also suffers from this in the manga, but for a long time while trying to regain control.
* BridalCarry: A tragic version. [[spoiler:Tetsuo carries Kaori this way all over Neo-Tokyo after she is shot to death by his own supporters.]]
* ClippedWingAngel: His fetus-thing transformation is terribly strong, but he doesn't have any control of it so attacks at random, making it less dangerous. Also, it slowly and painfully kills him.
* DespairEventHorizon: [[spoiler:After Kaori is killed. He goes to Akira's chamber without clear intentions, but seems to be tired of everything and loses control of his powers by the last time]].
* DrivenByEnvy: His motivation for lashing out against everyone and even his childhood friend Kaneda.
* EldritchAbomination: The sheer amount of BodyHorror caused by his SuperpowerMeltdown at the end turns him into one that consumes anything it touches. [[spoiler:The only thing that could stop him was Akira's resurrection and the subsequent birth of a new universe, which definitely adds Eldritch points.]]
* EmpoweredBadassNormal: After discovering his powers.
* EvilAlbino: In the final volume Tetsuo begins to mutate but is able to pull himself together. In his reconstituted form he appears unnaturally white because he lost all pigment in his skin and hair.
* FetusTerrible: His mutated form resembles this.
* ForeheadOfDoom: Gains a very noticeable one after he gains powerful psychic abilities.
* FreudianExcuse: Poor Tetsuo had to deal with bullies of various sorts his entire life until he discovered his powers and there is also the fact that [[spoiler:he was rejected by his parents and left in an orphanage]].
* FromNobodyToNightmare: From an insignificant bullied kid with a severe inferiority complex to an insane teenage monstrosity with godlike psychic powers lashing out at everyone who put him through hell. [[spoiler:And that's not getting into the BodyHorror parts...]]
* GoingColdTurkey: Tetsuo goes through agonizing withdrawal to quit the pills the scientists gave him [[spoiler:to keep him from losing control of the Power]].
* GoneHorriblyRight: The military succeeded ''too'' well in unlocking Tetsuo's powers.
* HealingFactor: To wit, Tetsuo survives [[spoiler:multiple shootings, an overdose of medicine, an assassination attempt by Kei, his arm blown off by a KillSat, gassing with a specially-engineered biological weapon, and a missile landing on him]]. Dr. Onishi and the Colonel discuss his remarkable resilience.
* JapaneseDelinquents
* LimaSyndrome: In the manga, Tetsuo comes to feel some degree of sympathy for Kaori, the girl he had abducted and tried to make into his sex slave, even letting her take a nap with her head on his lap.
* NoSell: [[spoiler:When a Japanese-American soldier tries assassinating him with a new experimental weapon, it not only completely fails to take out Tetsuo, but also ''heals him'' from the SuperpowerMeltdown he was suffering from]].
* OrphansPlotTrinket: [[spoiler: As a child, Tetsuo has a locket with a woman's picture in it and he tells people it's a keepsake from his mother. He actually found it in the street and just pretends it's her in order to feel some connection with his parents]].
* OutOfTheInferno: Right before he starts fighting the military in the movie.
* OvershadowedByAwesome: Tetsuo is a deconstruction of this, he developed a massive inferiority complex over how Kaneda excels over him. So much that he became the TragicMonster he is now.
* ParentalAbandonment: [[spoiler: He did have parents, once upon a time, but it's implied they dumped him in an daycare orphanage and never came back for him. No wonder he became so screwed up later in life]].
* PersonOfMassDestruction: At one point Colonel Shikishima refers to him as "another Akira".
* PowerMakesYourHairGrow: During the story, his hair becomes longer and more spiky. Inverted when he becomes a [[BodyHorror huge flesh blob.]]
* PsychoticSmirk
* PutOnABus: In the manga. [[spoiler:After getting his arm shot off by the SOL satellite at the end of the second volume, Tetsuo flies off and is not seen again until the end of Volume 3.]]
* RealityWarper: Tetsuo became powerful enough to create his own universe in an alternate dimension and merged with it in the end, therefore he counts.
* SanitySlippage: Suffers from this as time goes on.
* ScreamingWarrior: Throughout the movie when he gains his powers and starts attacking anyone in his way he lets out a giant scream.
* ShadowDictator: Akira is made a ruler of the empire in the manga, but he nothing more than a [[PuppetKing puppet]]. Tetsuo is the one running the game behind the scenes.
* ShrinkingViolet: Tetsuo was very introverted as a child.
* SlasherSmile:
* TheSociopath: Reads like a checklist for Antisocial Personality Disorder.
* SorcerousOverlord: Tetsuo after the third book. Just replace magic with psychic powers.
* SuperpowerMeltdown
* [[BulletCatch Tank Ammo Catch]]: Tetsuo does this ''with his mind'' in the movie.
* TeensAreMonsters: A great example.
* TookALevelInBadass: Thanks to his newly awakened powers!
* TragicMonster: In both continuities.
* UnstoppableRage:He causes a lot of destruction when he rampages through the city.
* VillainousBSOD: [[spoiler: After Kaori is shot to death in the manga, Tetsuo goes on a massive RoaringRampageOfRevenge]].
* VillainProtagonist: While Kaneda is the "good guy" of the story, Tetsuo drives the plot far more, and ultimately focuses around the development of his powers and his descent into villainy.
* WhosLaughingNow: To Kaneda.
* WithGreatPowerComesGreatInsanity: Tetsuo goes crazy due to his severe inferiority complex being combined with psychic power beyond his wildest dreams.
* WoobieDestroyerOfWorlds: Naturally.

