* In the ''Madoka Magica'' spinoff ''Manga/PuellaMagiOrikoMagica'', the titular character, (while more of an "AntiHero") goes through this upon losing her only ally and realizing she's up against four other magical girls. And her powers aren't exactly geared towards offense.
* Marluxia has one in the manga adaptation of ''VideoGame/KingdomHeartsChainOfMemories''.
* The last episode of the 2003 ''Anime/AstroBoy'' series could have easily been renamed from "The Final Showdown" to "Dr. Tenma's Breakdown." [[spoiler: It begins in "Astro Reborn" with Tenma erasing Astro's memories to live out an idyllic life together as father and son. When that fails, and after going crazy on a pipe organ a la Phantom of the Opera, he takes over the Ministry of Science and demands one last meeting with "Tobio". When his WeCanRuleTogether speech to Astro then fails, he [[DriventoSuicide tries to commit suicide by destroying both himself and his old laboratory.]]]]
* ''Anime/MazingerZ'': Dr. Hell had several breakdowns: The first of them happened in episode ''3'', right after Mazinger-Z defeated his first [[{{Robeast}} Mechanical Beasts]], and he realized Juzo Kabuto still could surpass him and thwart his lifelong plans even after death. He destroyed all Mykene HumongousMecha he had found, declaring them being uselesss, and he very nearly gave up right then, but TheDragon Baron Ashura convinced him to not forfeit his wolrd-domination dream. Another memorable one happened in episode 68, when finally he saw himself unable to triumph over Kouji Kabuto. He destroyed all of his newest Beasts, and swallowing his pride, asked help to [[DragonWithAnAgenda Archduke Gorgon]].
** ''Anime/GreatMazinger'': Great Marshall Of Hell -TheDragon of the second season- also had several of them at the end of series, mainly in the GosakuOta manga continuity. His expression and subsequent fit when [[spoiler:Venus-A shot the flying fortress Mykeros down]] was particularly beautiful.
* Zofis in ''ZatchBell'' suffers a really nasty one. Even after he gets his ass handed to him he remains defiant and tries to keep Koko's memories of her atrocities intact. Then Brago steps in and confronts Zofis with the fact that Zofis has been afraid of him from the beginning. He then threatens to hunt Zofis down and make his life miserable even after he returns to the mamodo world unless he erases the memories. At this point Zofis BREAKS DOWN CRYING WHILE LAUGHING INSANELY AT THE SAME TIME before finally yielding.
* Tomoe has an absolutely ''huge'' freakout in ''{{Mai-Otome}}'' when she realizes that everyone (including her Valkyrie team) has deserted her for the side of the Garderobe Alliance, and Shizuru [[WasItAllALie gives her the what-for about trying to manipulate everyone she comes across]]. Even in the end, Tomoe still tries to paint herself as a victim, saying that it's ''their'' fault for not cooperating with her.
* ''DragonBallZ'':
** Vegeta, in the moment that leads to his BeamOWar, where he freaks out after he realizes that Goku has succeeded in making him bleed. [[BloodUpgrade He gets a little blood trickle from his mouth]], [[MinorInjuryOverreaction and suddenly he decides that he wants to destroy the planet.]]
** Captain Ginyu has an even BIGGER freakout when ''he'' reads Goku's Power Level. So much that, at least in the dub, Goku says to Jeice, "I think your friend's having a nervous breakdown!"
** You know what? Frieza and Cell, upon seeing their opponents' new transformations. Frieza especially. He goes from using a very polite form of Japanese (shown in translation by not using contractions) and treating the whole thing like a workout, to using a rougher speech form (contractions now in subtitles!) and attempting to ''destroy the whole planet''. Considering Frieza had nearly wiped out the Saiyan race and made the few survivors into (supposedly) loyal underlings specifically to prevent any possibility of a Super Saiyan ever showing up, because it was thought that only a Super Saiyan would be able to beat him, when Goku magically transforms into the dreaded instrument of prophecy... yeah, that would necessitate a Villainous Breakdown.
*** Later shown even quicker when Frieza shows up to get his revenge on Earth. Goku is MIA, and Trunks shows up instead. Frieza, not knowing who Trunks is, goes on long winded posturing about the backwater weakness of Earth and laughs at him thinking he can win... and when Trunks turns into a Super Saiyan, Frieza goes from gloating to ''absolutely terrified'' to completely enraged in seconds, going from standing around talking to frantically trying to blow him up.
--->'''Frieza, looking with horror as Trunks goes [=SSJ=]:''' It's- It's ''those eyes!''
*** The episode in which Cell has his Villainous Breakdown was actually called "Cell's Mighty Breakdown" in English. In summary, after Gohan delivers two punches that make him drop to his knees, Cell decides to blow up the planet; only for Gohan to to fire an even bigger Kamehameha that almost reduces to him to nothing. This results in a ClippedWingAngel that is easily beaten back to Semi-perfect form in one hit. From there, Cell decides to do suicidal bombing in order to win the fight, becoming completely unstable at this point.
*** When Cell returns as Super Perfect Cell you can tell he was going insane from being humiliated by [=SSJ2=] Gohan. He was yelling nonsense, and had facial tics that only a demented madman would have. When he finally dies at the hands of Gohan, he can do nothing but scream "'''I AM PERFECTIOOOOOOOOONNNNN!!!'''"
-----> '''Cell''': ([[EvilLaugh laughs manically]]) '''YES'''! I CAN FEEL YOU '''''SLIPPING'''''!!!
**** A much earlier breakdown contained an infamous shot of him screaming with his mouth wide open, which eventually became the infamous Lazer image.
** Vegeta's former partner Nappa really loses it when Goku, a mere "third-class" Saiyan, starts curbstomping him.
** After Majin Buu realizes he's been trapped in another dimension with no means of escape, he goes into a breakdown that results in ''a hole being ripped between dimensions from his screaming'', allowing him to escape. A later breakdown occurs in the anime when he gets his ass kicked by Vegetto after gaining a stronger form: This time his screaming ''threatens to collapse the wall between dimensions entirely''.
* Light Yagami of ''Manga/DeathNote'' lost his cool from time to time, especially [[spoiler:right at the end, when he realized he'd finally run out of plans]]. The manga is especially an excellent example, as [[spoiler:the would-be god realizes that he, whose pedestal was forged with so many deaths, does not himself want to die, and begs desperately for his life]].
** Parodied in [[http://atashi.animeblogger.net/2007/06/death-note-swimming-lessons-the-anime/ this]] blog entry, which was also made into an animated gif and [[http://www.youtube.com/watch?v=-smJ9bBEhj0 video]].
** He also gets a smaller one in episode 9, when L meets him at university and tells him, "I'm L." He manages to stay calm until getting home, where he screams in anger about how L got him, eventually giving his first psychotic laugh of the series.
** There's also the deleted scene in the anime where Light stays in the graveyard [[spoiler:after L's funeral]], and remains composed until everyone leaves, whereupon he starts laughing madly, proceeds to crawl on top of [[spoiler:his rival's]] grave and shouts, "[[spoiler: What do you think of that, L?]] This is my perfect victory! That's right—'''''I win!'''''" with a [[SlasherSmile crazed look]] on his face.
** It really began in the very second episode when L first outfoxed him with a broadcast from a fake L. L on the other hand is [[http://www.youtube.com/watch?v=eSMtT5rQeQU rarely ever fazed]].
** [[spoiler:Teru Mikami]] suffered one of these too. In the anime version, [[spoiler:he committed an extremely painful looking suicide.]] The manga version was lower-key, but still present: [[spoiler: upon realizing who Light truly is, he stares at him with the most distraught look and proclaims "you're not God!" He later commits suicide in prison out of despair.]]
*** [[spoiler: Kyosuke Higuchi. Particularly in episode 23.]]
* Lelouch from ''Anime/CodeGeass'' degenerates into anger rather quickly during those few times when he is tactically outmaneuvered (typically when the white Knightmare shows up unexpectedly), in stark contrast to his usual smug and self-confident behavior.
** When he discovers the identity of the Lancelot pilot. Lelouch was in position to terminate him at the time, but ordered a retreat when he was torn about what to do.
** His reaction to the [[spoiler:Euphinator incident]]. Once he gets back to somewhere private he ends up sitting around ''crying'' about the fact that [[spoiler:he accidentally made his second-favorite sister commit genocide, had to shoot her to stop the rampage, and then ''turned it to his political advantage''.]]
** The above instances could alternatively be HeroicBSOD 's depending on your interpretation of Lelouch.
** Jeremiah Gottwald started this after he was stripped of his rank in the wake of the supposed "Orange-kun" incident. At the Battle of Narita he nearly lets himself get killed while trying to kill Zero, and is seen after the battle gibbering crazily and fainting in the middle of a road.
** Rolo goes through this in Episode 4 of R2. After Lelouch [[TakingTheBullet takes a bullet meant for his Knightmare]], Rolo inadvertently joins the Black Knights, despite knowing his brother is Zero. Therefore, he can't capture C.C., which was his mission from the start. Lelouch plays the part of loving him as a brother in order to get Rolo on his side.
