* AssPull: [[spoiler: The organisms covering North America Ascending to a higher reality.]] Nothing about this is alluded to until a InfoDump by MrExposition near the end.
* NightmareFuel: Vergil's girlfriend is still able to speak... as her body is slowly melting down the shower drain.
** Vergil himself is found laying in a bath filled with pink water by his friend Edward, claiming he's been in there "an hour, hour and a half". Considering the fact the noocytes fuck with your sense of time and space, it's possible that Vergil was laying in there for ''over 12 hours''. And the worst part? [[spoiler:The pink water isn't bubble bath. It's ''Vergil's body dissolving''.]]