[[caption-width-right:350:"What if there were some mistake and the progression went wrong, and something like an amoeba were given power like a human?"]]
->Voiced by: Creator/MamiKoyama (JP), Lara Cody (EN, Streamline dub), Creator/WendeeLee (EN, Animaze dub), Mónica Manjarrez (LA, first dub), Laura Ayala (LA, second dub), Mercedes Diemand-Hartz (SP, first dub), Creator/CarmenAmbros (SP, second dub), Esther Solans (SP, third dub)

* ActionGirl: Shown when she fights Tetsuo.
* CharacterDevelopment: Begins the manga as a hardened militant who has no problem killing to achieve her group's objectives. As the story progresses, she turns away from violence and tries to spare lives when she can.
* ExtraordinarilyEmpoweredGirl: [[spoiler:While she shows traces of this in TheMovie, it's never explained why the espers chose her out of all the other people in Neo Tokyo, The manga explains that she herself has powers; but her powers are that of a medium]].
* LaResistance: A member of this.
* MyGodWhatHaveIDone: In the movie, she shoots a soldier to save Kaneda, and completely freezes up afterwards. It's implied that she's never killed before.
* PowersViaPossession: By allowing the Espers to possess her, Kei is able to use all their powers.
* WillingChanneler: What her power is. She can serve as a spiritual conduit for the Espers, allowing her to use their PsychicPowers and do things the Espers themselves cannot. In the manga, it is shown more explicitly; at one point, she had to cleanse herself in a ritual bath to get rid of all physical and mental impurities before using her powers.

[[folder:Colonel Shikishima]]
->Voiced by: Taro Ishida (JP), Tony Mozdy (EN, Streamline dub), Creator/JamiesonPrice (EN, Animaze dub), Ricardo Brust (LA, first dub), Mario Sauret (LA, second dub), José Luis Sansalvador (SP, first dub), Ramón Rocabayera (SP, second dub), Juan Carlos Gustems (SP, third dub)

