- Isaac's editorial in "The Six Southern Gentlemen of Tennessee":
Jeremy: Isaac, no fooling; play of the year.
- Jeremy's speech to Natalie in "Shoe Money Tonight":
Jeremy: I want you to trust me right now. I want you to say to yourself, yes, I've dated a string of jerks in my life, they were stupid, they were mean to me, but maybe this one's different. Maybe I should take a chance and not adopt the break-up-with-him-before-he-breaks-my-heart strategy. I want you to remember that when I started liking you, I didn't stop liking tennis. And I want you to know that I don't think there's a woman in the world that you need to be threatened by, no matter how glamorous you think she is. But mostly, I want you to trust me, just once, when I tell you that you have three sevens, and I have a straight.
- Sam Donovan's dismissal of the meddlesome executives near the end of the episode "Cliff Gardner":
Sam: One last thing. The first and last decision-making authority on this show will rest with Isaac Jaffee until Isaac Jaffee says otherwise, and if you disrespect him in my presence again, I will rededicate the rest of my life to ruining the rest of yours. And if you think I'm just mouthing at you, you should ask around about me. I have absolutely no conscience about these things.
J.J.: Sam, why did you bring us out here?
Sam: Because there's the exit. That's it. The meeting's over.
- Casey casually brought up Rosa Parks during an argument with Isaac Jaffee, naively comparing his struggle with network executives to her struggles in the civil rights movement. Jaffee ignores the comment, and they ultimately come to a peaceful compromise. However, as Casey is leaving Jaffee's office, we're treated to this legendary (and justified) gentle-but-firm verbal smack-down by Jaffee:
Isaac: Casey, I like you, so I'll let what you said earlier go. But remember this, because I'm only going to say this one: no college-educated white boy ever got on my good side comparing himself to Rosa Parks.