* Gackto in ''MermaidMelodyPichiPichiPitch'' starts to crack at the end of the first arc with [[spoiler:Sara's betrayal and Kaito's rejection]]. He gets better pretty quickly. Michel is less lucky, going through a series of {{Freak Out}}s and Villainous Breakdowns near the end of his arc that involve [[spoiler:killing his own servants, three for no reason, ''eating'' two of them and being appalled afterwards, being forced to possess an IllGirl, [[TomatoInTheMirror discovering he's a clone]] and, when he finally says "forget this" and [[HeelFaceTurn goes to join the good guys]], [[VillainOverride having his free will taken away]].]] Most of this is caused by the medication he's been given, which is slowly driving him insane.
* Ukyo from ''SamuraiSeven'' maintains his MagnificentBastard demeanor right up until he's attacked by Kikuchiyo in the last episode, upon which he ''snaps''.
* Dilandau in ''VisionOfEscaflowne'' wavers between this and just being outright AxCrazy. In his first few appearances, he's merely sadistic. Once Van scarred his pretty face, he moved up to outright screaming psycho killer. Near the end, after Van killed his entire squad, he starts hallucinating and babbling and only snaps out of it long enough to slaughter a bunch of people.
* Brooklyn the invincible world champion from ''{{Beyblade}}'', after [[spoiler:he was defeated by Kai who at the time was considered the biggest loser in the entire series. Not only that, but Brooklyn took the mental breakdown to the logical extreme: he convinced himself [[TheBattleDidntCount his defeat never happened]], that everything was nothing but a nightmare, a bad dream that would end soon.]]
* One of the most [[TearJerker heartbreaking]] examples comes from ''RurouniKenshin'', [[spoiler:with [[TheDragon Soujiro]] [[StepfordSmiler Seta]] revealing his horrific BackStory to Kenshin as they fight, and quickly losing it afterward.]]
-->[[spoiler:'''Soujiro:''']] You say you strive to protect those who need your help? ''WHERE THE HELL WERE YOU WHEN '''I''' NEEDED YOU?''
** Just watch [[http://www.youtube.com/watch?v=cbz7Bx2y18M it.]]
** Makoto Shishio also has a breakdown after being hit with Kenshin's ultimate technique, though this is due in part to his badly burned body going over its 15 minutes limit of fighting, causing him to lose what little sanity he has.
** [[spoiler:Enishi Yukishiro]] also has a breakdown of epic proportions at the end of ''Jinchuu'' arc. When [[spoiler:the image of his dead older sister Tomoe doesn't smile for him anymore]], during his second fight with [[spoiler:Kenshin]]... oh boooooooy, he loses it.
* ''Anime/YuGiOh5Ds'', in which TheRival, Jack Atlas, turns into a revenge-fueled lunatic upon finding out he technically lost to protagonist Yusei. Interestingly, BigBad Godwin appears to be egging this breakdown on.
** More recently, [[spoiler: Placido more or less loses it when he realizes that Yusei has a chance of beating him]], and went OneWingedAngel by [[spoiler:revealing himself to be a cyborg and fusing himself with his D-Wheel to become a sort of motorcycle-centaur]].
** Later on, [[spoiler: Aporia gets one during his fight against Jack, Rua, and Ruka. At first, he starts out as cool, calm, and in control, and spared Jack and Ruka just to piss Rua off. Later, when Rua intercepts an attack towards Jack, Aporia gets slightly pissed and attacks him, even if he could defeat one of the others. When [[EleventhHourRanger Rua acquires his own Signer Dragon]], Aporia becomes visibly angry, and moreso when Ruka destroys his Field Spell. He gets pushed over the edge when Jack destroys most of his Spells and Traps, and has a SlasherSmile when boosting his monster's ATK to 8300. He gets easily beat, falls to his death, and gets better.]]
** Yubel has a similar breakdown in ''Anime/YuGiOhGX''; after Judai finally gets it through her head that he doesn't share her twisted view of love, and is ready to commit to an HeroicSacrifice to take her down, the normally-cool Duel Monster goes psycho and decides she ''won't'' omit herself and Judai from TheEndOfTheWorldAsWeKnowIt, after all.
** Panik from the original ''Anime/YuGiOh'' suffers a huge one. At the beginning, he delights in putting Yugi through the same torture as Mai and countless other duelists, but at the end, he's reduced to a screaming, raving wreck as Yugi proceeds to push as many of Panik's buttons as he possibly can.
** Kaiba himself suffers this whenever he loses or is on the verge of losing to Yugi. He even considers blowing up Alcatraz Island before the Battle City Tournament is up after he loses!
--> '''Kaiba *before Yugi commands Dark Paladin to attack*''': '''YUGI!!! I WILL NOT BE DEFEATED''' '''''AT MY OWN TOURNAMENT!!!!'''''
** Bandit Keith suffers one when Joey defeats him in the Duelist Kingdom arc, even with Keith cheating twice over (stealing Joey's entry card before the duel in an attempt to get him disqualified and cards hidden in his wristband during the duel). He screams that the duel didn't count by virtue of Joey not using his own entry card [[INeverSaidItWasPoison (revealing his machinations in the process)]] beats up Pegasus's guards when they try to drag him away, and pulls a gun on Pegasus himself [[{{Bowdlerize}} (in Japan at least)]], demanding his prize money. He's tossed into the ocean for his trouble.
--> '''Keith''': NOBODY BEATS BANDIT KEITH! NOBODYYYYYYY!!!!
* Team Kenya leader Victor of ''{{Medabots}}'' tournament arc managed to pull of TheStoic to an admirable degree, never once shifting from his slightly angry looking frown for the whole season. He continues this throughout the whole of the final, calmly and ruthlessly sacrificing his teammates and outright destroying two of Team Japan's Medabots without once raising his voice... right up to the point where TheHero expresses his intention to keep fighting despite having lost weapons, mobility and all of his armour. Then Victor laughs. [[EvilLaugh Joker style]]. Along with his [[TheVoiceless previously silent Medabot]], who unleashes the hero's signature FinishingMove amid vitriolic ranting about the heroes [[IdiotHero abject]] [[SuicidalOverconfidence stupidity]] from the SlasherSmile sporting Victor. As one of the heroes notes, "Woah."
** That is '''nothing''' when compared to [[http://www.youtube.com/watch?v=fk6-bzv1-aY#t=135s The Japanese version.]]
** He gets worse when it is revealed that [[spoiler:the entire tournament was merely a facade for the Rubber-Robo's real plan of triggering the [[RobotWar Ten Days of Darkness]] again - the very Ten Days of Darkness that happened during Victor's childhood.]]
* [[spoiler:Takano's]] breakdown at the end of ''HigurashiNoNakuKoroNi''. [[spoiler:She loses it as the rest of the Yamainu are getting defeated by and surrendering to the protagonists and their friends and afterwards turn themselves in as they are placed under arrest. She refuses to give in, even when Okonogi eventually decides to accept defeat as well, and that's when she finally realizes that [[ManipulativeBastard No]][[KarmaHoudini mura]] tricked her into helping her just to close up a company. Upon doing so, she snaps and starts running for the hills until she trips and falls. Just as it starts raining, she starts crying and tries to commit suicide by scratching out her own throat like some other characters did in previous arcs, just as the protagonists corner her. The group sees that she's been infected with the Hinamizawa Syndrome, and she attempts to shoot Hanyuu but Hanyuu easily dodges her bullet (since she is a god, after all). Just as Takano is about to be arrested, Tomitake stops the arrest and pities her for being a victim of the Hinamizawa Syndrome, and the group decides to cure her of the disease, having her sent to the hospital for curing. After the credits roll, things calm down a lot more for her when Frederica Bernkastel gives her a HappyEnding by preventing the deaths of her parents in order to change her destiny]]. This is a rather surprising and fitting fate for her.
** And another one in ''Higurashi Kira'' Episode 2 during a battle with Oyashiro Rika and Trap Satoko alongside Ritual Tool Devil Nail Ripper. [[spoiler:Takano]] becomes furious after Satoko transforms and helps Rika back up after which the two take her and Nail Ripper on together. The girls overpower Nail Ripper and Satoko creates a pitfall trap underneath its foot that it falls into, causing Takano to FreakOut and afterwards receive an OhCrap moment upon seeing the girls about to unleash their 07th Explosion attack which destroys Nail Ripper and sends [[spoiler:Takano]] flying into the horizon, screaming "Sorry, Brother!" along the way before becoming ATwinkleInTheSky.
* Kohane's mother in ''Manga/{{xxxHoLic}}'' has one that starts just after she suspects her daughter's medium abilities are fading. This culminates in a truly epic scene where she snaps, attacks Kohane, and then proceeds to beat Watanuki senseless for daring to intervene. All of this on ''live television''.
