* FoeYay: Cain and Jizabel.
* HoYay: Cain and Riff, most obviously, along with Jizabel and Cassian... and Cassandra. There's also some between Oscar and Cain, but that's mostly played for laughs.
* HollywoodHomely: Drew in the ''Scold's Bridle'' story arc is supposed to be unattractive, which in the art style's terms translates to red hair, glasses and a slightly curvier build than the other female characters.
* MagnificentBastard: Cain, [[spoiler:Alexis, and ultimately, Augusta]].
* NightmareFuel: The sheer creepiness of how all the gory murders Cain investigates follow nursery rhymes that are already rather disturbing. Then, there's [[http://www.mangahere.com/manga/count_cain/v03/c002/5.html this]].
* TearJerker: ''Everywhere,'' especially the last three volumes.