* ArcFatigue: Unfortunately went down this route after sometime, since the arc later separated into several mini-arcs for a while until ending in ''War of the Supermen''.
* CompleteMonster: Reactron, a SociopathicSoldier who threatens to rape Supergirl, kills a number of Kryptonians, including her father, tries to murder Mon-El in order to frame Krypton, depowers Supergirl and Flamebird and tries to sexually assault them, and finally blows himself up in the heart of Kandor, killing Supergirl's mother and ninety thousand+ other Kryptonians, gloating the whole time.
** Brainiac, who destroys one planet, tries to destroy Earth, kills several thousand Kryptonians, kills Jonathan Kent, and attempts to melt Superman's brain by feeding several world's worth of information into it.
* MagnificentBastard: Luthor is at his best here, cooperating with Lane to achieve a goal he would have worked towards anyway, playing Brainiac and Superman alike to his own ends, and ultimately being rewarded for his role in [[spoiler:destroying New Krypton]].
* MoralEventHorizon: Reactron crosses it in his first appearance, when he kills Supergirl's father while threatening to sexually assault her. General Lane does it when he transforms his daughter Lucy into a superweapon.