* CompleteMonster: [[spoiler: Luke, AKA Jim Jones]], is revealed to be one in ''Further''. Also, [[spoiler: Norman. And a bit of a stretch, but Lexy's parents]].
* DesignatedProtagonistSyndrome: Mary Ann, perhaps starting as early as ''Further'', but particularly from ''Sure of You'' onward.
* EnsembleDarkhorse: Michael and Mrs Madrigal, who started out as secondary characters in Mary Ann's sub-plots before graduating to their own story lines. After the hiatus they each receive a book dedicated to their stories. Michael in particular is often cited as "the most beloved of Maupin's creations", and sometimes even "the most beloved gay character in fiction". Quite the honor!
** Also D'orothea, whose return to the series was eagerly anticipated by a lot of fans, and seems to be much more popular than Mona, the character she was originally shown in relation to.
* HoYay: Michael and Brian have their moments. Quite deliberately too: Brian's secure enough to walk down the street with his arm around his gay friend and it not be an issue.
* LesYay: Mary Ann and [=DeDe=] become extremely close in ''Further'', with much HoldingHands or arm-squeezing. Towards the book's end, [=DeDe=] grabs Mary Ann's hand and kisses it.
* OneTrueThreesome: Mrs. Madrigal calls Michael, Brian, and Mary Ann her favorite couple.
* ReplacementScrappy: Prue Giroux, Mona's replacement in ''Further''. Stupid, selfish, and vaguely racist and homophobic, all in one package.
** The "new generation" from the post-hiatus books (many of them the now-grown children of the "first generation") are young people facing realistic modern-day problems - essentially mirroring Mary Ann, Michael, Brian, Mona, [=DeDe=] and D'or from the first six books. Unsurprisingly, their chapters are generally less popular than the ongoing tales of the older crowd from the originals, though most reviewers seemed to think they were merely average rather than outright terrible.
* TheScrappy: Mary Ann and Mona are less universally loved than a lot of the other characters, perhaps because they are shown becoming ''more'' selfish and self-absorbed as the series goes on. Contrasted with, say, Brian and [=DeDe=], who go from being self-centred and rude to genuinely caring and likable, it's not hard to see why a bit of antipathy might set in.
* {{Squick}}: The story Burke was investigating that gave him his amnesia? [[spoiler:A cult of cannibals]].
* StrangledByTheRedString: We never see the process by which Mary Ann and Brian fell in love, so their relationship in ''Further'' just seems to come out of nowhere.
** Particularly jarring since, at the end of ''More'', it's Brian and Mona who get together. ''Further'' might almost be seen to {{Retcon}} the situation, with Brian and Mary Ann an item, and no mention of Brian's history with Mona until ''Babycakes''.