- The Silver Streak plowing through the wall and the souvenir shop in glorious slo-mo and finally coming to rest in the concourse is a scene rarely matched but constantly imitated (but successfully parodied in Airplane!).
- The entire last twenty minutes of the film are a chase between the train and two helicopters, then later a Runaway Train... and forty years later, it's still a nerve-wracker.
- George's mounting frustrations granting him a brief Took a Level in Badass, as the Too Dumb to Live sheriff pulls a gun on him and George just snatches it right out of his hand.
"You stupid, ignorant son of a bitch dumb bastard! Jesus Christ, I've met some dumb bastards in my time, but you outdo them all! GET OVER THERE!"
- Henry Mancini's score is not only romantic and soaringly beautiful, it's also throbbing with a locomotive rhythm that fits the film like a glove.