->They are gifted, they are cursed.\\
Trained by a company to battle a resistance.\\
They have the power to save, and the power to kill.

''E's Otherwise'' (エス・アザーワイズ) focuses on Kai Kudou, an "Esper", who is recruited by an organization called Ashurum to become a soldier to purportedly save other psychics from regular humans. After a mission in Gald goes wrong, Kai finds himself living with a man named Yuuki and his adopted sister Asuka. As he learns more about Ashurum, Kai finds himself wondering what their true goals are, and worrying about his ill sister, who is under Ashurum's care.

!!Provides examples of

* AllLovingHero: Kai, who's convinced humans and Espers can get along despite all the AllOfTheOtherReindeer vibes and doing his best to achieve this. [[spoiler: Not to mention he, upon meeting the BigBad, asked him to stop rather than attacking.]] At least we know where his mindset lies on the SlidingScaleOfIdealismVersusCynicism.
* AllOfTheOtherReindeer: The Espers get this badly enough to make moving to Ashurum pretty much the only viable option, unless they manage to hide their powers from everyone. [[DoesThisRemindYouOfAnything Hmm...]]
* AttractiveBentGender: Kai, who wasn't really delighted to find out his female disguise had caused some rather... intense (bordering on StalkerWithACrush) feelings in someone who [[LoveAtFirstSight just happened to see him momentarily]].
* BadassGrandpa: Erimiya, who seems like a harmless old geezer at first glance. [[spoiler: Then he takes down Shinlu, who was going through his underlings effortlessly, via MindRape.]]
* BloodKnight: Kyou, who seems to get most of his kicks out of coming back to battle Kai time after time... [[spoiler: and tends to have undergone certain... modifications after every return.]]
* BrownNote: Dzhyma's little gadget. Harmless to ordinary humans, causes extreme pain and, with enough power, death to Espers. He made it ForScience
* BullyingADragon: Considering the Espers' powers the hostility against them is basically this. Further played straight by citizens of Gald during Ashurum's invasion, whose policy seems to be to antagonize everyone in Ashurum's clothing they come across, even the ones who are unarmed or are clearly clearly ''caring for one of them''. This comes back to bite them in the ass since Kai might've been nice enough to not retaliate, but [[RoaringRampageOfRevenge Shenlong, on the other hand]]...
* ConspicuousCG: Cityscape in the OP.
* CreepyCrossdresser: Shelly, who confuses things further by being rather... ''attached'' to Shinlu, making it look like [[HoYay Les Yay]] for the unaware. Made worse by the fact they don't really state it outright until the finale. UnsettlingGenderReveal followed.
* TheEmpath: Asuka, who is apparently able to sense emotions by touching people, and various intense emotions from great distances. Maria might have some qualities from this too.
* FriendToAllLivingThings: Asuka again.
* HopelessSuitor: Dzhyma was smitten with Asuka [[LoveAtFirstSight at first glance]]. Unfortunately for him, Asuka only has eyes for Kai. Doesn't stop him from declaring them rivals in love, though.
* IllGirl: Hikaru, Kai's beloved little sister and his reason for coming to Ashurum in the first place.
* TheIngenue: Asuka fits pretty well, except for the whole "immune to sexual innuendo" thing. (See PantyShot below.)
* {{Jerkass}}: Shenlong. So very much.
* JerkWithAHeartOfGold: Yuuki, who, to be honest, is basically a money-hoarding jackass who works Kai like a slavedriver, doesn't particularly seem to care about putting him into seriously dangerous positions and [[ArsonMurderAndJaywalking forces him to dress like a woman]]. [[AttractiveBentGender Twice.]] Also takes care of orphaned children, [[spoiler: donating most of the money he so loves to hoard to them,]] raised Asuka pretty much by himself and does come to care for Kai's wellbeing too. Even if he won't really admit it.
* LethalChef: Asuka, to the extent Yuuki ''couldn't speak for an entire day'' after tasting her cooking. She's been given a permanent ban from the kitchen, making this... [[StayInTheKitchen Stay Out of the Kitchen?]]
* [[BigBrotherInstinct Little Brother Complex]]: Shenlong, who ''does'' want to make Shinlu happy, but fails to actually listen to what she herself wants, gets rather... touchy whenever something seems to be threatening Shinlu... or taking her away from him. He pretty much crosses into KnightTemplarBigBrother territory when [[spoiler: going batshit insane upon finding Shinlu down for the count in Gald and subsequently wrecking a good portion of the city in his showdown with Kai]]. Then again, [[spoiler: his love for her does eventually [[EnemyMine put his hatred against Kai aside and cooperate with him]].]]
* ManipulativeBastard: [[spoiler: Mr. Eiji.]] Seems nice enough and [[spoiler: his interactions with Hikaru are definite PetTheDog material]]. ...Until you realize it was all probably a well calculated ploy to [[spoiler: get Hikaru to forget about Kai and make sure she'd cooperate in his attempts to bring about TheEndOfTheWorldAsWeKnowIt]].
* MegaCorp: 12 of them, to be exact. They decide pretty much everything.
* MundaneUtility: Kai's Esper powers and military training are, for most of the first part of the series, used for things like retrieving lost pets, stealing comic book thieves, getting ingredients for ramen and [[RunningGag dressing like a woman.]]
* OpeningNarration: Asuka's "My life with Kai and Yuuki" story.
* PantyShot: Just one ([[TheUnreveal and the audience never sees it]]) but it manages to double both as a SugarWiki/{{Funny Moment|s}} and the indication Asuka is neither the InnocentFanserviceGirl nor in need of the TheTalk. Remember, Yuuki, [[SkirtsAndLadders never make a girl with a short skirt climb a ladder]] before her {{Love Interest|s}}...
* PromotionToParent: Kai's and Hikaru's parents are nowhere to be seen so he became her caretaker. Yuuki is this for a whole bunch of kids and basically Asuka as well, despite being more fitting to be her brother age-wise.
* SacrificialLamb: Poor Ruri...
* SpeaksFluentAnimal: Asuka, of the "speaks human to the animals who make animal sounds in return and understanding is achieved" variety. Apparently, somewhat linked to her being...
* ThouShaltNotKill: Kai, who will go for non-lethal incapacitations without fail. Even against MechaMooks. (Though the Mecha Mook in question ''was'' once human, but...)
* WeHelpTheHelpless: While living with Yuuki and Asuka.