* ActionSurvivor: In TheMovie, he is one of the only four survivors that are shown. He also survives everything in the manga, though not unscathed.
* TheAtoner: In the later part of the manga, after he sees first hand what his evil plans have done to the nation he swore to protect.
* BadassMustache
* BloodKnight: While he is the OnlySaneMan of the military, Shikishima does not hesitate to enjoy a good fight, as being a soldier is the one thing he can do best. In the latter half of the manga, after his organization is gone and he is isolated from the rest of the military due to Neo Tokyo's destruction, he engages in numerous battles himself.
* ColonelBadass: In the anime, he tries taking on a rampaging Tetsuo [[spoiler:after the guy underwent insane amounts of BodyHorror]], and turns out to be the only person in Neo-Tokyo's government not to be heavily corrupt. In the manga, he survives [[spoiler:Akira's destruction of Neo-Tokyo]] and once he sees the consequences of his actions, he starts owning up like a man and becomes a valuable ally to Kaneda and friends. There's a reason why he has the word "Colonel" in his name.
* LastNameBasis: His full name is Colonel Shikishima, but he's referred to by rank.
* OnlySaneMan: The movie can give this impression of him, given that he is dealing with heavily corrupt politicians on one side and researchers who [[ForScience don't seem willing to balance the potential benefits of their research against the demonstrably severe risks.]] He's trying to run the research program while also trying to minimize the risk to the surrounding city and the world.
* PapaWolf: To the Espers, and also to Kaori in the movie. Because Tetsuo was advancing on her, he was the only one aside from Kaneda to score a hit with his gun.
* TookALevelInBadass: After the {{time skip}} in the manga. Before, he's a very angry EliteMook who spends his whole time shouting conflicting orders. After, he's a much more thoughtful and outright heroic character who shows that he's a very badass fighter who's not to be messed with as time goes on, leading up to him attempting to take out Tetsuo head on.
* WellIntentionedExtremist: He's willing to do anything to protect his country, including [[spoiler: starting a secret project that uses psychic children as political/military weapons, and using a government-owned laser satellite to kill a psychic teenager. He also overthrows the government in a military coup right before Neo Tokyo's destruction]].

* AmbiguousDisorder: His behavior in the manga heavily resembles nonverbal autism, but it is never given an official explanation.
** In one of the last chapters its explained that awakening shredded his personality and that the same could happen to Tetsuo.
* AscendToAHigherPlaneOfExistence [[spoiler: In the anime. The big explosion that left that massive crater was caused by him ascending into an energy form. E=mc^2 and all that. In the manga, he also does this with the Espers, though the process is less confusing.]]
* BerserkerTears: [[spoiler: Sheds these as he destroys Neo-Tokyo after witnessing Takashi's death]].
* BewareTheQuietOnes: He's a small kid who doesn't talk much, but he was the one who obliterated the original Tokyo all by himself. [[spoiler: And he does it again to Neo-Tokyo after Takashi is shot dead in front of him]].
* BreakTheCutie: [[spoiler: Witnesses Takashi being brutally shot in the head by Nezu shortly after being released from cryogenic sleep. Being connected to the Espers via a PsychicLink didn't help matters, either]].
* BrainInAJar: Only in the movie. [[spoiler:And only temporarily]].
* CreepyChild: Can come across as this due to his blank facial expressions, his lack of speech and emotional reaction to external stimuli. Oh, and he's one of the most powerful psychics in the manga.
* DeadAllAlong[=/=]PosthumousCharacter: [[spoiler:By thirty years in the movie. Subsequent resurrections notwithstanding.]]
* DyingAsYourself: [[spoiler: In the final book of the manga, Akira is shot by Ryu. Subverted in that he doesn't die, but he manages to recognize Masaru and Kiyoko long enough to stop Tetsuo and ascend to a higher plan of existence with his friends]].
* [[EmotionlessGirl Emotionless Boy]]: For most of the manga [[spoiler: until the very end]].
* GodEmperor: In the manga, Tetsuo takes advantage of Akira's resurrection from cryostasis and declares the Great Tokyo Empire which worships him as a god. Subverted, since Akira doesn't really care about ruling and lets [[ShadowDictator Tetsuo]] run the cult of personality.
* GoneHorriblyRight: [[spoiler: Akira was created by the Japanese government as a project to create psychic children to use as military/political weapons. They succeeded, but he grew beyond their control and were forced to seal him underground]].
* HolyBackLight: [[spoiler: How he comes back in the anime]].
* HumanPopsicle: In the manga, he is placed into cryogenic storage while still alive. Tetsuo later thaws him out.
* NeurodiversityIsSupernatural: In the manga, he can barely speak or do anything by himself (Kaori has to feed him), but he's still the most powerful psychic in existence. However, it was never explained whether or not he was like that before the government experimented on his brain.
* PersonOfMassDestruction: Do we need to explain what he did to the original Tokyo?
* PsychicChildren: A former member of the Espers, except cryogenics allowed him to stay young while the Espers themselves had their bodies aged prematurely from drugs and experimentation.
* PsychicLink: [[spoiler: With the Espers, which leads to Neo-Tokyo's destruction when he "feels" Takashi being killed by Nezu. Then later on he establishes one with Tetsuo near the end]].
* SchrodingersCast: [[spoiler:Alive throughout the manga, but DeadAllAlong in the movie (though he gets better.)]]
* SealedEvilInACan: Although he's not so much "evil" as he is an autistic and emotionally broken child with enormous psychic powers.
* StrappedToAnOperatingTable: [[spoiler: This was how Akira was initially found by his friend Masaru in the anime, when the latter wandered off and found him on an operating table connected to various machinery]].
* RealityWarper: The only one capable of stopping Tetsuo's EldritchAbomination form by teleporting him to another dimension, destroying Neo-Tokyo in the process.
* TheStoic[=/=]TheUnfettered: Willing to stop Tetsuo in the later half of the manga by whatever means necessary. Barely emotes.
* TheyWouldCutYouUp: [[spoiler:In the movie they ''did'' after he died. However, he fails to stay cut up.]]
* TrueCompanions: [[spoiler: As it turns out, all psychic children consider each other this. Including Akira]].
* WoobieDestroyerOfWorlds: [[spoiler:Akira was created as part of a secret government project to create psychic children that can be used as military/political weapons, but when he grew too powerful he was cryogenically sealed underground and forgotten until Tetsuo found him. Then after emerging into the outside world, the first thing Akira saw was an old friend, Takashi being brutally shot dead in front of him, causing Akira to single-handedly destroy Neo-Tokyo in a rage. For most of the manga he was sought by factions led by Lady Miyako and the Neo-Tokyo Empire, and used by Tetsuo to gather a massive cult following among Neo-Tokyo's survivors. Kid's got a ''really'' hard life]].