** In ''Manga/{{xxxHoLIC}}: A Midsummer Night's Dream'', this happens to the dude who collects collectors when Yuuko walks towards him and is unfazed by anything he throws at her to keep her away. As she picks up the pace and begins to run, he gets even more desperate.
* In TheNineties ''Anime/SailorMoon'' anime.
** In Sailor Moon R, En had one of these in Episode 59 when [[spoiler: Ail told her that Mamoru never really loved her. In response, she literally ''smacks'' him aside and begins blasting the two with energy, even blasting Moonlight Knight when he intervenes]].
** Koan (Catsy) [[spoiler: goes on a blind, screaming rage after Rubeus confesses that he never loved her and her attempt at suicide with a time bomb was thwarted by the Sailor Scouts]].
** Berthier's (Berty or Birdy, depending on dub or sub) VillainousBreakdown is more depressing. [[spoiler: After Petz (Prizma) and Calavaras (Avery) refuse to help Berthier catch the Sailor Senshi, Berthier [[TranquilFury chuckles and tells everyone how she's not surprised that her sisters would abandon her and thinks it's very funny]]--until the last, lingering thread of her emotional restraint breaks and she [[DrivenToSuicide uses her Dark Water power to freeze herself and everyone around her]]]]
** Rubeus himself had one of these, starting off when Sailor Moon and Chibi-Usa caused his ship to explode, and culminating when Esmeraude left him to die on said spaceship, ignoring his pleas for help. He goes from EvilGloating to anger to begging over several minutes. And yes, [[KickTheSonofABitch he deserved it]]. It's even more noticible in the original Japanese.
-->'''Rubeus''': ESMERAUDE! Help me! ''ESMERAUDE''! (the ship blows up, killing him)
** In ''S'' season, Eudial had one when [[spoiler: the Holy Grail was revealed, flamethrowering the entire place with a deranged grin and laughing most of the way to get the Holy Grail. When Sailor Moon sends her out the window, she's really pissed, which leads directly to her death]].
** Queen Nehellenia, the BigBad of Super S has one after [[spoiler:being blasted by Sailor Moon's Golden Crystal causing her to turn into a hideous old woman and choosing to reactivate her magic mirror prison seal, rather than losing her beauty. Consequently, when she is released from the seal during the beginning of the next season she spends most of her time in this state raving about how she will make Sailor Moon and her friends suffer.]]
* [[ThePrinceOfTennis "WE... WE WERE SUPPOSED TO WIN 5-0! AND YOU RUINED EVERYTHING!"]]
* In the final of ''Anime/{{Witchblade}}'' anime [[spoiler:Wadou]] slips into complete drooling insanity when his shady enterprises bring more disastrous effects than he could imagine. Looks like [[ChronicBackstabbingDisorder little backstabbing]] is one thing, but possibility of being obviously guilty in flattening half a city or so...
* [[GenderBender Berg Katse]] in ''Anime/ScienceNinjaTeamGatchaman'' spent his/her whole life being manipulated by BigBad Sosai X, whom s/he worked his/her ass off to please. In the finale, however, [[spoiler:X revealed that he intended to destroy the world and leave Katse behind to die with everyone else. Realizing s/he'd been played for a fool his/her whole life, Katse absolutely ''lost it'' in front of the Science Ninja Team and committed suicide by throwing himself/herself into the lava pit screaming "DIE, DIE, EVERYBODY DIE!!!"]].
* Rau Le Creuset, the BigBad of ''Anime/MobileSuitGundamSEED'' spent most of the series portrayed as a very calm and calculating individual. However near the end of the series [[spoiler:when he comes face to face with TheProtagonist Kira Yamato and longtime rival Mu La Flaga, he reveals his true nature as a raving StrawNihilist and OmnicidalManiac. He then proceeds to spend the final episodes of the series screaming and ranting about how HumansAreTheRealMonsters and that everything must be destroyed until Kira finally shuts him up with a beam saber through the cockpit.]]
** [[spoiler:Azrael]]'s ''horrendous'' one in the second-to-last episode. [[spoiler:He had Natarle, Flay and the BridgeBunnies ''at gunpoint'' to make sure they'd follow his orders while screaming like a maniac, beat up Flay when she tried to rebel, shot Natarle ''four'' times after she managed to get her subordinates away from him, and ultimately destroyed Fllaga's Gundam and killed him. It's almost a ''relief'' when Murrue uses the beam cannon of the Archangel to obliterate the Dominion.]] He gives a desperate "I always win". Natarle then tell him "you lose".
** [[spoiler: [[{{Tykebomb}} Cortho Bauer]]]] too. He goes from the most reasonable of the Extended Trio, to a LaughingMad EmptyShell following [[spoiler: Shani and Orga's deaths]].
*** While Flay is more sympathetic, she has a rather tragic one in episode 28. By this point she has genuinely fallen in love with Kira despite her original plan, and as such has become even more confused than she was earlier. When she suspects Kira of pitying her she completely looses her composure, and breaks down sobbing while asking how he can possible pity someone like her (implying that she is filled with self-loathing).
** The side-story ''Manga/MobileSuitGundamSEEDAstray'' has Rondo Ghina Sahaku suffering one after Lowe Guele defeats him, despite the Red Frame losing the Gerbera Straight. It's especially shown when Ghina tries to shoot him in the back and is blocked by the Gerbera Straight's broken blade randomly floating by. Thankfully, Gai Murakumo puts Ghina out of his misery.
* The sequel, ''Anime/MobileSuitGundamSEEDDestiny'' has a major one in [[AntiVillain Rey]] [[TheDragon Za]] [[TheLastDance Burrel]]. Having been defeated by Kira, and unable to avenge Rau, Rey comes to the realisation that he and [[DarkMessiah Chairman]] [[ParentalSubstitute Durandal]] have been in the wrong. This culminates in him [[spoiler: shooting Durandal]] and going out crying for his mother.
* In ''Anime/MobileSuitGundamWingEndlessWaltz'', [[BigBad Dekim Barton]] has an epic one when his entire plan unravels.
** In the ''Anime/MobileSuitGundamWing'' anime, the Treize Faction and the colonies have become White Fang and revolt against Tsubarov, and when his mobile dolls and Lunar Base are being destroyed by Wufei, he begins ranting about how "he is invincible" shortly before [[spoiler: one of the explosions kills him]].
* ''Manga/FullmetalAlchemist'' is no stranger to this trope.
** Envy somewhats goes through this [[spoiler:whenever some forces him to go into his true form, a small fetus-like lizard]].
*** Envy's worst breakdown is [[spoiler:when Ed, holding Envy's weakened form, reveals he knows what the source of Envy's hatred for humanity is: He envied their ability to care for one another. Enraged at having his motives perceived by a human he despised above all others, Envy tears out his own Philosopher's Stone and crushes it to spite Ed's mercy]].
** [[BadBoss Central Command]], with each General more or less losing it due to [[spoiler:Roy and Olivier Armstrong's revolution defeating their forces and [[BigBad Father]] betraying them]].
** The BigBad himself, Father, [[spoiler:after ''succeeding'' at becoming a PhysicalGod, rudely had 50 million bound souls torn out of his body by Hohenheim. The imbalance was enough that [[PowerIncontinence Father could barely restrain the powere he had stolen]]. As he was forced to expend even more souls in an attempt to protect himself, his self-control decayed further until, at the end, he was a muttering, shambling hulk]].
*** But Father's ''true'' breakdown [[spoiler:occurs after his death; after confronting Truth and learning that he's no better then the humans he belittled, he's [[DraggedOffToHell dragged into the Gate]], asking in tearful screams what he should have done differently.]]
** One of the less noticeable breakdowns happens to [[spoiler: Wrath towards the end of his fight with Scar, After Scar has revealed that he has a reconstruction circle along with his destruction one, Bradley loses it and starts roaring at Scar about his use of alchemy despite it being abhorrent to the Ishvalans]]
** [[Anime/FullmetalAlchemist In the anime]], Envy nearly breaks down after [[spoiler:Dante sends Hohenheim of Light through the gate (thinking she killed him)]] but is talked into calming down when [[spoiler:Dante promises to let him kill the Elrics]]. Even after [[spoiler:killing Ed]], he isn't satisfied. Upon [[spoiler:being sent to the gate (thanks to Al using the stone and him trying to prevent it) and learning that Ed's father is still alive, he practically forces his way into the gate and loses it while transforming into a dragon in the process]].
** Also Dietlinde Eckhart, the main baddie from the movie for the first anime, near end of the climax goes into a tirade about how Ed's world is full of monsters when Ed gains the advantage. Ironically, [[spoiler:she ends up turned into something of a monster on the the trip back to her world through the gate and shot as result of her appearance]].
* Popo from ''Anime/{{Kaiba}}'' begins to lose it just as he wins. First, his mother's memory chip accidentally slips from his fingers and is destroyed, then he finds out his accomplice Cheki has had her personality wiped clean to become an obedient servant. Having lost these things precious to him and seeing the giant memory/PlanetEater plant coming towards planet Lala, he decides that letting it eat the world and achieving {{Instrumentality}} is the only solution.
