Dizzy Cordova of 100 Bullets, with her true first name being Isabel. Also most of the rest of the Minutemen, with Meaningful Names or Punny Names like Jack Daw, Victor Ray, Cole Burns, and Lono, named after a Hawaiian god.
Tintin means something along the lines of "nothing at all." It's apparently his last name.
"Tintin" sounds like a lot of French nicknames which take a syllable from a name and reduplicate it, such as Fifi (for Sophie, Yvonne, Josephine), Popaul (Paul) (Bébel (Jean-Paul Belmondo) once played the titular hero of the film Dr. Popaul), Didi and Gogo (Vladimir and Estragon). Tintin could be derived from Célestin, Constatin or Martin, good Catholic names for the hero of a series created for a Catholic newspaper. The first serial hero Hergé created was the boy-scout Totor.
In French: Professeur Tournesol (Sunflower) translated as Calculus in English. Capitaine Haddock (like the fish), Bianca Castafiore, which in Italian means White Chasteflower, in Secret de la Licorne (The Secret of the Unicorn) the Loiseau brothers (Meaning Thebird brothers (just "Bird brothers" in the translation). Lampshaded when they are identified by a man they shot pointing at birds). In Vol 714 pour Sydney (Flight 714) Laszlo Carreidas translates as Laszlo Four Aces (as in a poker game). Also in Flight 714, first appearing in Coke en Stock (The Red Sea Sharks), is the pilot Szut. "Zut" is a very mild French expletive. Lampshaded when Captain Haddock thinks the man is cursing when asked his name. There are quite a few more, making Hergé a master of this trope.
In Hopeless Savages, the main character is called Skank Zero Hopeless-Savage. Her siblings' names are Rat Bastard, Arsenal Fierce and Twitch Strummer, all Hopeless-Savages. The reason being that their parents are punk musicians Dirk Hopeless (formerly his stage name, later legally changed) and Nikki Savage (her birth name).
Scott Pilgrim: Knives Chau. "Who names their kids Knives?!" Most of the Scott Pilgrim characters also qualify, including Scott Pilgrim, Ramona Flowers, Gideon Gordon Graves, and Envy Adams, though that's not her real first name (it's derived from Natalie V).
The writers of comics, considering that Marv Wolfman exists.
The X-Men universe is full of them. Let's start with Noriko Ashida, Alison Blaire, Raven Darkholme, Cessily Kincaid, Remy LeBeau, Jubilation Lee, Katherine Pryde, Cain Marko, John Proudstar, Quentin Quire, Julio Esteban Richter, and Monet Yvette Clarisse Maria Therese St. Croix.
Slade Deathstroke the Terminator. Deathstroke. His actual name is Slade Wilson. Deathstroke the Terminator is his nom de guerre. InTeen Titans, he just went by "Slade".
Power Man was born Carl Lucas, but promptly changed his name to Luke Cage. These days he goes by Luke Cage because frankly that's just as bad-ass as "Power Man." (Nicolas Coppola agreed that "Cage" was way better.)
Pick a male Wolfrider from ElfQuest; two out of three have names like Bearclaw, Strongbow, One Eye, Mantricker, Redlance, and so on.
Joseph Dredd. Justified in-universe: Dredd is a clone of Fargo, the founder of the Judges, and the name was specifically chosen to inspire... well, dread. Other examples include Sidney D'Eath AKA Judge Death, Judge Kraken Jack Point.
Lampshaded with the latter: "What's the point?" "Comes right after the Jack."