[[folder:Kiyoko, Takashi and Masaru]]
->Kiyoko is voiced by: Sachie Ito (JP), Melora Harte (EN, Streamline dub), Creator/SandyFox (EN, Animaze dub), [[Creator/IsabelMartinon Isabel Martiñón]] (LA, first dub), Creator/RossyAguirre (LA, second dub), Lola Oria (SP, first dub), Mayte Supervía (SP, second dub), Paula Ribó (SP, third dub)
->Takashi is voiced by: Tatsuhiko Nakamura (JP), Creator/BarbaraGoodson (EN, Streamline dub), Cody [=MacKenzie=] (EN, Animaze dub), Creator/VictorUgarte (LA, first dub), Kalimba Marichal (LA, second dub), Alberto Trifol (SP, first dub), Olga Supervía (SP, second dub), unknown (SP, third dub)
->Masaru is voiced by: Kazuhiro Kando (JP), Creator/BobBergen (EN, Streamline dub), Love Santini (LA, second dub), unknown (SP, first dub), Ana Romano (SP, second dub), José Antonio Torrabadella (SP, third dub)

* AfraidOfBlood: In the anime, the three are so terrified when Tetsuo accidentally cuts himself on a shard of glass [[spoiler:that it foils their attempt to assassinate him]].
* AnimalMotifs: Kiyoko is represented by a rabbit because she is physically weaker than her friends and relies on them to protect her. Takashi is represented by a bear because of his generally pacifistic nature, but he will reveal his claws if he has no other choice.
* ApologeticAttacker: [[spoiler:Takashi uses his PsychicPowers to pretty much ''blow up'' a girl named Mozu, but it's clear that he saw it as the only alternative and apologizes to her before ''and'' after doing so.]]
* AscendToAHigherPlaneOfExistence: [[spoiler: Possibly what happens to the Espers in the manga]].
* BerserkButton: Harming and/or threatening Kiyoko is this for the Espers.
* BigBrotherInstinct: Kiyoko is physically weaker and constantly bedridden, thus unable to defend herself. Takashi and Masaru, who are healthier by comparison, are very protective of her and are willing to shield Kiyoko from anything they perceive to be a threat.
* CreepyChild: All three can come across as this, due to their wizened appearance and their WiseBeyondTheirYears behavior.
* GildedCage: The Nursery serves as this for the Espers, possibly because [[HeKnowsTooMuch they know too much]] about what the government intends to do with their psychic powers, and to prevent information about the government's psychic project from being revealed.
* GirlishPigtails: Kiyoko has braids, actually. Although she is far from youthful.
* HandicappedBadass: Masaru. Fighting an angry psychic teenager who is wholly more powerful than he is despite not being able to walk takes a lot of balls.
* HarmfulToMinors: In both the manga and the animated film, Takashi watched a member of the resistance be viciously gunned down by riot police. You can guess what happens next...
** [[spoiler: It is revealed later on in the manga that before the original Tokyo's destruction, the Espers were subjected to a series of horrible experiments by the government in order for their psychic powers to develop and grow, so they can be used as weapons]].
* IllGirl: Kiyoko is bedridden and has weaker health than the others. Masaru has polio and is confined to a wheelchair.
* MassTeleportation: [[spoiler: During Akira's destruction of Neo-Tokyo, Kiyoko was able to amass an unusually large amount of energy to teleport a large group of people (including most of the main characters) to a safer place]].
* MeaningfulName: Kiyoko, when spelled with the kanji 聖子, means "holy child", which fits in with her psychic powers and ability to see the future.
* MindOverMatter: Takashi and Masaru's powers. Kiyoko is implied to have this [[spoiler: as she was able to levitate herself and carry Takashi's dead body (for a short time) while Akira destroys Neo-Tokyo]].
