* AmericansHateTingle: The series had a pretty cold reception in the USA (it's the 12th lowest rated show on Anime News Network). The [[WidgetSeries widget]] nature of the show and the fact that the "straight" dub was the one aired on Creator/AdultSwim are probably the biggest reasons.
** For what it's worth, just about everyone (including the cast and crew at ADV) agrees that the gag dub is the superior version, in that it's actually watchable.
* HarsherInHindsight: The GagDub's slams against Music/MichaelJackson and James Gandolfini come off a bit mean these days since both men died unexpectedly.
* MemeticMutation: BELGIAN WAFFLES!!!!!
* TakeThat: While the original was mostly {{shoutout}}s, the GagDub skewered just about everything, [[SelfDeprecation including itself]].
** UsefulNotes/GeorgeWBush's administration is a frequent target.
--->''"Attention. Attention. Radar has detected an armed nuclear missil—I'm sorry, [[InsistentTerminology a 'weapon of mass destruction']] heading for our country."''
** ''So'' many jokes about gay culture any time the landlord is on screen.
* WhatDoYouMeanItsNotForKids: The commercials on Creator/AdultSwim made it pretty easy for viewers to mistake the show as the kids, until you see the words "Super" "Milk" "Chan" show up on a black screen. Plus the show is rated TV-14 (or TV-PG for the Vintage episodes).
** The Gag Dub makes it even worse, slapping a TV-MA for its [[ClusterFBomb frequent harsh]] [[PrecisionFStrike cursing]].
* WhatDoYouMeanItWasntMadeOnDrugs: There's a scene in the Anime that falls straight in to DerangedAnimation that ends with (in the GagDub) Hanage declaring the only explanation for the scene is "These drugs are fuckin' AWESOME"