* "''[[Anime/{{Madlax}} Margaret! What's happened to you?!]]'' '''''[[ThisIsForEmphasisBitch You BITCH!]]'''''"
* Creed from ''Manga/BlackCat'' has one of these for. When Train goes to Creed's SupervillainLair, pops in, saves [[DamselInDistress Rinslet]], then runs off leaving everyone confused, Creed doesn't take it very well.
* Isshiki gets one in ''{{RahXephon}}''. After spending the entire show trying to play the MagnificentBastard to prove that he isn't worthless he finally gets into a position where he can strike a definitive blow against the Mu... only to have it backfire spectacularly, leading directly to him losing his position and the OmniscientCouncilOfVagueness that he was working for denying ever having heard his name. He...doesn't take it well.
* At the end of the first arc of ''Anime/DigimonAdventure02'', the Digimon Emperor starts having one of these as a result of trying to control Chimeramon. When he's finally defeated and learns the Digital World ''isn't'' some video game to win, he finally goes WhatHaveIDone and turns back into his true identity, Ken Ichijouji. Think they're done there? It goes FromBadToWorse -- minutes later, [[DeadSidekick his partner Wormmon dies]]; when he goes back to the real world, he goes into a HeroicBSOD for two episodes.
** Ken's breakdown is even more awful in the Japanese and uncut German version where most of the things he does after Chimeramon is yell a lot and whip Wormmon while it tries to explain the situation.
* {{Trigun}} [[spoiler: completely reversed this during the climactic showdown between Vash and Legato. There, ''Vash...'' the ''good guy'' was in a mad panic, while Legato... the ''bad guy'' was remaining calm and reserved.]]
** Played straight in the manga with [[spoiler: Rai-Dei the Blade and Leonoff the Puppet Master]] For the former, Vash manages to defeat him, the guy completely loses it and tries to kill Vash with one final attack [[spoiler: only to be shot dead by Wolfwood]]. For the latter, even after he tries mindscrewing with Vash, Vash just calmly attempts to talk with him and starts reminding him of things from his past, revealing that he used to know [[spoiler: Leonoff]] when he was younger. [[spoiler: Leonoff]] can't take all these returning memories which he's apparently tried to dispose of before, and ultimately winds up killing himself.
* During the first arc of ''Anime/DigimonTamers'', Yamaki has a long and escalating sequence of these, starting with angry rants when particularly stubborn "Wild Ones" resist deletion up to a full-on, possibly partially insane breakdown when the Juggernaut program doesn't work as planned, including choking a kid and stumbling off yelling angrily to himself in proud Lovecraftian fashion. Surprisingly, he does ''not'' have one when he's [[spoiler:fired after Hypnos collapses, instead beginning a HeelFaceTurn that results in him becoming a staunch (and largely sane) ally.]]
* [[BigBad Lucemon]] from ''Anime/DigimonFrontier'' generally shows no emotion except [[SmugSnake cold disdain]]--but he loses it on the two occasions he's outmatched by Susannoomon. The second time is particularly extreme, as he's reduced to screaming about his "utopia."
* [[Anime/DigimonSavers Kurata]] has a major one during the last phase of his final battle against the heroes. First of all, his head emerges from Belphemon's chest [[SayMyName screaming the name of the Damon family]], and goes from SmugSnake to [[UnstoppableRage angrily throwing temper tantrums]] and [[LaughingMad laughing uncontrollably]] at the same time, voicing his hatred towards Marcus and his father Spencer, and goes so far as to have his OneWingedAngel form consume several Space-Oscillation devices and go on a rampage to make several rage-filled attempts to destroy his enemies. But the greatest moment of his whole breakdown occurs when [=ShineGreymon=] enters [[SuperMode Burst Mode]] and gives both him and Belphemon a CurbstompBattle. He then goes from going on his rage-filled rampage to [[DirtyCoward frantically begging for his life]]. It even continues after his final plan backfires, having him screaming for help as [[spoiler:the rift between the worlds opens and vaporizes him]].
* ''Manga/{{Naruto}}'':
** Gaara, whose sand provided him with such perfect protection that he'd never been hit, much less felt physical pain (up to a certain point, though), is stabbed in the shoulder by Sasuke. Gaara wonders what that warm, wet stuff is and then goes ''[[ChewingTheScenery nuts]]'' when he [[MinorInjuryOverreaction realizes it's his own blood]].\\
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He has an even bigger one during his final battle with Naruto later that day. For all his life Gaara's been driven by his hatred and rage, and in the final decisive clash, Naruto's love for his friends gave him the power to overcome Gaara. Realizing that his entire philosophy was wrong makes Gaara lose it completely, screaming while Naruto continues to crawl towards him. Despite this, it's Naruto's understanding of his history that helps him let go of his hate at last.
** Itachi has a rather frightening one during his fight with [[spoiler:Sasuke]]. When he finally reveals his reason for [[spoiler:sparing Sasuke]], he flips out into a maniacal, almost psychotic scream session, sharply contrasting his usual stoic behavior. Itachi implied afterwards that this was not a breakdown, ''it's how he truly is on the inside''. It's later revealed, however, that [[spoiler:the entire breakdown was purely an act.]]
** Sasuke himself cracks [[spoiler:during his fight with Kakashi after meeting Team Seven again. He gets uncharacteristically mad at a "low-life" like Kakashi merely possessing a Sharingan,]] then claims that the laughter of the villagers in his memories is ridicule because they're ignorant of [[spoiler:Itachi's sacrifice]]: he'll shut them up by killing everyone in Konoha. He goes completely LaughingMad (see it [[http://www.youtube.com/watch?v=35adqIEBj9Y here]]).
** Deidara gets pretty unhinged when he realizes that Itachi's Sharingan is more artful than his bombs, and he tries to kill Sasuke by blowing himself up at the end of their battle.
** FillerVillain Fuka has one every time Naruto manages to hurt her or damage her hair.
** When Kabuto was attacked in Part I we see his eyes go bloodshot as he reveals a bloodthirsty side. Also, after [[spoiler: Orochimaru died]], Kabuto had an existential crisis, but he claims that the person who inspired him to continue was Naruto.\\
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During Kabuto's fight with Sasuke [[spoiler:and Itachi]] Kabuto has some more of these. Confident in his beliefs and victory, he begins to shed tears when the[[spoiler: Uchiha brothers ]]fend off his attacks, and during his counterattack tearfully declares that a genius in everything[[spoiler:, like Itachi,]] wouldn't understand his desire to find his true self: no one would stand in his way.
* Hellmaster Phibrizzo from ''{{Slayers}} NEXT''. When his plan to have Lina cast the Giga Slave and destroy the world backfires due to [[spoiler:Lina being possessed by the Lord of Nightmares]], he completely flips out, eventually screaming out "I WANNA BE DESTROYED!". His wish is granted shortly afterwards.
** Valgaav from TRY inverts this trope. At first, he's fueled by vengeance against both Lina and the Dragons, with the anger and psychosis you'd expect from such a motive, [[spoiler: but after merging with Darkstar, he reveals his new plan to remake the world [[DissonantSerenity with an eerily calm demeanor]].]]
* Almost every ''Manga/OnePiece'' BigBad has one. Kuro, Don Krieg, Arlong, Wapol, Crocodile, Eneru and Moria all have epic breakdowns while fighting Luffy.
** So far, the only major enemy that Luffy has actually defeated to NOT have a breakdown was ArrogantKungFuGuy Rob Lucci. He only had time for an OhCrap.
** Moria's breakdown came at about the same time as he used [[ClippedWingAngel Shadows Asgard]].
** [[spoiler: EliteMook Blueno]] as he fights Luffy during the Enies Lobby arc [[spoiler: Blueno had previously defeated Luffy on Water 7 along with the rest of [=CP9=], especially since Luffy couldn't at first overcome their special martial arts. When the two face off again (with Blueno by himself no less), not only does Luffy get past his strong defense, he can even keep up with him. Blueno keeps his composure through that, seeming shocked and impressed that Luffy is that good, but he's still in control. Then Luffy uses Gear Second, and the breakdown begins as he is unable even to dodge, finally ending where he tries to stand up to a strong attack. Once it hits he looks like he has a smug grin on his face from withstanding the impact...only to drop a second later, out cold.]]
*** Part of the reason he's so horrified at what Luffy is doing is because this particular [[spoiler:[=CP9=] generation is the strongest one yet and has never lost a fight. Blueno had clobbered Luffy twice and stopped the Straw Hat Pirates several times already to where he feels it's a routine.]] As he doesn't know what it's like to not [[CurbStompBattle curb stomp everyone in his way]], let alone run out of options the moment the match had begun, he momentarily loses all coherent thought. The whole squad is in such disbelief that Luffy was victorious that some of his comrades pretend it didn't happen and the others decide to accept hasty (and incorrect) conclusions of what just happened…though they're probably right on the count that [[spoiler:spending five years as a bartender]] didn't help with his fighting skills.