* MysticalWhiteHair: Kiyoko and Takashi.
* NiceJobBreakingItHero: Takashi being out on the road all by himself directly led to Tetsuo's motorcycle accident, which later led to Tetsuo's psychic powers emerging along with a series of events that ultimately resulted in Neo-Tokyo being utterly demolished. [[SarcasmMode Thanks a lot, Takashi]].
* NeverGrewUp: Implied to have been a result of the government's experiments and all the drugs they have to take. However, while they stayed children, their bodies aged prematurely, so they look unnaturally old.
* OhCrap: Takashi's reaction in the manga [[spoiler:when he meets Tetsuo again sometime after the motorcycle accident]].
* OlderThanTheyLook: Due to the drugs and the experiments, the Espers aged prematurely, so they look like they're between their late-40's and early-50's.
* ParentalAbandonment: [[spoiler: The Espers were possibly orphans and government wards, as there were no mentions of their parents]].
* PinkIsFeminine: In the anime, Kiyoko is seen wearing pink clothes. She even sleeps in a pink bed, surrounded by various toys and dolls.
* ProperLady: Kiyoko had shades of this in the anime [[spoiler: in the Espers' flashback before she became the physically ill girl who was constantly confined to her bed]].
* PsychicChildren: [[spoiler: They, including their Akira, were part of a secret government project that sought to develop psychic powers in children so they can be used as military/political weapons]].
* PsychicLink: All three are mentally connected to Akira. [[spoiler:When Takashi is shot in the head by Nezumi, the surviving Espers scream in pain as they felt their friend dying in front of them. When Akira is later shot by Ryu toward the end of the manga, both Masaru and Kiyoko sense his pain and teleport to his side]].
* SacrificialLion: [[spoiler:Takashi, who gets shot in the head by Nezumi (who was aiming for Akira.) And right when he had found Akira and was happily going to him! This completely causes an horrified Akira to fall in despair and fully release his powers, '''taking almost all of Neo Tokyo with him'''.]]
* SleepyHead: Kiyoko, due to being physically weaker and bedridden from the drugs and experiments. Using her psychic powers tend to tire her out for long periods of time.
* SparedByTheAdaptation: [[spoiler:Takashi, in the movie.]]
* StrappedToAnOperatingTable: [[spoiler: Masaru found his friend Akira like this in the anime during the Espers' flashback. Then later, all of the Espers were subjected to this to develop their budding psychic powers]].
* SuperpowerMeltdown: In the manga, Takashi's psychic powers get out of control without the steady supply of drugs he needs to suppress them. It's possible that any Esper can have this happen to them if they stop taking drugs.
* TeleportersAndTransporters: Kiyoko has the ability to teleport. [[spoiler: This saves the main characters from being killed during Akira's destruction of Neo-Tokyo in the manga]].
* TrueCompanions: Due to being psychics, the Espers have a deeper understanding of each other than anyone else. [[spoiler: It's what allowed them to endure horrible experiments at the hands of the Japanese government pre-AKIRA]].
* TwoGuysAndAGirl: But since they're children, their relationship is platonic.
* WaifProphet: All of them, but especially Kiyoko who is bedridden and constantly hooked up to life support.
* WiseBeyondTheirYears: All of them tend to know things most people don't, but especially Kiyoko, who is gifted with precognition and can see the future.

