* JerkassWoobie: [[spoiler: Leviathan apparently had her parents murdered, was held hostage for ''decades'' during her Indoctrination that turned her into a Reaper, was abandoned by Harbinger for about a billion years ([[TimeAbyss literally]]), and finally BroughtDownToNormal by Shepard and imprisoned.]]
** [[spoiler: Councilor Sparatus, after his wife and children are killed when the Reapers hit Palaven.]]
* TheWoobie: Nassana Dantius, in addition to AdaptationalHeroism, has this: she's told her beloved sister was a slaver in the worst possible way, has a breakdown, and is nearly shot by Shepard. When she's next seen, she's living in paranoia of her own family trying to kill her and hasn't bathed in months, though Shepard manages to [[SparedByTheAdaptation save her from Thane this time]]. She's then sent to mental health care off of Illium. [[spoiler:Which saves her life when the Reapers invade.]]