* CrackPairing: A lot of fan art pairs [[LesYay Rose and Shade]] or [[NoYay Walter and Dr. Glasner]], both of which are homosexual relationships that have absolutely ZERO hints in the comics. Even the CREATOR of the comic drew a Rose x Shade piece.
* CrowningMomentOfFunny: [[http://tryinghuman.com/?id=479 This strip]] is one of many.
** [[http://tryinghuman.com/?id=522 This one]] starts with a [[CrowningMomentOfFunny CMOF]] and ends with a TearJerker.
* JerkassWoobie: [=EBE1=] is an asshole... [[EarthShatteringKaboom who saw his planet and nearly his entire species die around him.]]
* HoYay: Blatant with obviously gay couple Longus and Don.
* {{Moe}}: Admit it, Hue is adorable.
* MoralEventHorizon: Glasner crossed it [[http://tryinghuman.com/?id=3 in one of his first appearances]], and was willing to send Phyllis in to where [=EBE1=] was as a SacrificialLamb and locked the door. Glasner, in many opinions, has zero redeeming qualities.
** Glasner just keeps JumpingOffTheSlipperySlope even more as the series progresses. He keeps Phillis [[FateWorseThanDeath ALIVE IN A JAR]] in his office and pretty much lies to Roger about why he was chosen as part of Majestic 12. He also knows about Rose, and apparently plans something for her, which upsets Jar!Phillis enough that she uses the printer to communicate "LEAVE ROSE ALONE!" to which Glasner simply states "You stay out of this."
* NightmareFuel:
** For parents, Phillis getting shot trying to escape the base while carrying what most assume to be her baby. Dying, while holding your child, not knowing whether it too was going to be killed, or what was even going to happen to it? Terrifying, for anyone who is parent.
** Eight [[spoiler: being attacked by Magnus while holding her infant son.]]
* NotQuiteHuman: Even with the circuits, none of the aliens appear to be human at all except at first glance, which is apparently all that is needed to 'mingle' on Earth. Longus is good enough at it to DATE humans, although Don knows there is something weird about him. [[spoiler: Recently, Longus has revealed himself to Don. We have yet to see Don's reaction.]]
* StrangledByTheRedString: Rose seems genuinely disturbed and haunted by Hue's harassment, so she ... asks him to accompany her for a walk on the beach? This might actually be justified [[spoiler: apparently Rose and Hue have known each other for a real long time, even if they don't remember.]]
* UncannyValley: Besides the fact that they are kidnapping people for experiments, this is why Rose is afraid of Shade and Tone.