An AnimatedAdaptation of ''Film/TheToxicAvenger'' film series by Creator/{{Troma}}, which originally ran from 1990 to 1991.

After a freak accident involving toxic waste turns one Melvin Junko into a hideously deformed creature of super-human size and strength, he becomes a superhero known as Toxie, who is able to sense and thwart evil wherever it turns up. He is soon joined by like-minded freaks as he defends his hometown Tromaville from the nefarious schemes of Dr. Killemoff.

!!We are the toxic -- examples! We are the toxic -- examples!

* AdaptationNameChange: Downplayed. Instead of the Toxic Avenger, Toxie's full designation is Toxic Crusader.
* AdaptationalHeroism: This version of Toxie is content with just beating up the bad guys, instead of mutilating, disemboweling and otherwise killing them in horrifying ways like in the movies.
* AttractiveBentGender: When Nozone sees Psycho disguised as a woman in "A Site for Sore Eyes!", he instantly falls in love with "her", and spends the rest of the episode lovesick.
* BananaPeel: In "The Snail Must Go Through!", race car driver Crash Shelby falls out of a bridge due to a banana peel getting under one of his tires. He falls on a barge filled with snails, which combined with his car's motor oil, turns him into the mutant superhero Snailman.
* BarefootCartoonAnimal: Junkyard, the humanoid mutant dog, doesn't wear shoes.
* BattleCry: Parodied, then played straight. Toxie's original battle cry is "I hope I don't get hurt!", but he later changes it to "It's clean-up time!"
* BigBad: Dr. Killemoff, who seeks to pollute Tromaville to the point that it can be invaded by his fellow bug-people from the planet Smogula.
* TheCassandra: Dr. Killemoff's flunkie Psycho is this in a nutshell: his entire purpose is to point out to his boss how his latest plan can go wrong, usually involving really unlikely circumstances that nevertheless always end up happening and yet Dr. Killemoff never listens to him, despite his predictions having always been right.
* CompilationMovie: Several episodes were edited together to create ''Toxic Crusaders: The Movie'' that was released on video in 1997.
* DeadpanSnarker: Psycho tends to make snide remarks about Bonehead's stupidity and Dr. Killemoff's continued refusal to heed his predictions of how the Toxic Crusaders will ruin their schemes.
* DreadfulMusician: Toxie's girlfriend Yvonne often comes up with a ditty with her accordion, which is only enjoyed by her boyfriend.
* EveryoneCallsHimBarkeep: Toxie's mother is called Mom by Toxie, and "Toxie's Mom" by everyone else.
* EvilInc: Apocalypse Inc., run by over-polluting Dr. Killemoff for the behalf of his alien brethren.
* {{Expy}}: Some of the characters in the animated series are loosely based on characters from the movies.
** Yvonne fulfills Sara/Claire's role as Toxie's blonde love interest, though she's near-sighted instead of blind.
** Bonehead is based on Bozo and Slug from the first film and even looks like the latter prior to his mutation.
** Mayor Max Grody is similar to Mayor Belgoody from the first movie due to both being the fat corrupt mayors of Tromaville.
* FatBastard: Grody, the overweight and corrupt mayor of Tromaville, who is in cahoots with Apocalypse Inc.
* FreakyFridayFlip: "That's No Villain, That's My Mom" had Dr. Killemoff switch minds with Toxie's Mom.
* GettingCrapPastTheRadar:
** In the first episode, Melvin is asked what he has planned for the evening. His schedule includes a half-hour set aside to "wax his chicken." Bimbette also offers that they "get to know each other better, [[LampshadedDoubleEntendre know what I mean]]".
** In "A Sight for Sore Eyes", Bonehead and Psycho try to prevent Toxie from going near the toxic dump where the Toxic Crusaders live by disguising themselves as dignitaries from a country called "Barebutta". Toxie even addresses them both as "your heinie-ness".
** In "Toxie Ties The Knot", Czar Zosta's daughter Princess Gerba is kidnapped by Mayor Grody. Thinking that someone is throwing her a bachelorette party, when the Mayor shows up in a bug costume, she states that he must be the male stripper. Also, when Toxie catches Gerba after she starts to fall for Grody, she informs Toxie that Grody tried to take advantage of her.