->Voiced by: Creator/YurikoFuchizaki (JP), Creator/BarbaraGoodson (EN, Streamline dub), [[Creator/MichelleRuff Georgette Rose]] (EN, Animaze dub), Carola Vázquez (LA, first dub), Aurora Ferrándiz (SP, first dub), Berta Cortés (SP, second dub), Creator/NuriaTrifol (SP, third dub)

* AwLookTheyReallyDoLoveEachOther: In the manga, even if Tetsuo is cruel towards her, they allow each other to sleep on their laps [[spoiler:and Tetsuo loses control over his power after Kaori dies.]]
* BreakTheCutie: More like [[spoiler: crush the cutie]] in the anime.
* CruelAndUnusualDeath: [[spoiler:In the anime. During Tetsuo's mutation he accidentally crushes her, ''and we see everything.'']]
* FanDisservice: She has at least a scene in both the anime and manga where she's naked, it involves her getting sexually assaulted by gang bikers and forced to be Tetsuo's sex slave.
* LivingEmotionalCrutch: In the manga, she is Tetsuo's closest confidante and the one he turns to when he needs to be consoled. When she [[spoiler:is shot to death in an attempted coup, Tetsuo's grief leads to his losing his grip on the power completely.]]
* LoveMartyr: Even if Tetsuo shouts some verbal insults at her and tries to force her into sex slavery, she stays loyal to him.
* MoralityChain: She's one of the few persons Tetsuo cares for. [[spoiler:When she dies in the manga, he went APESHIT.]]
* SexSlave: Tetsuo originally came across her when he had his flunkies going rounding up good-looking girls in his territory, so he could force them to participate in an orgy with him.
* ShrinkingViolet: Moreso in the anime, where she's really shy and doesn't talk to anyone besides Tetsuo.
* StockholmSyndrome: In the manga, Kaori comes to feel sympathy towards Tetsuo, despite the fact he forcibly recruited her and tried to turn her into a sex slave.
** AMatchMadeInStockholm: Compare it with Tetsuo's LimaSyndrome towards her.
* TokenGoodTeammate: To the Great Tokyo Empire.

[[folder:Lady Miyako]]
->Voiced by: Koichi Kitamura (JP), [[Creator/SteveKramer Drew Thomas]] (EN, Streamline dub), William Frederick (EN, Animaze dub), Alejandro Illescas (LA, first dub), Abel Rocha (LA, second dub)