** While the New Fishman Pirates were never entirely sane in the first place, they go completely nuts when [[spoiler:Luffy defeats Hody]]. They start killing their own men as "sacrifices" for their hatred towards humans.
*** Hody Jones, leader of the New Fishman Pirates, undergoes a ''physical'' breakdown to go with mental one. Near the end of his fight with Luffy, Hody's face seems to degenerate, becoming less human.
** Add [[MadScientist Caesar Clown]] to that list now. Also his boss, [[BiggerBad Doflamingo]] seems to be heading this way in near future as the Straw Hats have finally got him annoyed.
*** However, the person that has driven Doflamingo closest to that point so far is not Luffy, but [[spoiler:Law. With the capture Caesar, Law made his former boss an ultimatum: resign from his position as a Warlord of the Sea and be given back Caesar, but in the process lose the protection of the World Government and be hunted down by the Admirals. That, or ''keep'' the position, not get Caesar back, be unable to provide [=SMILEs=], and in the process piss off his most important business partner, Kaido of '''''the Four Emperors''''', and assuredly get wiped out. This SadisticChoice pissed Doflamingo off so much that he went into an UnstoppableRage, started slaughtering the marines of G-5 and gave Smoker a ''severe'' NoHoldsBarredBeatdown, all while demanding the heads of the Straw Hat Pirates and Law.]]
* In ''GunXSword'', [[spoiler:the Claw's dream is delayed at the 11th hour by Ray's HeroicSacrifice, leading to his claw twitching for a full episode. When Van puts his dreams of Instrumentality down for good, he goes ''completely off the handle'']].
* This happens to Griffith in ''{{Berserk}}'' when Guts defeats him in one single stroke to earn his freedom. Guts' desertion marks a turning point in Griffith's life and ambitions and everything falls apart for Griffith from there on, making it an apt breakdown.
* Johan from ''Anime/{{Monster}}'' has three of these -- one [[spoiler:after finding a Bonaparta children's book that helped mess him up as a kid]], and the other [[spoiler:after he realizes that his memories are actually Nina's]], the latter leading to the climactic scenes in Ruhenheim. Then he has a freakout at the climax when [[spoiler: his sister determinedly interrupts his KillHimAlready-moment with Tenma to CarebearStare at him just as he's getting into his BreakingSpeech stride. "I am ''too'' irredeemable! Now shoot me in the head or the kid gets it!"]]. Given what he is, these make him even scarier.
** [[spoiler:[[TheSocialDarwinist Peter Capek]] is an even more straightforward when he discovers that [[spoiler:he and his entire underground neo-nazi movement [[OutGambitted were being manipulated all along]] by Johan, who never cared about their promises of power and has started to kill them all one by one. Capek rapidly begins to lose it, to the point of killing his chaffeur out of fear - which causes his former bodyguards to shoot him down in reprisal.]]
* Harry [=McDowell=] of the ''{{Gungrave}}'' anime is always completely calm and collected, no matter how bad a situation he's in, and never fires a weapon himself, until Brandon Heat, his best friend points a gun at him. Harry draws his own gun, fires at least five shots into him, then rams the barrel into his eye and fires a sixth. Later on he gets two other breakdowns as he's trying to deal with the fact that he killed his best friend whom he's trusted and relied on since they were children and whom he wanted to stay by his side.
** Plays out a little differently in the game's storyline. Harry just gets a punch to the face because he had plans to manipulate Maria into being Brandon's wife, something that Brandon would never do. Harry's also oddly calm when Grave/Brandon confronts him at the very end of the game. With all of Harry's lieutenants and monsters destroyed, he simply [[spoiler: accepts his defeat and allows [[GracefulLoser Grave to kill him]]]].
* The Anti-Spirals (represented by their avatar the Anti-Spiral King) of ''TengenToppaGurrenLagann'' are archetypal inhumanly calm and dispassionate ScaryDogmaticAliens. Until the last episode. During the FinalBattle the Anti-Spirals unleash ''thousands of years'' worth of repressed emotion and [[HotBlooded Hot Blood]], ranting about the sacrifices they made to protect the universe and screaming that the protagonists are idiots who don't realize that their actions will lead to the end of everything.
** It's actually a vital plot point if you look at it right. [[spoiler:Both Lord Genome and the Anti-Spiral are very calm and confident, SmugSnake levels on the part of the Anti-Spiral. When the heroes manage to fight them face to face, they go completely HotBlooded and proceed with the ass-kicking. The reason it's a plot point is because the Anti-Spirals, and by extension Lord Genome, were trying to '''suppress hot blooded badassery.''' {{Lampshaded}} on the part of Lord Genome and foreshadowed for the Anti-Spiral when Anti-Spiral Nia says "Not even Lord Genome could suppress the Spiral instinct."]]
** Cytomander also loses a fair chunk of his self-control during the Battle of Teppelin, such as cackling like a maniac after [[spoiler:Simon unleashes a drill MacrossMissileMassacre]].
* In ''FruitsBasket'', [[spoiler:Akito Sohma]] has a rather fragile grip on reality and thus it takes little to shake [[spoiler:her]] up. A first breakdown comes [[spoiler:after Kureno is freed from the curse]], causing [[spoiler:her]] to go from a scared but mostly kind child to full-on possessive and clingy, beating and locking up the other Zodiac members to keep them from "leaving" too. A second one comes towards the end of the series, [[spoiler:after Momiji is freed]], panicking [[spoiler:her]] again to the point of nearly stabbing [[spoiler:his]] mother with a knife. This breakdown is only intensified when [[spoiler:Hiro is freed]] ''in the middle of the attack'', leading [[spoiler: Akito]] to [[spoiler:stab Kureno in the back and then go off in a delirious state to attack Tohru Honda, who she blames for everything]]. However, [[spoiler: Tohru manages to actually ''get'' to Akito and talks to her kindly... and after Tohru almost falls victim to DeathByFallingOver in the middle of their [[IKnowYouAreInThereSomewhereFight confrontation]], Akito ''finally'' realizes what a fucked-up bitch she is and has a HeelFaceTurn.]].
** [[spoiler:Akito]]'s [[EvilMatriarch mother]] Ren, who is just as screwed-up, has a breakdown of her own when she learns that [[spoiler:Shigure only slept with her and showed any interest in her because he was in love with ''Akito'' and thought Akito would look more like her, had she been raised as a girl and not as a boy per Ren's selfish demands]], thus causing her to enter [[spoiler:Akito]]'s room with a knife and demand that [[spoiler:she]] hand over a box which supposedly had something of Akira ([[spoiler:Akito's late father]])'s in it. [[spoiler:It's empty.]]
* In ''Anime/DarkerThanBlack'', TheManBehindTheMan does not react well ''at all'' to [[spoiler:Hei completely wrecking TheSyndicate's Contractor-genocide plan and Kirihara recording his MotiveRant so that she can arrest and prosecute him.]] In fact, he starts ''strangling'' someone who he was asking not 5 minutes earlier to join him.
* ''Manga/{{Bleach}}''
** Ulquiorra gets a brief one in his fight with Ichigo. [[spoiler:After his first release and curbstomping Ichigo, he loses his usual composure when despite seeing the difference between their powers Ichigo refuses to give up.]]
** In chapter 385, [[spoiler:Tousen]] loses his composure and goes on a tirade explaining why [[spoiler:he chose to betray Soul Society]]. To add to the effect, [[spoiler:Tosen's blank Hollow mask ''[[http://www.mangafox.com/manga/bleach/v44/c385/13.html cracks open]]'' in a manner that resembles ''[[http://www.mangafox.com/manga/bleach/v44/c385/14.html teeth]]''.]] And in the next chapter, he goes ''completely'' ''[[DrunkWithPower insane]]'' after [[spoiler:his Resurrecion grants him eyesight. [[DeathByIrony This proves to be his undoing.]]]]
** After being hit with a second bankai from Soi Fon, Barragan Luisenbarn loses all composure and goes on a rant that covers every facet of this trope. He proclaims himself to be a god, orders his opponets to bow before his might, and keeps muttering "You insects!" over and over again. It only gets worse after he starts to evaporate, culminating in him throwing his axe at his own boss!
