Tex from Red vs. Blue, more than capable of easily handling entire outposts on her own. The only character noted to be tougher than her in combat was the superhuman Meta, and only because he had a bunch of abilities he stole from other people. Without them, he had to gang up on her 2 against 1 to beat her.
Any female Freelancer qualifies as this, to one degree or another. Say what you want about South, but season 9 shows she's quite the badass. And Carolina wiped the floor with an even larger number of troops, single-handedly. CT initially seems to be an exception to this, but as is discovered in season 10, she's actually able to hold her own fairly well against both Tex and Carolina until she was killed, of course.
RWBY has tons of examples. The protagonists alone fill all of the major archetypes: Ruby is the rough-and-ready hack-and-slash type, Weiss is more of an elegant and precise Magic Knight, Blake is an acrobatic rogue-ish/ninja type, and Yang is a tough, aggressive brawler with a pair of shotgun gauntlets.
Since the Whateley Universe is a superhero world, it's not surprising that every female main character is this. Except Summoner, who's a White Mage and Squishy Wizard right now. Plus several auxiliary characters like the headmistress (who is Lady Astarte in her spare time) and a bunch of the female teachers.