** In "Nab That Toxie Cab", Yvonne visits a fortune teller named Madame Gazonga. "Gazongas" happens to be slang for large breasts.
* GladIThoughtOfIt: In the episode "Club Fred", Psycho sarcastically suggests that they prevent the Toxic Crusaders from interfering with their plan by sending them on a tropical vacation. Dr. Killemoff seriously considers the idea and takes full credit for it.
* GlassShatteringSound: Yvonne's dreadful musicianship extends to breaking glass with her singing when she's heart-broken about Toxie marrying someone else in "Toxie Ties The Knot!".
* GoneHorriblyRight: Pretty much all of the Toxic Crusaders' inventions to help clean up Tromaville in "Pollution Solution" has some unexpected side effect. For instance, Headbanger's graffiti remover also removes the print from newspapers and No-Zone's aluminum detector mistakenly attracts an old man's canned groceries and the empty cans used on the limo of some newlyweds.
* GreaterScopeVillain: The Smogulan leader Czar Zosta, who is Dr. Killemoff's boss and the reason he's trying to pollute Earth to make it fit for Smogulans to inhabit.
* GreenAesop: The Toxic Crusaders fight against Apocalypse Inc. and their plans for polluting the Earth.
* GreenThumb: Major Disaster could not only control plants of the organism variety, but, in "Pollution Solution", power plants as well.
* {{Hologram}}: Dr. Killemoff and his boss Czar Zosta often have discussions through holographic projections, which can sometimes do even physical stuff.
* ILoveNuclearPower: Some of the main characters became super-powerful (as well as hideously deformed) when they were exposed to radioactive waste in separate unlikely accidents.
* IWantGrandkids: Toxie's mother mentions that she wants to have grandchildren in "Toxie Ties the Knot".
* IWarnedYou: Psycho, the minion {{Seer}} of Dr. Killemoff, usually says this after his CassandraTruth gets blown off by him as ridiculous and the good guys win.
* InsistentTerminology:
** Instead of "mutant", pretty much every individual mutated by toxic waste in this series is described as "a hideously deformed creature of superhuman size and strength.
** Killemoff will alway-''"That's '''Doctor''' Killemoff!"''
* IslandBase: Dr. Killemoff's base of operations, the ever-polluted and contaminated Island City.
* LighterAndSofter: Being a children's cartoon based on an R-rated film series, a lot of details obviously had to be watered down and censored. Most notably, Toxie doesn't kill any of the bad guys this time.
* LivingWeapon: The incident that turned Toxie the superhero he is now also turned his trusty mop into a living thing, which doesn't just clean the floor by itself, it also helps in fights.
* MeaningfulName: Bonehead's mutation gives him a skeletal appearance. He also isn't very bright.
* MediumAwareness: Much like [[WesternAnimation/TeenageMutantNinjaTurtles1987 another lighthearted cartoon adaptation by Murakami-Wolf-Swenson]], there are a lot of jokes involving the characters breaking the fourth wall and being aware that they're in a cartoon, like when Toxie notices that the background music has changed in the first episode.
* {{Mooks}}: Dr. Killemoff's Radiation Rangers, who all wear yellow hazmat suits (even though they're all apparently robots).
* MortonsFork: While only done as a quick gag, Junkyard unknowingly inflicts one on the dogs of Tromaville in "Pollution Solution". He does his part in making Tromaville more ecologically sound by appearing on a PSA where he tells dogs not to hike their legs when they feel the urge. Since dogs pretty much pee anywhere when not reprimanded by their owners, the only alternative would be for the dogs to suffer from being forced to hold it all the time and risk getting bladder infections and other serious health problems.
* MultiarmedAndDangerous: Dr. Killemoff, even in his disguise, has two sets of arms, a trait shared by the rest of his fellow Smogulans.
* MultipleHeadCase: Headbanger. He's a mutated freak with two heads who each control their side of the body. One head's a hideous MadScientist; the other's an oafish SurferDude. The body itself is kinda lopsided since the surfer's half of the body is rippling with muscle, whereas the scientist's is shriveled and emaciated.
