* EsotericHappyEnding: Johnny fulfills his wish; But... because they're only changing memories, not the past, [[spoiler: the real Johnny dies never knowing what his wife was trying to tell him, and the real River dies knowing Johnny never understood/remembered what she kept trying to hint at. Well, assuming ''any'' of it was ever real to begin with]].
* FridgeBrilliance: Why didn't River just tell John about [[spoiler: their first meeting, without going through the whole rabbit ordeal]]? At first it seems that it's only due to her [[spoiler: Asperger's]], but revisiting the first part of the story, it becomes apparent that she wanted, in her own way, to bridge the gap between them by [[spoiler: reminding him of (arguably) the only time when they truly connected]], and that wouldn't work unless he remembered on his own.
** FridgeLogic: On the other hand, [[spoiler: Didn't River in all those years, ever learned of Johnny's past and the reason he never remembered?]]
*** Johnny [[spoiler:couldn't remember his past, and his mother either intentionally hides it or has snapped and thinks Johnny is Joey. In light of this, there's no way for River to have ever learned about it.]]
** When you realize that River made the [[spoiler:rabbits to try and remind Johnny of their first meeting. And that when the white rabbits didn't work, she tried a yellow one, because the moon is yellow. And that when the yellow one didn't work, she managed to make one with a yellow belly (for the moon) and blue head and feet (for the sky and stars). To add an extra layer to it... Her wedding dress was yellow and blue.]]
* FridgeHorror: During TheStinger, it's implied that [[spoiler: Neil might be dying.]] And once you think about it, you come to understand why he's constantly acting immature, doing stupid things, being mean, jerkish and funny: He's trying to make the most out of life before he dies...
** [[spoiler: It's implied that all of the game's events in fact take place in Neil's head, quite possibly while he is in a similar state to John. Consider the Deja Vu of the squirrels running along the same path twice, almost like a glitch in the matrix.]]
** The first theory is further hinted at the very beginning of the game, in an optional scene you could miss entirely if you played as [[spoiler: Eva]]: the mock RPG fight against the squirrel. If you check [[spoiler: Neil]]'s health bar, you'll see it's not full. If you play with [[spoiler: Eva]], the bar will be full.
** To support the theory that [[spoiler: Neil is dying]], at the carnival when they meet the fortune-teller, [[spoiler: Neil refuses to see his future.]] "Good or bad, I'd be s****ed either way."
* GeniusBonus: A few small ones.
** The agency is called Sigmund Corp. As in Sigmund Freud, the famous psychologist.
** [[spoiler:Izzy describes Johnny as "neurotypical," which is not a word that's thrown around much outside of people who know a few things about the ASD spectrum]]
** [[spoiler:Tony Attwood]] is mentioned. If you already know who he is, then you know what's going on with [[spoiler:River]].
** Part of the code in the background when you prepare a memento says, "Step twice into the river of life." If you're familiar with philosophy, this is based on a quote from Heraclitus, a Greek philosopher who said, "No man ever steps in the same river twice."
* JerkAssWoobie: [[spoiler: Neil.]] Although it all depends on how you viewed his character and how you interpreted TheStinger.
* MagnificentBastard: The reactions of quite a few players to [[spoiler: Eva's BatmanGambit that, by removing River from Johnny's environment, that ''both'' would be motivated enough to qualify for NASA]].
* TearJerker: The whole game, really.
* TheWoobie: [[spoiler: Joey.]] Also River. And depending on how you interpret the implications, [[spoiler: Neil.]]
* UnfortunateImplications: Despite Asperger syndrome being depicted in a realistic, understanding, and sympathetic light, it's too unspeakable of to mention by name.
** Revealing what it is would immediately color the perception of the Internet, which has its own preconceived stereotypes about the condition due to rampant [[DisabilityAsAnExcuseForJerkassery "self-diagnosed" people online]]. By not bringing that up, it helps to simply show what it is, no baggage attached.