!!For the Board Game
* MemeticMutation: "It was [person] in the [location] with the [weapon]"
* ReplacementScrappy: Dr. Orchid, for Mrs. White. It ''really'' doesn't help that Hasbro put it in her backstory that she's the [[RememberTheNewGuy adopted daughter of Dr. Black]], and that the character she replaced was [[spoiler:KilledOffForReal]].
* TheyChangedItNowItSucks: The 2008 "modernized" version of the game garnered this reaction to some, which is probably why said changes were dialed back in the newer releases of the game to the classic version.
!!For the Movie
** There's a good deal of debate surrounding Mr. Green's actual sexuality. [[spoiler:In the third ending his last line is "I'm going home to sleep with my wife." A joke that he was straight all along, or is he just keeping up the facade now that other people are around?]] Though considering he outs himself, the latter might be unlikely.
** Wadsworth. [[spoiler:In the Scarlet and Peacock endings where he's working for the FBI is he deliberately making it harder on Boddy's victims and not protecting the accomplices out of some sense of justice? In the ending where he's Mr. Boddy is he behaving the way he does throughout the movie to torment his victims?]]
* SugarWiki/AwesomeMusic: John Morris' score [[https://www.youtube.com/watch?v=hAUeEGdmFs4 is often criminally overlooked]].
* BetterOnDVD: With its 3 endings, which not only heavily encourage re-watching to work out the various solutions, but also make a trip to a theater showing only one ending less satisfying, ''Clue'' seems specially designed for [=DVD=] viewing. Even though it was made almost a decade before the medium was invented.
** Of course when it was released on VHS, all three endings were shown back to back like it is available on the DVD. However the DVD has the option to choose a random ending.
** The way that they did it was that the multiple endings were supposed to be spread out over the movie's run, or mixed up and shown randomly... so that if you wanted to see the other two endings, you had to ''go see the movie again.'' Twice. At least.
** Seeing the film again, one will notice Wadsworth's reaction to Mr. Green revealing his blackmail without letting Wadsworth out him. He's confused and checks the blackmail to see if Green's there, [[spoiler:the blackmail unfamiliar to him and possibly planted by the FBI.]]
** "Da-da-da-dum-dum-dum! I! Am! Your singing telegram--" *BANG*
** Also:"...Oh, life could be a dream (sh-boom)...If I could take you up in paradise up above (sh-boom)..."
** "I said shake, rattle and roll! I said shake, rattle and roll!"
* EnsembleDarkhorse: Yvette (for [[MsFanservice obvious reasons]]).
* HilariousInHindsight: Creator/RogerEbert offered this in his review:
--> Here's my suggestion: Since this movie is so short anyway (88 minutes), why doesn't the studio abandon the ridiculous multiple-ending scheme and show all three endings at every theater? It would be more fun that way.
* IncrediblyLamePun: Wadsworth's pun about Hoover
-->'''Professor Plum''': But is the FBI in the habit of cleaning up after multiple murders?
-->'''Wadsworth''': Of course. Why do think itís run by a man called Hoover?
** Wadsworth, the butler. In all three endings. [[spoiler:In the first two endings Wadsworth, actually an FBI agent, set up the entire scheme in order to implicate the killer in a conspiracy and take her down. In the third ending, Wadsworth is actually Mr. Boddy and used the guests to kill off the informants who gave him everything he used to blackmail them; with each of the guests now guilty of murder and his informants all dead, he then plans to extort even '''more''' blackmail money from them.]]
** Mr. Green in the third. [[spoiler:He successfully passes as one of the blackmail victims and passes for a clumsy fool and homosexual. In truth, he IS the FBI agent, shoots Wadsworth when he reveals himself, has all the others arrested, then announces that he is "Going home to sleep with his wife!"]].
** "FLAMES on the side of my face"
** "That's how it could have ended. Here's what really happened."
** "And, to make a long story short (TOO LATE)..."
** "Communism was just a red herring."
* OneSceneWonder: Jane Wiedlin as "your singing telegram (BANG!)".