* {{Mutants}}: The titular Crusaders and several one-shot characters were mutated by exposure to toxic waste.
* NamesToRunAwayFromReallyFast: Main villain's name comes from the phrase "kill 'em off", what more there is to say?
* NarrationEcho: Inverted in "Club Fred"; Toxie, in his role as the narrator, keeps repeating everything Dr. Killemoff says until he's told to shut up.
-->'''Dr. Killemoff''': Soon, hordes of pollution-breathing aliens from the planet Smogula will be arriving to take over Tromaville!\\
'''Narrator''': Soon, hordes of pollution-breathing aliens from the planet Smogula would be arriving to take over Tromaville!\\
'''Dr. Killemoff''': (angrily, towards the camera) IS THERE AN ECHO IN HERE?!
* NonMammalMammaries: It is shown in the episode "Toxie ties the Knot" that female members of the insectoid Smogulan race have breasts.
* NotThatKindOfDoctor: Dr. Killemoff in "Mr. Earth - Superhero!" yells this at the eponymous hero of the episode when he asks him if he could look into his neck-pains.
* OncePerEpisode: Every episode features a bit where Dr. Killemoff describes his EvilPlan of the week, prompting his mook Psycho to [[CassandraTruth always respond]] with "But what if [describes what happens in the rest of the episode]?" "Ridiculous! That could ''never'' happen!"
* PrankDate: Bonehead's girl Bimbette lures Melvin into one during the first episode, asking for him to meet her later in a pink tutu. It's all just a ruse to lure Melvin into being mocked by a bunch of other people. And then comes the accident that turns him into Toxie.
* ShearMenace: The incident that turned Mowerman into a mutant gave his right hand a pair of permanent garden shears. This leads to show's heroes calling him a mutant of "shear size and strength".
* ShoutOut:
** "[[Theatre/{{Hamlet}} There's something rotten]] in the state of UsefulNotes/NewJersey!"
** The title of the episode for "Invasion of the Biddy Snatchers" is based on ''[[Film/InvasionOfTheBodySnatchers1956 Invasion of the Body Snatchers]]''.
* SlimeSnailsAndMutantTails: Hideous mutants and toxic waste is used to try and appeal to kids.
* StandardizedLeader: Toxie is turned into this. He is big, strong, ugly, and has a sort of spider-sense. All the other Crusaders are also big, strong, and ugly, plus they have quirky, unique, useful powers.
* SuperStrength: Turns out that the bumbling superhero-wannabe Mr. Earth does have a super power, his strength (though he'd prefer x-ray vision).
-->'''Mr. Earth:''' I told you I was strong!\\
'''Nozone:''' But not superhumanly strong!
* SurferDude: Fender talks like a California surfer and even wears swimming trunks and sunglasses.
%%* TeenageMutantSamuraiWombats
* TheyCallMeMisterTibbs: Dr. Killemoff insists that everyone refrain from addressing him without the "Dr." in front of his surname.
* TitleDrop: "Invasion of the Biddy Snatchers" has General [=GarBage=] and Toxie both mention the episode's title, complete with the title appearing onscreen as they say it.
* ToxicInc: Apocalypse Incorporated's only purpose is to pollute.
* ToxicWasteCanDoAnything: Toxic waste not only provides Toxie with his powers, but perfectly fuses a man and a dog into a [[HybridMonster hybrid were-creature-like being]] (that being Junkyard: the rest of Toxie's companions were changed by exposure to radioactive materials), and then going even further by empowering a buried junked car(!) and a mop (!!).
* TwoBeingsOneBody:
** Surf-dude delivery boy "Fender" and mad scientist "Dr. Bender" accidentally fuse together forming the new hero... Headbanger.
** Junkyard also qualifies: a homeless man who takes shelter with a [[ExactlyWhatItSaysOnTheTin junkyard dog]] whose kennel was covered in toxic waste. Add [[LightningCanDoAnything one bolt of lightning]], and their molecules merged into a [[BeastMan humanoid dog]].