A tongue-in-cheek instance was used in commercials for the "Geek Squad" technical support service broadcast in late 2004.
This Snickers commercial had an interesting subversion: A Viking, after learning a store had no Snickers, initially does a Big No straight and while doing so, throws a garbage can at a car to get his point across. After learning that they had dark chocolate Snickers, however, he does the exact same thing as before... except with a "Big Yaaaaaaaay"!
Parodied in an advertisement for the Samsung Epic 4G. An officer of a civil-war army receives a letter, and utters a Big No upon reading it. The parody is that the note is then shown to actually say "NOOOOOOOOOOOOOOOOO" for an entire page.
An advertisement at a movie theater for related discounts has a Roman-looking soldier approach his general in a tent, handing him a letter. The general opens it and immediately yells "NOOOOOOOO...!" Cut to a view of the letter, which is just the word "Nooooooooooooooo" spread across the letter in cursive.
In the 1995 Cap'n Crunch Berries commercial, a teenager does one when he is told that the store is out of Crunch Berries.
A fat man inside a teenager's stomach screams "NOOOOOOOO! NOOOOO!" when his fridge is empty in the 1997 Taco Bell commercial.
JCPenney's newest advertisement which can be seen here on YouTube shows numerous shoppers yelling "NOOOOOOOO!!!!" upon seeing sale prices in other stores; the advertisements announce JCPenney's discontinuation of accepting coupons after February 1, 2012.
A commercial for Subway's breakfast offerings has a fast food restaurant manager doing this when looking up at the sky as a big banner-like announcement pronouncing Subway's 200-calorie breakfasts is shown. As a contrast, everyone else in the commercial says, "Yes!"