** Dempsey plays a successful [[spoiler: (and two-timing)]] [[Series/GreysAnatomy surgeon]].
** When Topher Grace questions the ringtone of his girlfriend, thinking it sounds techno, she says it's more retro, very [[Series/That70sShow '70s]].
** Lautner's Willy: "I'm not really comfortable taking my shirt off in public." Possibly the funniest line in the movie for Twilight fans. (Or anti-fans, we're really not picky.)
** The limo driver asks Julia Roberts if she'd ever shopped on Rodeo Drive. [[Film/PrettyWoman The answer?]] "Big mistake. Huge."
** A flight attendant on the airplane Julia Roberts and Bradley Cooper are flying on announces that the weather in Los Angeles has cleared up after "three days of rain" (the title of a play that Cooper and Roberts had starred in together on Broadway).
* HilariousInHindsight: Sean coming out as he prepares for free agency is oddly similar to basketball player Jason Collins.