* AssPull: The anime's SuddenDownerEnding as we only learn after Bagi's unexplained absence and TimeSkip she had "matured yet again", resulting in the sudden loss of much of her intelligence. She had changed into a wild feral animal. Whether this was a case of WriterCopOut, ExecutiveMeddling, or CreatorBreakdown is unclear. Osamu definitely wanted to convey the message that [[ScienceIsBad man needs to learn that meddling with nature is morally wrong]], a noble message. Regrettably, poorly executed one in the final arc of the story at the expense of a main character's [[{{Deconstruction}} personality and development]].
* MisaimedFandom: The movie was originally made in opposition to [=DNA=] recomposition researches and to warn against the dangers of meddling with nature. Ironically, it became PopularWithFurries to a degree, and the titular character being an anthropomorphic MsFanservice only made it worse.
* PopularWithFurries: With the giant talking cat-woman in a leotard, it’s kinda obvious.

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