The ''Messing with Sasquatch'' commercials for Jack Links beef jerky has the Sasquatch going ballistic and inflicting harm upon people who decide to provoke him for cheap laughs.
An insurance commercial shows a bunch of rabbits laughing themselves sick at a rattlesnake with a pink and white baby-rattle in place of a normal one. Did the writers not know that it's the other end of a rattlesnake that's venomous?
A couple Stacker 2 commercials had a man make fun of Kane, a sadistic monster heel from the WWE. Ends about as well as you'd expect...
A Spike TV commercial has a pair of convention-goers mock Boba Fett for his unusual name and appearance. It ends badly for them.