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* HarsherInHindsight: [[https://www.bonequest.com/2510 No. 2,510]], published in 2005, features Deuce saying that by 2020, touching other people "will be a death sentence", and Spigot responding by saying he is going to jerk off. Deuce's comments took on a whole new meaning when 2020 would see a COVID-19 coronavirus pandemic that would be very contagious and sometimes deadly, which resulted in several governments to emphasize social distancing to slow down the virus's spread.
* SoBadItsGood: To some people. One of the authors actually ''explicitly stated'' that this was one of the points of the comic.
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