!!!The strip:
* PeripheryDemographic: The strip is popular even among those who aren't parents including, apparently, [[http://www.enquirer.com/columns/kiese/2000/07/27/jki_kiesewetter_network.html teenage girls]].

!!!The series:
* AudienceAlienatingPremise: Unlike the strip, the show was fused with crass humor and language aimed squarely at older audiences, but this seemed to turn off fans of the actual comic, and the show didn't have much of an audience to grab outside of that fanbase.
* TheyJustDidntCare / ExecutiveMeddling: Let this be a lesson to all TV executives out there: Adapting a family-friendly comic strip with a huge fanbase, making it a HotterAndSexier ''Simpsons'' clone, shoehorning in a new cast who [[SpotlightStealingSquad takes the lion's share of the plot at the MacPhersons' expense]], making Zoe a baby, even though she was a toddler in the strip at the time and Hammie had just been born, and [[ArsonMurderAndJaywalking putting it on a mediocre channel like The WB]] is '''''NOT''''' going to win over audiences.