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Laurie finally grows a pair and decides to take on Michael head on. The whole fight was one-sided... with Michael on the defensive; He gets an axe and a spear slammed into his chest, a stick thrown at his head, gets stabbed several times, is knocked off a balcony and gets kneed in the groin. You could clearly see that he was both surprised and shocked by Laurie's ferocity.
It's also why the fans don't accept Resurrection as being canon, since letting Laurie finally kill Michael in this film is a pretty awesome ending, and well deserved.
Nurse Marion manages to hold off Michael pretty well with a poker, but he still managed to slice her neck open when she tried to call for help.
When Michael attacks John and Molly, John tries to hold Michael off by pulling a few good punches. When Michael stabs John in the leg, Molly grabs a rock and bashes it upside Michael's head so they can get away.