** Amy from the Anime Club strips.
** The Fox from the rabbit strips.
* FunnyAneurysmMoment: The [[MemeticMutation famous]] [[http://gunshowcomic.com/648 "This Is Fine"]] strip can be harder to find funny after reading [[https://thenib.com/this-is-not-fine?t=recent its sequel]], especially since it was made in response to the plethora of depressing events that happened in 2016.
* SugarWiki/HeartwarmingMoments: [[http://gunshowcomic.com/200 The crab saga]], and the end of the [[http://gunshowcomic.com/271 Ghost Ship]].
** [[http://gunshowcomic.com/471 "DARE YOU ENTER MY MAGICAL REALM?"]] has become [[http://1d4chan.org/wiki/Magical_realm tabletop shorthand]] for fetishistic [=GMs=] and, more generally, for when the more fetishistic areas of AuthorAppeal run a ''little'' too rampant.
** A more mainstream example: the first two panels of [[http://gunshowcomic.com/648 "On Fire"]], a.k.a. the "This is Fine" denial dog.
** "I GUESS!" from [[http://www.gunshowcomic.com/367 Cat Lunch Break]] is fairly popular as a reaction image.
* NightmareFuel: Frequently. Example: [[http://gunshowcomic.com/334 The Farm House]].
** Occasionally, though "[[http://gunshowcomic.com/700 The Dog's Sins]]" stands out.
** And "On Fire"'s own sequel comic, "[[https://thenib.com/this-is-not-fine?t=recent This is Not Fine]]". It may have been interesting to see Question Hound finally start discovering the elephant in the room, but in the wake of some of the more depressing news of 2016, it's way more than poignant.
* UglyCute: [[http://gunshowcomic.com/398 Skeleton baby]].