* [[AFatherToHisMen A Mother To Her Followers]]: She deeply cares for her followers and anyone under her protection. [[spoiler:When Sakaki is mortally wounded by the Colonel's soldiers, Miyako senses her death and screams the girl's name. She grieves her loss for the rest of the manga]].
* BlindSeer: She possesses [[MySignificanceSenseIsTingling clairvoyance]], which is similar to Kiyoko's precognition, except it allows her to sense everything that happens around her in the present day and also compensates for her blindness.
* DemotedToExtra: In the film, she's just a religious zealot who only has three scenes before [[spoiler:being killed off]].
* DoesThisRemindYouOfAnything: While probably coincidental, she seems to play a very similar role to Mother Abigail in ''Literature/TheStand''.
** Then again, the book does seem to have a decent following in Japan. Creator/NaokiUrasawa is also a fan.
* GambitPileup: Engaged in one with the military. Basically she can't directly expose the truth about their experiments because it would cost her the cult she built around herself and they can't expose her as a fraud without publicly acknowledging their own misdeeds, all while they both try to undermine each other behind the scenes.
* GodGuise[=/=]ScamReligion: A somewhat more benevolent example than most. She uses the powers she got from the government's experiments to convince people she's a MessianicArchetype in order to gain followers to help her bring down the sadistic military industrial complex that ruined her life. She does seem to genuinely care about her followers, doing all she can to help people after the city is destroyed and even seems to believe some of her own hype, as she considers her powers and those of the other psychics to be a manifestation of some greater mystical force that the military simply blundered into discovering.
* HeroicSacrifice: [[spoiler: She goes to battle a mutated Tetsuo with a couple of her most powerful followers so Kiyoko and Masaru can be protected, despite Tetsuo being way more powerful than all of them combined]].
* LettingHerHairDown: [[spoiler: Does this in the last volume as she prepares to battle a mutated Tetsuo]].
* MentorArchetype: Assists Kei in [[spoiler:honing her skills as a medium]].
* ParentalFavoritism: It is implied that although she loves all her followers, Sakaki has a special place in her heart. [[spoiler: When Sakaki is killed, Miyako spends the rest of the manga grieving her death]].
* ParentalSubstitute: Is possibly this to Mozu, Miki, and Sakaki, who were likely orphans taken in by her church.
* ProphetEyes: Has milky, clouded eyes to visually represent her blindness. Also possesses clairvoyance, which allows her to sense present-day events as they happen around her.
* PsychicLink: [[spoiler: Turns out she had one with the Espers. She was able to sense Takashi's death after he was shot by Nezu, and later when Akira is shot by Ryu in the manga, she and the surviving Espers can sense it]].
* TeamMom
* TechnicalPacifist: Miyako and her empowered monks try to repel an invasion of the temple by Empire soldiers non-lethally.
* WomanInWhite: Like all of her followers, she is dressed entirely in white.

[[folder:Sakaki, Mozu and Miki]]
* AloofDarkHairedGirl: Miki looks older than the other three girls and acts very aloof.
* FatGirl: Mozu is noticeably plumper than the other girls. [[LightningBruiser It doesn't exactly stop her.]]
* KillItWithFire: Mozu tries to take out Takashi with this. It didn't work as he turned out to be more powerful than her.
* LeanAndMean: Miki is noticeably thinner than the other girls, but she's not really mean, as she has a close friendships with Mozu and Sakaki. She's just ruthless and very dedicated to bringing Akira to Lady Miyako.
* ParentalSubstitute: All three girls possibly see Lady Miyako as this, especially Sakaki. [[spoiler: When Sakaki is fatally shot by Colonel Shikishima's men, she imagines Miyako welcoming her with open arms before she dies.]]
* RoaringRampageOfRevenge: [[spoiler:Sakaki]] goes absolutely apeshit when she sees [[spoiler:Takashi]] a while after [[spoiler:he kills Mozu in front of her.]]
-->'[[spoiler:'''Sakaki''']]: "YOU KILLED [[spoiler: MOZU]]! I'LL KILL YOU!"
* TrueCompanions: They see each other as such. [[spoiler:Miki calls out to Sakaki and Mozu when she's shot to death to cover their escape, and later Sakaki is '''horrified''' when Mozu dies.]]
* UndyingLoyalty: The three girls are totally devoted to their leaderess, Miyako, [[IOweYouMyLife who took them into her group and gave them something to live for]].

* AdaptedOut: Sadly, she does not appear at all in the movie.
* BrawnHilda: However, she's not very ugly.
* MamaBear: Never EVER touch anyone in her protectorate. Like Kei. [[spoiler:Or the psychic children.]]
* VasquezAlwaysDies: [[spoiler: Averted. She's wounded and feverish for a large chunk of the story, but ultimately survives.]]

* DemotedToExtra: In TheMovie, we only see him in the very beginning.
* EnemyMine: He and Kaneda form an alliance to fight against Tetsuo's "empire."
* HeelFaceTurn: In the manga, he helps fight against Tetsuo.
* MonsterClown: Averted in the manga where he becomes pretty friendly, as well as a valuable ally in the battle against Tetsuo towards the end.
* ScaryBlackMan: Sort of. His face is pretty Asian-looking, but he has very dark skin.

