* AnticlimaxBoss: [[GoodBadBugs Amusingly]], the ''final two bosses'' can both be taken down before the fight even begins, due to them both appearing on the map before the battle and still being damagable in this state. See [[http://www.youtube.com/watch?v=aaqOZbivZy4 here]] and [[http://www.youtube.com/watch?v=p3D5UDohVgk here.]]
* DemonicSpiders: The Y.E.T.I. on Planet Greblin. They are everywhere, highly durable, annoyingly cheap, and will do their best to prevent you from getting moonstones, often attacking in large groups. Some developers admitted they were coded in a rush and break some of the enemy guidelines they set, like short attack telegraphing and constantly attacking from behind. This actually got a MedalOfDishonor made for the studio, called the "Snowbeast Award" for whoever made the worst thing in a game made the previous year.
* DesignatedHero: Angela Cross. After TheReveal, she's treated as a misunderstood hero who's been thwarted by unsuspecting dupes. Though she ''was'' a WellIntentionedExtremist, her crimes up to this point include kidnapping and holding Clank hostage, repeatedly trying to kill Ratchet, and generally just acting like an actual villain. Though we learn she was forced to resort to extreme measures to stop Fizzwidget from releasing the Protopet in its current state when he fired her and refused to listen to her concerns, her actions cross the line from extremism to villainy quite easily.
* EvenBetterSequel: Quite apart from Ratchet's improvement in professionalism and character, the weapons are more serious yet still creative, the number of worlds and gameplay elements increased, RPG-like elements such as the upgrade features were added, and the wrench controls became a lot less cumbersome. There's also a ton of new features and gadgetry, and even the Clank sections underwent some major changes.
** The Bouncer can be this in all but the very last levels. It does massive damage on the initial blast and lets loose mini-bombs that seek out remaining targets and explode for additional damage. Its only shortcoming is that it has a hard time hitting flying enemies, but anything on the ground is toast. The final boss can be killed in a couple minutes just by bombarding it with Bouncer bombs.
** The Plasma Coil is an okay weapon at first, hitting a primary target for decent damage and shocking nearby enemies when it hits. However, it upgrades into the Plasma Storm, which fires an orb of electricity that shoots out lightning at anything it passes. A single Plasma Storm shot is enough to clear entire rooms full of enemies.
** The Shield Charger is a magnificent example of MagikarpPower. It's initially weak and almost useless, it protects you from damage and does minor damage to enemies you touch. Stick with it though and it becomes the Tesla Barrier, which shoots lightning to zap any enemy that gets close to you, and it does good damage with it too. It noticeably helps against the above mentioned DemonicSpider Y.E.T.I.
** As last time, the [=RYNO II=] pretty much annihilates anything you aim it at.
** The Sheepinator makes fighting Protopets hilariously easy, killing them without using any ammo whatsoever (so you could save your ammo for the harder enemies of the level). The Black Sheepinator is even better, killing them faster and also turning them into sheep that ''explode''.
* GoddamnedBats: The Protopets. They keep reproducing if you don't get every single one of them and you often encounter them in groups.
* GoddamnedBoss: Megapede is not difficult to beat, but it has a large health bar, moves around the arena all the time, deploys irritating bombs en masse, and when whittled down by a powerful weapon, deploys mini-tanks with a difficult-to-avoid attack. The [=RYNO II=] doesn't help in this case because it keeps missing it, so you'll need weapons with Lock-On Mods.
* GoodBadBug: Using the thruster boots on the ice planet while being attacked by the Yeti's can cause Ratchet to dissapear with only his shoes, helmet and clank being visible. In this state he is immune to damage, which means you can run around collecting Moonstones or beating Yeti's at your pleasure.
* HoYay: In the first cutscene, Ratchet is told he will learn a number of bizarre skills to become a commando, including ballroom dancing. Complete with an image of him in a fancy suit, dancing with a dress-clad Clank.
* ItWasHisSled: The Unknown Thief's true identity, being a female [[spoiler: lombax]] named Angela Cross. Of course, the series' "official wiki" [[LateArrivalSpoiler does not care with the spoiler policy]], so only a few fans would really ''not'' know about this before playing the game for the first time.
* MoralEventHorizon: [[spoiler: Captain Qwark, much like in in the first game for siding with a planet killer for publicity and money, comes dangerously close to crossing this line again in this game, by kidnapping and impersonating a corporate CEO, and willingly unleashing a killer pet upon billions of lives so he could [[EngineeredHeroics avert the threat and take credit for it]], and attempting to frame Ratchet, Clank and Angela for the catastrophe. And barring his plan [[HoistByHisOwnPetard horribly backfiring on him and getting him eaten alive]], and being stuck in a humiliating, painful disposition as a Megacorp test dummy, he practically [[KarmaHoudini gets off scot free.]] Fortunately, he manages to redeem himself in the next game]]
* TheScrappy: The New Age Mystic for being generally unhelpful and requiring the hard-to-get Moonstones just to do something.
** The "Old Skool" skill point has been getting this reputation, but [[GameBreakingBug probably for the wrong reasons]]. It's a pretty tricky skill point in and of itself: requiring you to kill everything in a particular level (and a fairly long, two-segment one at that) using only Ratchet and Clank 1 weapons, [[SoLastSeason which are much weaker compared to the new RC2 ones, and can't be upgraded]]. But to add insult to injury, the skill point is glitched in the HD re-release, meaning it mightn't show up even if you do everything right!
** The "Wrench Ninja II" skill point is just as bad, as the enemies on that planet will often kill each other before you even reach them, and it's nigh impossible to hit some enemies without getting a few scars for your trouble.
* ThatOneSidequest: Collecting the moonstones on Grelbin, and [[LastLousyPoint not just because there's no way to tell where to look if you miss one or two]]. The crystal-gathering sidequest on Tabora had similar problems, but at least the enemies there were manageable.
* WoobieSpecies: The one-eyed robots seemingly can't catch a break. They get blown up in a commercial and eaten by mutant squirrels on Todano, killed by security robots on Aranos, and massacred on their home planet, Damosel. Two skill points involve keeping them alive despite the hordes of enemies waiting to get them.