* CriticalResearchFailure: In an episode where Michael tries to find out if his staff has been lying on their resumes, he confronts Paul with his claim that he has been involved in a Jordanian election, suggesting that it can't be right, since Jordan is a monarchy. While the king of Jordan does retain much personal power, the country has multi-party politics and the Jordanian House of Representatives is democratically elected.
* EpilepticTrees: James had already gotten fired last season and was on Mike's payroll as the "Deputy Deputy Mayor", so when Mike left..?
** James was re-hired as the Mayor's speech writer prior to Mike's departure, presumably due to budget cuts which meant they were understaffed.
** The closest they got to acknowledging the disappearances of James, Nikki, Janelle, and Stacy was in Season 5's "Smile", where the Mayor (while grieving over the death of his favorite dentist) expresses lament over the fact that some people who were important to him have left within the past few months. Granted, he doesn't mention any names, but let's just say he's talking about Stacy, Nikki, Janelle, James, and of course Mike.
* FunnyAneurysmMoment: "Age Against the Machine" features Charlie ultimately deciding that he's too old to party every night. If only Creator/CharlieSheen had come to that same conclusion...
* HarsherInHindsight: Carla Gugino's final episode has Mike being worried that his and Ashley's differing political views and competitiveness could result in the destruction of their relationship. Ashley assures him everything's fine, and their relationship can withstand anything. Seems heartwarming, at first, but ''the very next episode'', had Mike just been dumped by Ashley, and going through a HeroicBSOD. Damn....
* HilariousInHindsight: In one episode Mike and his crew accidentally hires an interpreter for deaf people, who fakes his sign language, angering the deaf community. This later happened in RealLife [[http://www.cbsnews.com/news/mandela-service-interpreter-for-deaf-accused-of-faking-it/ at Nelson Mandela's funeral in 2013]].
** From "The Spanish Prisoner." Caitlin tells Charlie, "You're so self-confident, so self-assured, with so little reason to be that way." Considering the kind of smug {{Cloudcuckoolander}} Sheen would later become ("Tiger Blood", "Winning")...
** On "How to Bury a Millionaire", Paul wins the top prize on Series/WhoWantsToBeAMillionaire. Three days after the episode's original air date, John Carpenter became the first top prize winner on the real show.
* HoYayShipping: Stuart & Carter eventually started acting more and more like this. Unusual mainly because Carter ''was'' gay. Became very, ''very'' close to canon at times. (Carter's nightmarish ImagineSpot about ending up with Stuart, miserable together until death, is probably a crowning example.)
** More and more? It already started in the second episode, with Stuart asking Carter on a date.
** Carter eventually starts questioning whether or not his feelings for Stuart are romantic. Asked to testify that he isn't in love with Stuart, he stammers that he "doesn't know" ... and also doesn't actually deny that they've been sleeping together.
* RetroactiveRecognition: [[Series/{{Firefly}} Malcolm Reynolds]] was a [[spoiler:gay]] personal trainer in New York.
** [[Film/TheSpirit Denny Colt]] appeared in one episode as a nudist campaigning for naturist's rights.
** Jorge Garcia (Hurley from ''Series/{{Lost}}'') appears briefly as a taxi driver in one of Michael J. Fox's TheBusCameBack episodes.
** Fans of ''Once Upon a Time'' will recognize Lana Parilla as Charlie's secretary Angie in Season 5.
* TheScrappy: Caitlin. To a lesser extent Charlie qualify too.
* {{Tearjerker}}: The fourth season finale certainly qualifies. This is emphasised by the fact that the show's usually upbeat music is replaced with sad motifs and themes, and there is a reprisal of 'Everybody Gets What They Deserve' by The Churchills, which was used in a heartwarming moment in Season 3.
** It's even more of a tearjerker if you consider that Michael J. Fox only left because of Parkinson's. Otherwise the show might have continued.