** Aizen spends most of his screen time being invincible, and talking about how invincible he is, while never raising his voice or getting mad. [[spoiler:Once the Deicide Arc rolls around, he's defeated everyone that's fought him, and is on his way to create the King's Key and destroy Soul Society. Then Ichigo returns, having finished his training to use the Final Getsuga Tenshou. Ichigo manhandles Aizen with nothing but his physical strength, and Aizen loses some of his composure. Aizen transforms into monstrous form after monstrous form, yelling about how much better he is than Ichigo, and losing it more and more as they fight. Once Ichigo effortlessly destroys Aizen's perfectly chanted Black Coffin Kido spell, he cracks completely, and starts ranting at length about how he's the perfect existence, and that he can't be stopped by Ichigo. Then Ichigo blasts him with his Mugetsu technique, Aizen is rejected by the Hougyouku, and Urahara Kisuke's Sealing Kido activates, sealing him in an energy tree as he screams that he's the only one with the right to change the world. He's cut off mid sentence, and is next seen being sentenced to 20,000 years of imprisonment by the Central 46, since they can't execute him because he's immortal due to the Hougyouku. It's all very satisfying, as Aizen is {{The Scrappy}} to a vast number of Bleach readers.]]
** Also Szayel Aporro Granz, who starts out smug and confident in his superiority. When Mayuri starts messing with him, however, he throws a temper tantrum and starts swearing a lot. He's also breaking down shortly before his death, begging for Mayuri to hurry up and kill him, but then again from his perspective, he's been frozen in place with a sword slowly piercing him for a MILLENNIUM by then.
** Zommari probably had the biggest one out of all the Espada, he comes off as being the most [[TheStoic composed]] of the group, going on long [[LargeHam tangents]] on how his opponent cannot beat him, believing his powers is enough to stop him from moving. When he attempts to have that man's sister to be killed, he gets tired of this game and simply casts a Kido to paralyze her. Zommari, more explict in the anime, immediately loses it and demands his target to move; immediately following a 360 attack by his enemy, causing him to use his full power while proclaiming loudly, even though it fails miserably. The Next chapter has him in MadnessMantra mode, going on a [[LargeHam speech]] about WhatMeasureIsANonHuman, ending with a clear VillainousBreakdown of him praising the BigBad as he dissolves.
** Kenpachi's clear enjoyment of what appears to Nnoitra to be a losing battle starts to strongly unnerve Nnoitra. As Kenpachi continues to laugh and enjoy himself, Nnoitra descends into raving and swearing at him. Eventually, this psychological edge causes Nnoitra to be too shaken to think to defend himself when Kenpachi finally goes for a killing strike, crippling him in one blow.
** In chapter 466, Xcution member Yukio drops his DissonantSerenity and goes completely off the handle when Hitsugaya brings up his ParentalNeglect issues.
** In chapter 477, Tsukishima, who's normally calm and composed, has a FreakOut moment following [[spoiler:Riruka shielding Ichigo and Rukia from his attack that was meant to kill them]]. He gets [[http://www.mangareader.net/bleach/477/15 this]] look on his face and screams at her to "MOVE!!!" In chapter 478, we see Tsukishima acting deeply upset over [[spoiler:Ginjou's death]] and having another FreakOut moment.
* [[spoiler:Fenrir the Princess of Disaster]] has one in ''{{Pretear}}'' when Mawata is saved by her family and Sasame ''appears'' to have second thoughts about siding with her. However, [[spoiler:considering before her FaceHeelTurn she was already [[ShrinkingViolet an insecure, needy young girl]] and [[LoveMakesYouEvil fell when Hayate rejected her love]] ]], this isn't so much a sudden change in personality as it is a revelation that [[spoiler: Takako, [[UsedToBeASweetKid the sweet girl she used to be]], is still there underneath the villain, and is not beyond salvation. Soon, [[IKnowYouAreInThereSomewhereFight Himeno succeeds into bringing Takako/Fenrir back to the side of good]].]]
* In chapter 272 of ''MahouSenseiNegima'', [[spoiler:Kurt Godel]] loses some of his composure when [[spoiler: Negi reveals that he knows that the Magical World is falling apart]]. Negi then accuses him of betraying the ideals of the people he looked up to in his youth [[spoiler: namely Arika and Nagi]]. [[spoiler: Godel]] gets pissed, calls Negi a "little boy who's too smart for his own good", and decides to ''force'' Negi to be his pawn. [[spoiler: It fails.]]
** And in chapter 298, Fate, who's normally coldly [[TheStoic Stoic]] visibly trembles with wrath and looks upset when Negi declares that he will prevent the future in which the magical world collapses from happening.
* Anime/{{FLCL}} has a strange one [[WidgetSeries (Anyone surprised?)]] when Naota reveals that he's absorbed the powers of Atomsk... it's Haruko that snaps, who immediately grabs her weapon ([[InstrumentOfMurder read: guitar]]) and lunges at Naota, screaming "THAT POWER'S MINE!!!"
* [[MagnificentBastard Yokoya]] in LiarGame could lie, deceive and bribe his way through any situation. That is, until he met [[BewareTheHonestOnes Nao]] and [[TheChessmaster Akiyama]]. At the end of the Second round, he managed to profit greatly from the game, when everyone else had just managed to pay off their debts and gained nothing. He began [[EvilGloating gloating]] to Akiyama that he had lost, when Nao of all people [[BreakingSpeech mentioned]] how Yokoya had contradicted his earlier philosophy of dominance. Instead, he had turned to tricks to profit and unknowingly had three traitors on his side. "Even though you made the big money, Mr Yokoya, you lost the game to me."
** In the Pandemic game, when he tried to bribe money to one of his teammates who trapped himself in the examination room, his teammate continually kept demanding more and more money, until Yokoya visually lost his calm demeanor and began violently kicking at the door ... only to find out that [[spoiler: it was Akiyama in the room the whole time and who he was slipping money to.]]
* It's difficult to name a ''{{Hellsing}}'' villain who ''doesn't'' have a VillainousBreakdown.
** Almost every single person who's faced down Alucard suffers such a breakdown at the end of their fight. Like Rip Van Winkle (whom you could almost feel sorry for) and Luke Valentine (if only for Alucard's PreMortemOneLiner: "I'm a dog? Then you're dog food." Followed by mastication.)
** Zorin Blitz gets seriously freaked out when she learns just why [[BewareTheNiceOnes she shouldn't have fucked with Seras]]. She was all confident while she was pulling a BreakTheCutie tactic on Seras, [[MindRape mind raping]] and maiming her, killing Pip, and referring to the dead Pip as an insect. Seras then snaps and Zorin had a permanent OhCrap expression on her face up until [[spoiler:Seras kills her by grating her face against a wall until the only intact part of her face left is an ear.]]
*** If that wasn't bad enough, [[spoiler:when it's obvious she's going to be killed, Schrödinger appears and tells her flat out that [[BigBad the Major]] won't be using the suicide chip on her because she didn't fight her enemy honorably. [[KarmicDeath As such, she would be dispatched in such a method as well.]]]]
** [[spoiler: Enrico Maxwell has one during his assault on London, it rose when Alucard summoned his familiars and massicared his armies, and it went on max level when Anderson breaks the armored glass protecting him from Alucard's familiars. This is followed by him being ImpaledWithExtremePrejudice.]]
** In fact, there are probably only three villains who avert this trope: Jan Valentine (who goes out ''laughing his ass off''), the Captain (who goes out the same way), and the Major (who just wanted constant and everlasting war, regardless of who won or lost).
* Daniel D'Arby's breakdown in Part 3 of ''Manga/JoJosBizarreAdventure''. Jotaro beats D'Arby in a game of poker by [[{{Gaslighting}} messing him up]] through sheer bluffing! D'Arby is an expert gambler, had the whole game rigged to his advantage, and Jotaro had never played poker before that moment. Jotaro's poker face was just ''that'' good.
** From Part 2, Esidisi invokes this by crying like a spoiled brat once his hand is cut off to calm himself down and unnerve Joseph. [[spoiler: He suffers a real one once Joseph manages to out gambit him, leading to a futile ClippedWingAngel in an attempt to take him with him]].
* Aureolus Izzard from LightNovel/ACertainMagicalIndex'' goes from a calm, MagnificentBastard to a murderous lunatic when Stiyl and Touma inform him that his complicated plan to [[spoiler:find and trap a vampire, then force it to turn Index into a vampire in order to save her life is completely unnecessary because Touma already saved her. He gets even more upset when Stiyl questions [[FridgeLogic why he needed to find and trap a vampire in the first place]] if he has RealityWarper powers, he could have just summoned one or even turned Index into a vampire himself. Then, he ''completely loses it '' when Touma acts like Aureolus chopping his arm off means nothing to him and slowly advances on him, laughing like a crazed lunatic and giving a TheReasonYouSuckSpeech. In a blind panic, Aureolus screams, "He's a monster!" and has just enough time to go OhCrap before his RealityWarper powers turn against him and cause a dragon to emerge from Touma's arm stump, which finishes him off.]]
** Accelerator also has one of these (not sure if other moments really count for this) after Touma slaps his hand away, something that has never happened due to his vector control ability redirecting any and all attacks or block attempts.
*** ''Manga/ACertainScientificRailgun'' shows more of the fight from Accelerator's perspective, and he is having a prolonged FreakOut during his fight with Touma due to finally realizing [[HeelRealization what kind of a monster he is]] for killing the Misaka Sisters.
