- Sam buying back Cheers in "Cry Harder".
Sam: Right. I, uh, OK I got eighty-five cents here.
Jim Montgomery: ...I'll take it.
Sam: Hey guys! I low-balled him!
- In "Coach's Daughter," when Lisa (Coach's... y'know) tells off her fiance, a Jerk Ass who was only marrying her so she (his boss) would give him a new sales territory.
Lisa: Roy, I don't want to marry you. I decided I want a man as good as my father.
Roy: Wait, hold on here. What about Pennsylvania?
Lisa: Roy, you don't get Pennsylvania, and you don't get me. You just get more and more obnoxious.
- Diane Chambers, of all people, stuns all silent with a Crowning Moment Of Awesome, when she saves the day bowling against Gary's Olde Towne Tavern—defending the honor of her sorority in the process. And while we're at it, she tops it all off with a sweet moment of Sophisticated as Hell:
(BIG cheer from the rest of the gang!)
- Rebecca in her first appearance laid down the law for Sam when giving him a second chance.
- The Cheers gang finally winning the feud with Gary in Bar Wars VII during the final season.
- And the triumphant return of Harry the Hat, still on the top of his game after a ten-year absence. Cheers wins the feud because Harry tricks Gary into having his bar demolished.
- Sam, in the first season episode "The Boys in the Bar", when the regulars are trying to pressure him into ejecting two suspected homosexuals by threatening to find another bar.
Sam: Hey, listen, those guys are staying. Anyone else wants to leave, that's fine.
Norm: Okay, Sam, you know what kind of bar this could turn into?
Sam: It's not going to turn into the kind of bar that I have to throw people out of.
- Coach, of all people, helping Harry with a Kansas City Shuffle to win all of Coach's poker winnings back from another con man. This made Harry the Hat a likeable Ensemble Darkhorse, instead of the seedy con man he could have been.
- Cliff has read that his medication can cause male breast enlargement:
Cliff: I see you all looking at my chestal area; stop it! I don't have breasts!
Rebecca: Don't let them get to you, Cliff. I took that medication and the risk of side effects is very overrated.
Cliff: Oh, yeah, Rebecca? How long ago did you take it?
Rebecca: About twenty years ago; back when I was a little boy.
- In the episode "Sam's Women," Sam thinks Diane thinks that the only women Sam can get are all stupid. Diane asserts that an intelligent woman would never fall for his lines. They argue about it (and insult each other), and finally apologize. Then they have this conversation:
Sam: Well I'll be darned.
Sam: Nothing, I just... noticed something.
Sam: Well I guess I've never, uh, never looked into your eyes.
Diane: Something wrong with them?
Sam: No, I, ah... I just don't think I've seen eyes that color before. As a matter of fact, I don't think I've ever seen that color before. [Shakes head] Yes I have, yes I have...
Sam: I was, ah, I was on a ski weekend, up at Stowe. I was coming in late one day, last person off the slope. The sun had just gone down... And the sky became this incredible color. I, I usually don't notice things like that. I found myself kind of walking around in the cold, hoping it wouldn't change. Wishing that I had somebody there to share it with. Afterwards I tried to convince myself that I'd imagined that color, that I hadn't really seen it, that... nothing on this earth could be that beautiful. Now I see I was wrong.
[Diane stares at him silently, near tears]
Sam: Wouldn't work, huh?
Sam: An intelligent woman would see right through that.
Diane: (Sadly) Oh— (covering loudly) OH...! In a minute!
- Made funnier by Diane turning, grabbing one of the drinks on her tray and gulping it down.
- Diane gets in a vicious one during their breakup at the end of Season 2.
Diane: Do you know what the difference between you and a fat, braying ass is?
Diane: The fat, braying ass would. (oh, snap!)
- Frasier's speech to Sam and Diane in the ending sequence of "Triangle":
Sam: You are so—!
Diane: This is NOT—!
- It's so awesome, the Studio Audience responds with thunderous applause!
- This was to be Kelsey Grammer's exit after fulfilling his 8 episode contract, but the producers decided Frasier Crane was too good of a character to throw away, and thus, 19 more years of Frasier Crane ensued in one form or another.
- The final sequence of "Chambers vs. Malone". After Sam proposes to Diane in court (It Makes Sense in Context...), Diane apologizes for putting him through the whole ordeal—and then promises not to hold him to the proposal. She then begins to leave—but...
Sam: Where are you going...? (Diane stops; turns to him as he rises) Y'know, you're not gonna get off that easy—y'know, you're gonna pay for what you put me through.
Diane: ...What do you mean...?
Sam: I proposed to you...you said "yes". Now they can stop me from killing you...but they can't stop me from marrying you.
(Pause. Diane stares at him. Sam smiles, beckoning with his finger.)
- Diane's moment in Season 4's "Cliffie's Big Score", where she walks into the bar in a glamorous and sexy evening dress, to the delight of all the guys in the bar. Diane girlishly revels in the admiration—understandably; she's the "popular gal" for the night!
Sam: (Straightening up as she heads over) Good heavens. Whoa!
Woody: Miss Chambers, you look beautiful!
Diane: Oh, thank you, Woody!
Sam: (Leaning back again; admiringly) Doesn't she?