Not to mention put Isaac in his place with the apple story.
Which rolled over into a Crowning Moment of Funny the next time he ran into Brent Spiner. The first words out of his voice box, "Where's my money."
Maintaining his sense of humor, his mental sharpness, even just his sanity when trapped in an immobile body for years and years has to be a CMOA. As GQ's The Rules once said "It should be Stephen Hawking's and Lou Gehrig's Disease."
When he was diagnosed with Lou Gehrig's disease the prognosis was that he had 2 years to live... that was in 1963. Death is now Stephen Hawking's bitch.