* HilariousInHindsight: In light of [[Recap/SupernaturalS11E23AlphaAndOmega the Season 11 finale]], Sam's line [[spoiler: "Mom's gone. And she isn't coming back."]] is this.
* QuestionableCasting: Sam (Creator/JaredPadalecki) and Dean (Creator/JensenAckles) look nothing alike but there's no denying the actors have chemistry and act like brothers.