** Awaki Musujime has one when Kuroko gives her a breaking speech about exactly what is wrong with her as a person, and exactly why everything is ''her'' fault, not the fault of her powers or her circumstances. She goes so crazy for a moment that she collapses the entire building on Kuroko (who barely escapes alive thanks to Touma and Misaka showing up).
* ''Manga/KatekyoHitmanReborn'': The normally calm and polite Byakuran goes apeshit following Uni's HeroicSacrifice because of her key importance in his plan to become ruler of all time and space.
** Daemon Spade loses it when [[spoiler:Tsuna gains the combined powers of the Vongola ''and'' Shimon rings]]. He becomes a screaming lunatic futilely lashing out in rage and denial. The breakdown is reflected in his appearance -- his once bishonen form becomes a warped and hideous mass BodyHorror.
* SoulEater is fond of these, since most of its characters aren't exactly stable.
** [[DarkMagicalGirl Dark Magical]]...[[AmbiguousGender Person]] Crona is constantly on the cusp of a nervous breakdown anyway, but goes absolutely ballistic when Maka connects with their psyche.
** Giriko has one following Arachne's death. And later, he follows it up with an even bigger one. In fact, he gets ''so angry'' that [[spoiler: his ''soul explodes.'']]
** Kishin Asura has these constantly in the anime, due to his overwhelming terror at anything he doesn't understand.
* Iwao Washizu from ''{{Akagi}}'' completely breaks down and briefly goes catatonic when Akagi manages to outperform him in their epic {{Mahjong}} match. Akagi personally has to talk him into continuing their game, and gives himself a disadvantage for the next round.
* [[BigBad Grings Kodai]] from ''PokemonZoroarkMasterOfIllusions'' is normally quite the SmugSnake, but when [[spoiler: Zoroark foils his plan, he does both variations, first flying into a psychaotic rage and trying to murder her and her son. When that backfires, he becomes a lot less composed than he used to be.]]
* In the second-to-last episode of ''ShamanKing'', Hao gets a huge VillainousBreakdown when Yoh regains his soul and his consciousness to the joy of his friends and his fiencee Anna - leading Hao himself to lose his cool and get really mad as well as go AxCrazy, to Opacho's upset.
--> '''Opacho''': ...I don't understand. I thought we were friends... (walks away sadly)\\
'''Hao''': Hah... hahaha... HAHAHAHAHAHAHA! Opacho's gonna miss out on all the fun! '''HEAR ME NOW, SPIRIT OF FIRE!''' (Spirit of Fire appears) '''REGENERATE, AND ARIIIIIISSSEEEE!!! Devour him!''' (Spirit of Fire lunges at the Great Spirits and starts absorbing their energy)
* In the [[Manga/TheLegendOfZelda Legend of Zelda: Four Swords manga]], Shadow Link gets one when Vio is freed by the other three Links and the Links defeat his Hinox servants. His VillainousBreakdown has him fly into a rage and hit the four Links with a ThisIsUnforgivable and make one last lash at them - only to be defeated by [[ThePowerOfFriendship the combined power of their Four Swords]].
** He later returns, reformed after his VillainousBreakdown, to make a HeroicSacrifice to destroy the Dark Mirror and therefore help the other four Links defeat Vaati.
* Moo in Anime/MonsterRancher Episode 47. During his final attack on the Searchers, he is completely overcome by the evil of his soul, and completely goes berserk, even destroying many of his own men. [[spoiler:In the next episode he is finally destroyed.]]
* ''Cyrus'' of all people has one of these in ''PokemonDiamondAndPearlAdventure'', [[spoiler:which leads to his HeelFaceTurn]].
* ''ShugoChara'': Nikaidou, [[spoiler:after capturing Su (And, previously, both of Amu's other Charas, although, by that time, they had been freed),]] seems to become more, and more unhinged, constantly ranting about his obssession with success and societal promotion, [[spoiler:although whether or not that was him trying to [[HeelFaceTurn (Thankfully, failingly.)]] "convince" him - self to not embrace his past Dreams is left un - clear.)]] and typing furiously upon his computer while once hitting his desk hard. [[spoiler: His only moments of knowingness come when Su speaks towards him, trying to convince him to let her out to clean his room and make him a new cup of coffee, rather than escape and, more noticeably, when she (Albeit inadvertently.) reminds him of his own Dreams.]] An odd case within the fact that only one protagonist [[spoiler:(Su, who is being held hostage.)]] ever gets to see most of it within action. And his face. Good God, [[NightmareFace his face.]] Also [[spoiler:becomes completely subverted during The Anime's finale/conclusion of the manga's third arc: Gozen breaks down, but it's not at all villanous: Goxen has been revealed to be Hikaru, the boy that Amu encountered [[CreepyChild (Within an, at times, ''very disturbing'' fashion.)]] before - hand, and he is crying through - out years of repressed sadness due towards his extraordinarily strict upbriging, which the return of his Heart's Egg towards him lets completely out, thus stopping his usual (albeit false) [[EmotionlessGirl extraordinarily unfeeling temperament.]]]]
* Throughout the ''Anime/CowboyBebop'' episode "Pierrot le Fou", Tongpu/Mad Pierrot is set up as a psychotic and seemingly invulnerable assassin who can stop bullets with the greatest of ease. [[spoiler:However, when Spike manages to embed a knife into the guy's thigh, the up-until-that-point cold-blooded killer is reduced to a bawling mess thrashing on the pavement and crying for his mommy. The earlier establishment that his mental state and powers are the result of genetic engineering experiments performed on him does serve to make this childish tantrum not seem so out-of-the-blue]].
* Somewhat similar to the {{Trigun}} example above, the ''protagonist'', Shinji Ikari, goes through one in ''[[Anime/NeonGenesisEvangelion The End of Evangelion]]''. Normally, it would probably just fall under GoMadFromTheRevelation... except that [[WoobieDestroyerOfWorlds Shinji's]] [[TraumaCongaLine misery]] leads him to [[SuicidalCosmicTemperTantrum take it out on]] [[KillEmAll the rest of humanity]].
* Minor character [[AlphaBitch Kashiwara]] has one in the first episode of GunBuster. After [[TheHero Noriko "Wipe Out Girl" Takaya]] is chosen for a position that she felt should have been hers, and Coach doesn't do a damn thing to explain himself, Kashiwara tricks Noriko into a mecha battle - up to this point, Noriko's nickname of "Wipe Out Girl" was given to her ''[[{{Dojikko}} for a reason]]''. As Kashiwara keeps [[CurbStompBattle kicking Noriko's ass]], she goes on a brief rant about how the latter girl has no skills or talent, and her epxression is [[NightmareFace truly frightening]]. And when Noriko turns off her monitor on a desperate gamble, then Kashiwara goes ''completely'' '''apeshit''' and evidently tries to [[AxeCrazy kill her]]. Fortunately, though, Noriko [[ShutUpHannibal responds with]] [[SingleStrokeBattle her]] legs.
* ''SakuraGari'': Sakurako, Souma's {{Yandere}} sister, suffers a massive ([[TearJerker and heartbreaking]] one near the end. [[spoiler: S/he's actually a boy named Youya, desperately lonely and unstable, and s/he ends up commiting suicide when s/he thinks s/he's killed Souma.]] But not before... [[spoiler: after having loced Souma and Masataka away in a burning building, s/he stumbles in Lord Saiki's bedroom, whispering "Father... Sakurako has always wanted to see you...", then starting to chop up everything in sight with his/her trusty katana, crying and screaming "Why was I born? Why am I here? Why do I exist, Father, WHY?!" When s/he stops and realizes that Souma might be dead, s/he screams in horror, lets go of their WeaponOfChoice and then runs under the cherry trees...]] Few later, [[spoiler: we find him/her dead, his/her wrists slit open and their lifeless body inside the pool. And Souma bawls his eyes out with his/her lifeless body in his arms.]]
* ''KarakuridoujiUltimo'': In chapter 11 Rune completely looses it, with an ultimate [[http://www.mangareader.net/770-42633-16/ultimo/chapter-11.html crazed look on his face, while bawling his eyes out at the same time.]] Then there's the fact he's perfectly willing to kill his best friend because he doesn't love him back, then commit suicide.
* ''Anime/PerfectBlue'' features both [[spoiler: Rumi]] and Me-Mania experiencing this towards the end. [[spoiler: Rumi]] ends up permanently institutionalized and delusional.
* ''Manga/WolfGuyWolfenCrest'': Kuro, multiple stages. Haguro's is pretty epic too.
** [[spoiler:Post Haguro's death, Ryuuko just lost what little bit of sanity she had left (and considering how AxCrazy she was there wasn't much left), wandering on the streets and selling her body in utter disbelief now that she lost Haguro and couldn't get Inugami.]]
* ''RosarioPlusVampire'': Kuyou in chapter 52 of manga season 2.
** And Akuha at the end of chapter 53 breaks down laughing and crying out of insane jealousy after she sees Moka with Tsukune.
