* In ''WebAnimation/SpoilsburyToastBoy'', the doctor beetle explains to [[IllGirl Liache]] that "mucus is a living thing" and "it has a certain degree of intelligence." [[spoiler:The beetles later drown Liache when her mucus tells them she doesn't deserve to breathe.]]
* In the ''GlobalGuardiansPBEMUniverse'', while intelligent apes have been given full civil rights, robots, androids, and other artificial intelligences are still not considered people in the legal sense even though they cannot be harmed with impunity (property laws come into consideration). Demons, the undead, and most other forms of monster are free targets, however.
* Averted for dark laughs in the last segment of the [[http://www.youtube.com/watch?v=IYnsfV5N2n8 first]] ''[[ASDFMovie asdfmovie]]''. The guy is horrified when he [[spoiler:unwittingly stabs a sapient living cake [[IHaveAFamily (who has a wife and children)]], causing the cake to be DrivenToSuicide]].
* Disturbingly deconstructed [[http://www.newgrounds.com/portal/view/541886 here]]
* [[http://vimeo.com/31894179 Rosa]]has cyborgs that really blurs the line between human and nonhuman [[spoiler:by makeing the red eyed cyborgs seem inhuman and like cold hearted machines, where the Rosa is shown in a sympathetic light]]
* ''Literature/TalesOfMU'' makes this a plot point, especially when Mackenzie is trapped in [[DungeonCrawling the Labyrinth]] and runs across the [[YouAllMeetInAnInn adventuring party]], including a [[WhiteMage priestess]] [[TechnicalPacifist of the goddess of peace]] and is shot in the shoulder. The resulting argument among the party isn't whether they should save the story's [[HalfHumanHybrid half]]-[[OurDemonsAreDifferent demon]] protagonist, but whether they should [[MurderIsTheBestSolution kill her now]], or [[WhatTheHellHero let her bleed to death after they abandon her]].
* ''WebVideo/{{Kara}}'' deals with this.
* Deconstructed in this [[http://www.youtube.com/watch?v=7tuZtbca-V4&feature=relmfu Video Game Confessions]] which reimagines Samus as a violent torturer and serial killer. She asks "Why is it that when you kill an alien from another world, you're considered a hero?"
* Played for laughs in a LetsPlay/TheRunawayGuys playthrough of Mario Party during the mini game Shy Guy Says when LetsPlay/ProtonJon is horrified when the Shy Guy leaves Wario to drown in the ocean, but ignores Yoshi when the same thing happens to him right afterwards.
--> '''Chuggaa''': ''And you say I'm racist?''
--> '''Jon''': ''Ra... How is that racist? It's a dinosaur!''
--> '''Chuggaa''': ''Dinosaurs are people too.''
--> '''Jon''': ''No, they're not! They're dinosaurs, that's why we call them dinosaurs!''
* When Straizo uses the Ripple on Dio's elite zombies during a scene in ''WebVideo/VaguelyRecallingJoJo'', he spares Page because Page had an almost human-like appearance. Also, Page looked like Pesci, who will make an appearance in Vento Aureo.
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