* CrackPairing: Some fan pics in both Website/{{Pixiv}} and Website/DeviantArt paired the Protagonist, with, of all people, the Archangel.
* FanNickname: The protagonist is usually referred to as Dextera XIII. Also, Koriel XIII.
* GameBreaker: The fact that you can save items between runs makes a few possible.
** With an Addition Box and two Split Brands, you can duplicate an infinite number of any item in the game.
** Vampire Swords will randomly gain a weapon level and heal you. Once you find one, you won't need any other weapon, save perhaps a Triple E(lemental) Sword for the Bonus Dungeons.
* NightmareFuel: The Neuro Tower, in both games. Being a confined, dungeon-like space with all these Meta-Beings, and not knowing what's in store when you advance to the next level... first-person or third-person perspective, it's a creepy place to say the least.
** Quite a few of the characters themselves. The Horned Girl's lack of thoughts/personality, particularly that moment when you realize she's saying what ''you're'' thinking. Longneck's creepy masochistic suicidal attitude. The Archangel's treatment of you, impaled on a spike of a Consciousness Orb, looking dead in the original but clearly awake/alive in the remake. The Protagonist being the only one who looks/acts like an actual human being in the game.
** [[spoiler:When characters start burying themselves.]]
** [[spoiler: The Boxbearer's breakdown, he and the revelation that he killed his own daughter (The Bagged One) in a fit of madness. He become so distraught he deluded himself into thinking his empty box contained his daughter's soul.]]
** Once you learn the truth of the Meta-beings, it'll frighten you to think [[spoiler:they were once human]]. Even worse is when you read the Meta-beings' baroques, which are stories of how they became the way they were. But even then, many are ''very'' creepy, with [[http://www.atlus.com/baroque/ps2/ikei/ikei2/ikei16.htm Bubugel]] and [[http://www.atlus.com/baroque/ps2/ikei/ikei2/ikei06.htm Nicl & Nicr]] (the worst case of LoveHurts) making the rest rather tame.
* ThatOneBoss: The only four bosses aren't required to beat the game - in fact, they only show up after the main storyline is ended. But boy are they HARD. Even worse, after you beat them in the Neuro Tower, [[spoiler:they become normal enemies in the Coffin Guy's bonus dungeons]].
* UncannyValley: Most creatures in the game fall under this, to some. The remake making everything slightly more cartoonish may make it even worse.
** Its kinda strange how some characters like the Protagonist, Archangel and the Absolute God are drawn in typical anime style, yet others like the Coffin man are drawn in a more realistic manner.