->Voiced by: Hiroshi Otake (JP), Tony Mozdy (EN, Streamline dub), Ray Michaels (EN, Animaze dub), Victor Mares (LA, second dub)

* AnimalMotifs: The rat. His overbite and facial features are shaped similar to a rat's, and he displays [[YouDirtyRat treacherous behavior that a rat in fiction would display]]. Lady Miyako explicitly calls him a rat, but also refers to him as a "mouse" at one point.
* {{Irony}}: [[spoiler:In the movie, he fatally shoots Ryu, but Ryu outlives him by about a minute thanks to a sudden heart attack.]]
* MeaningfulName: His name means "rat" in Japanese.
* TheMole: In the movie, Nezu is the anti-government group's spy in the Executive Council, but [[DoubleAgent he's perfectly willing to stab both sides in the back.]]
** DoubleReverseQuadrupleAgent: In the manga, he's allied to Lady Miyako and her aides in addition to his allegiances above, but the truth is he's playing all sides in order to grab power for himself, so when Akira is thrown into the mix he tries to kidnap the kid so he can use him for political leverage.
* UnwittingInstigatorOfDoom: In the manga. [[spoiler: He tries to shoot and kill Akira but winds up accidentally shooting Takashi in the head, which causes Akira to have a ''massive'' FreakOut and destroy Neo Tokyo, reducing it to a post-apocalyptic wasteland ruled by two different factions.]]

[[folder:Kaisuke / "Kai"]]
->Voiced by: Creator/TakeshiKusao (JP), Creator/BobBergen (EN, Streamline dub), Anthony Pulcini (EN, Animaze dub), Creator/GabrielRamos (LA, first dub), Creator/RicardoMendoza (LA, second dub), José Luis Mediavilla (SP, first dub), Álex de Porrata (SP, second dub), Pablo Sevilla (SP, third dub)

* ActionSurvivor: He manages to survive the entire manga, ''and'' in the movie, is one of the four main survivors. (The other three being Kaneda, Kei, and the Colonel)
* {{Adorkable}}: Even though he's part of a biker gang, he definitely comes across as this.
* SharpDressedMan: He's more cleanly dressed than his fellow Capsule gangsters, including wearing a tie with his outfit.

->Voiced by: Masaaki Ōkura (JP), Tony Mozdy (EN, Streamline dub), Michael Lindsay (EN, Animaze dub), Creator/LuisDanielRamirez (LA, first dub), Emmanuel Rivas (LA, second dub), Ángel de Gracia (SP, first dub), Marc Zanni (SP, second dub), Aleix Estadella (SP, third dub)

* BackForTheFinale: [[spoiler: His spirit appears driving alongside Kaneda as he rides off in the final chapter of the manga.]]
* BigGuy: The tallest and seemingly most muscular member of the Capsules, and [[BloodKnight usually the most eager to throw down]].
* TheLancer: Briefly. He's Kaneda's right hand man im the Capsule gang, and much more HotBlooded and aggressive than his leader. [[spoiler: His death, of course, means the end of this.]]
* NothingIsScarier: In the movie, [[spoiler:his death was never shown onscreen, and Kai did not explain how he died either...]]
* PipePain: Weapon of choice.
* VikingFuneral: Yamagata gets the bosozoku version of this in the animé, with Kaneda deliberately crashing his bike.
--> '''Kaneda:''' I'm gonna send Yamagata his wheels...

* DrowningMySorrows: In the manga, he does this to cope with the deaths of his friends.
* LibationForTheDead: Ryu pours out his flask for a fallen comrade at the scene of his death.
* LovableCoward: In the manga, he jokes that he'll be right behind you running into danger and just ahead of you running ''from'' it. This is probably just self deprecation, because he shows plenty of courage.
* WouldHurtAChild: [[spoiler: In the final book of the manga, he shoots Akira to prevent an impending psychic explosion that would have been powerful enough to destroy the world. Though it was clear that he was ''very'' reluctant in doing the act]].