* AlternateCharacterInterpretation: Is Victoria telling the truth about beating Bobby Fischer at a private chess match at 13, but being kept away from public competition just because of her gender? Or is she making it all up to boost her own legend and strengthen her power on her followers? Considering that Fischer did not play a competitive game between 1972 and 1992, and then immediately became a fugitive, makes her claimed match very suspect.
%%* BrokenBase: [[spoiler:Issue 10, or the ending]].
%%Do NOT add back any Complete Monster examples per the Cleanup Thread's decision.
* CriticalResearchFailure: Some of the Daughters of the Amazon burn off their left breast to emulate mythological Amazons. Mythological Amazons supposedly removed their right breast to improve their archery. Removing the left breast makes no sense; for it to have any effect the archer would have to torso twist and hold the string away from the body with weaker muscles. The Daughters would have quickly figured this out since they are repeatedly seen using bows. Hero is depicted trying to make this work but it's painfully awkward to look at.
* EpilepticTrees: ''Encouraged,'' WordOfGod has stated that the "truth" behind the {{gendercide}} is stated somewhere within the series, [[FanDislikedExplanation but has not confirmed which of the (many) theories is the correct one]].
* TearJerker: At least one per volume.
** The biggest is the numerous shots of the immediate aftermath of the plague.
** 355's flashback [[spoiler:where she learns that her family is dead]] isn't easy to read.
** [[spoiler: Or when she's killed ''right'' after she and Yorick admit their love for each other]].
** [[spoiler: Or 87-year-old Yorick's incredible bitterness after spending his whole life without her.]]
** For anybody that has a pet they love, [[spoiler: the scene where Yorick takes a dying Ampersand to his burial spot - close to what appears to be 355's - could be tough to read]].
-->'''[[spoiler:Yorick]]:''' [[spoiler:They said it wouldn't hurt, Amp. I...I didn't want you to hurt anymore. They promised it would be quick. (''after feeding Ampersand a poisoned grape'') Why the fuck did I do that?]]
* TheWoobie: Yorick himself, at times. Also definitely Hero considering a lot of her past.