* [[spoiler:Terrence]] in ''{{KateModern}}'' -- goes from smug, quietly intimidating badass in series 1 to raving, giggling psychopath by the end of "Precious Blood".
** The Shadow and [[spoiler:Rupert van Helden]] have also suffered this by ''The Last Work''.
* In ''WebVideo/DoctorHorriblesSingAlongBlog'', the main character is shown as a TechnicalPacifist and IneffectualSympatheticVillain who states that killing isn't his style. However once his JerkJock archnemesis Captain Hammer states that he's going to steal the girl of his dreams just to torture him, he then goes into a VillainSong where he swears to kill him. This is followed in rapid succession by Captain Hammer's own breakdown when he is made to feel pain for the first time in his life (it's hard to call it a ''[[HeroicBSOD Heroic]]'' [[HeroicBSOD BSOD]] when he's shown to be just as evil as the protagonist), and a second, deeper one from Dr. Horrible when his victory coincides with [[spoiler:the death of his LoveInterest]].
* In ''LostBoysOfTheCascades'', [[spoiler: Barry]] suffers a villainous breakdown after his attempt to frame the Klamath Indians for [[spoiler: murdering Jennie, Troy, and Dylan]] falls apart due to [[spoiler: Troy surviving and telling the truth]].
* In ''TheSpoonyExperiment'' review of ''VideoGame/StreetFighter2010'', Doctor Insano suffers a breakdown after failing to create the ultimate being (instead producing a cute pink blob thing). He begins crying about how his science never works and nobody loves him before his new "son" cheers him up.
* [[BigBad Dio]] in ''JojosBizarreAdventureAbridged'' has a notable, albeit brief, one when he realizes [[TheHero Jotaro]] can out-[[spoiler:TimeStop]] him.
--> ''No... No... No, no, no, no, NO! '''MOTHERFUCKER!!! NO!! NO! NO! NO! BULLSHIT!! BULLSHIT!! BULLSHIT!!''' Okay, okay, okay. Calm down, Dio. Calm down. Calm down.''
* The EvilOverlordList refers to this a few times, most famously #24: "I will maintain a realistic assessment of my strengths and weaknesses. Even though this takes some of the fun out of the job, at least I will never utter the line "No, This Cannot Be! I AM INVINCIBLE!!!" (After that, death is usually instantaneous.)"
* ''SurvivalOfTheFittest'': [[EvilBrit Maxwell Lombardi]] has an epic one (complete with [[LaughingMad laughter]]!) in his final fight with Naoko Raidon [[spoiler:which he does not survive]].
-->"You... I have to admit, you're not the first guy on this island to seriously piss me off, but if there was a competition going on you'd of just won first fucking prize."
* Freeza in ''DragonBallAbridged'' goes through this a few times in season 2. Most notably in episode 25.
--> "Oh, I'm sorry. I'm usually far more composed. I'm just a little bit ''ABSOLUTELY LIVID''."
** He becomes even more so with Goku, not because of his resilience, but his absolute stupidity gets on his nerves.
--> Frieza: "You think you're better than me?! Lord Frieza?! *beat* WELL YOU'RE NOT! I own your planet; I own ''this'' planet! In fact - '''FUCK THIS PLANET!'''".
--> Goku: "Sorry I zoned out there for a second, what?"
** His final one is when he learns that Trunks, this mysterious warrior that showed up out of nowhere and made mincemeat out of his men, was a Super Saiyan. Enough was ''enough''.
-->'''Frieza:''' Kill. Murder! '''Destroy!''' '''''[[Series/DoctorWho EXTERMINATE! EXTERMINATE!]]'''''
* In ''ToBoldlyFlee'', Mechakara trembles and screams in incoherent rage when he finds out Terl tricked him into working for him.
* In ''WebVideo/TribeTwelve'' The Observer has a glorious one (complete with an incoherent roar that has the words '''SHUT THE FUCK UP!'') when [[spoiler:Firebrand prevents him from abducting Noah.]]
* From ''[[DNAKpts4tv Death Note: The Abridged Series (Kpts4tv)]]'':
-->'''Light:''' [[spoiler: L]], why?! ''[[HoYay Why did you leave me?!]] Why did you leave me [[SurroundedByIdiots alone with these IDIOTS!]]'' *sobbing* [[AngstWhatAngst And... yeah, I'm over it now.]]

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