* [[SadistTeacher Kanamori]] has two in the manga ''HiganbanaNoSakuYoruNi.'' The first is when Marie Moriya, the girl he's been molesting during his "supplementary lessons" with her, threatens to tell others about their ''supplementary lessons,'' he snaps, [[spoiler:and strangles her to death]]. The second breakdown was when he [[spoiler: failed the three rules about Mesomeso, and [[TheDogBitesBack Marie becomes Mesomeso, and is about to kill him]]]], he breaks down, and told her that he always loved her. She tells him she loved him too, and gives him the KissOfDeath.
* In ''TokyoMewMew'', Kish gets this when he realizes that the Mew Aqua doesn't actually make people stronger, just stores power. [[NotGoodWithRejection He gets even worse with every rejection courtesy of Ichigo]].
** And later, Deep Blue gets this when [[spoiler:Ichigo reaches out to Masaya, who apparently starts fighting back against the aliens' leader from within him. The more Masaya fights back, the more Deep Blue loses his composure. And he gets even worse when he finally realizes what is happening to him, and eventually gets held in place by Masaya much to even more of his agitation. His breakdown gets more and more intense until Ichigo becomes forced to defeat them both in order to set her beloved Masaya free]], which is a rather nice end to Deep Blue.
* The Dark Precure goes through this near the end of ''HeartcatchPrettyCure''. When she first appears, she's calm, collected and a walking can of CurbStompBattle. However, once Yuri regains her HeroicResolve and returns to action, she starts to steadily lose her composure, especially since Yuri's finally dumped her baggage and is fighting clearer. By the time of the final battle, and [[DrunkOnTheDarkSide hopped up on a power boost]], she's gone [[ScreamingWarrior completely berserk]], and all she wants to do now is just kill Yuri [[spoiler:so she can have their father, [[TheDragon Professor Sabaaku]] (a.k.a. Yuri's father Mr. Tsukikage, brainwashed by [[BigBad Dune]]), [[WellDoneSonGuy accept her as his only daughter]]. Though after she is fatally wounded by Cure Moonlight, and a now-freed Mr. Tsukikage accepts her ''and'' Yuri as his daughters, she seems to finally let go of her rage and hatred as she [[DisappearsIntoLight dies]].]]
** BigBad Dune soon follows. When we first seem him, he's a SmugSnake who gladly wipes the floor with the other Cures and turns the Earth into a desert. Once Yuri finally drops the rest of her baggage, restored to full power and her and Tsubomi are reunited with Erika and Itsuki that things start going south for Dune. When he's nearly purified by the Heartcatch Orchestra, he flips out, grows to massive proportions and ''starts punching the Earth'', declaring that nothing can defeat the hate in his heart.
* Darcia the Third from ''WolfsRain'' has several in varying degrees, but the biggest comes in the last few episodes, where he kills the main cast so *he* can be the one to open Paradise. His last moments are spent cackling madly, with his wolf form managing to look rather insane as well.
* [[SadistTeacher Koichi Shidou]] from ''Anime/HighschoolOfTheDead'' receives one when [[spoiler: [[NotWorthKilling Rei deems him unworthy of being killed.]]]]
* Chaka in ''Manga/BlackLagoon'' is an arrogant small-time Yakuza with [[SmallNameBigEgo delusions of grandeur]] who tries to make a name for himself by kidnapping Yukio, the new head of the Washimine clan. When Rock, Revy, and Ginji storm his hideout to rescue her, he reacts with his usual bravado. However, he's quickly subjected to a HumiliationConga. The cracks start to appear when Rock snatches his hostage from right under his nose, leading him to shoot his own henchmen in the back when they try to abandon him. Things get worse when he challenges Revy to a duel, only for her to dropkick him in the face and declare him NotWorthKilling. Finally, when Ginji [[spoiler: chops off his hands and knocks him into a swimming pool to drown]], he's reduced to thrashing around and shrieking impotent death threats.
* Joker of ''SmilePrettyCure'' suffers a major one. At this point, it seems like he's achieved some sort of victory, gathering tons more of negative energy to revive BigBad Pierrot. And the icing on the cake, he's created his own group of PsychoRangers, the Bad End Precure, and sends them to deal with the girls for good. Things fall apart when he realizes that the Miracle Jewel he sought was just a fluke - it was [[spoiler:just the egg form of Queen Candy]]. It goes downhill once the girls are able to overpower their twins and return to the real world that Joker flips out, revealing he's only doing this because he wants to sow chaos, that he ''has'' no real purpose. At the very end, a batch of the Bad End ink falls on top off him and he "gleefully" disappears and is absorbed into Pierrot.
* In ''Anime/GirlsUndPanzer'', when Alice finds out that Oorai has discovered that they were [[spoiler:intercepting their radio transmissions]] and is [[HoistByHisOwnPetard using that tactic against them]], she breaks down and starts ranting about various things, such as a boy who won't notice her feelings, the supposed superiority of the Sherman Tanks, and how [[spoiler:if Oorai is getting shut down, it should be shut down immediately]]. She briefly regains her composure when the team captain sends reinforcements, but when the team loses anyway, she breaks down again, especially when Kay states she wants to give her a talking-to.
* Episode 11 of ''{{Canaan}}'' has Liang Qi suffering severe SanitySlippage (not that she's ever been sane to begin with) as a result of her "nee-sama", Alphard, abandoning her. [[spoiler:When Cummings tries to get her to see reason, she shoots him in the leg and then gives him the beating of his life, all the while ranting loudly about how she will destroy anyone and anything that gets between her and her "nee-sama." Then Alphard battles her hand-to-hand, and Liang proves TooKinkyToTorture, begging for more pain from her. When Alphard's attention turns toward Canaan blasting up the soldiers raiding the base, Liang Qi loses it big-time. She breaks into Cummings's lab and takes a dose of the Ua virus in a mad bid to give herself synaesthesia like Canaan. But since Liang Qi doesn't have the genes to handle synaesthesia, she suffers horribly both physically and mentally. Then Alphard shows her the card that Liang wrote in Siam's name, revealing that she knew all about her plot to "rescue" her, and revealing that Siam never called her Alphard...but Canaan. This results in Liang Qi losing it completely, becoming so far gone that she doesn't even recognize her own reflection in the mirror, believing that it is Canaan staring back at her. It ultimately falls to Cummings to deliver a MercyKill]].
* ''CarnivalPhantasm's'' WackyRacing episode had this happen to [[FateStayNight Gilgamesh]] when he realized that Shirou and Saber were finally catching up to him, Archer, and Rin as they were nearing the finish line. The arrogant, prideful god-king immediately lost his temper big time, screaming the word "bastard" several times and calling Shirou and Saber "goddamn brutes" as the three teams of racers lined up neck and neck and approached closer to the finish line.
* [[spoiler:Adachi]] from Persona4TheAnimation immediately starts freaking out when he realises that the kids he's fighting aren't as pathetic as he expected, and also that they're rejecting his philosophy, [[spoiler:he almost kills himself too, but then he gets possessed by Ameno-Sagiri]]
* ''Manga/AttackOnTitan'' plays this for drama, showing just how terrifying a broken villain at the end of their rope really is.
** When confronted and exposed as [[spoiler: the Female Titan, Annie's]] calm shatters and the body count rapidly begins to rise. Unlike in the previous confrontation, [[spoiler: Annie]] is clearly desperate and begins to flash back to their FreudianExcuse while delivering a vicious beatdown to Eren. [[spoiler: Rather than attempt to capture him, however, she makes a final desperate attempt to escape by {{Wall Crawl}}ing up Wall Sina. When this fails, she begins to weep and seals herself away in a CrystalPrison]]. The battle leaves the city in ruins, with many wounded or dead among the military and civilians alike.
** After TheReveal, [[spoiler: Reiner]] was already suffering from SanitySlippage but made no effort to attack the heroes. This changes completely once [[spoiler: Erwin manages to rescue Eren, seriously wounding Bertolt in the process]]. Cue the [[spoiler: Armored Titan picking up and ''hurling'' other Titans at the fleeing soldiers with ImprobableAimingSkills, cutting off their escape. Mikasa and Jean]] are both injured, while many soldiers are killed in the ensuing slaughter. Armin is horrified by the enemy's sudden reckless behavior, wondering if he even ''cares'' anymore if Eren ends up being eaten along with everyone else. [[spoiler: Without Eren's EleventhHourSuperPower, everyone would have ended up being devoured]].
* In episode six of ''Anime/TenchiMuyo'', it seems that Kagato is close to victory: Tenchi and Ryoko are helpless, Ayeka and Mihoshi are trapped in another dimension with Washu and the Juraian ship Tsunami is being drawn into the Souja with the namesake Goddess and Sasami being dragged in for the ride. Then, Tenchi decides to follow up on some advice Tsunami gave and, when Kagato attacks Tenchi again, he's stunned to see him with three Light Hawk Wings. He's quick to point out that there's no way Tsunami could be giving him her power until he realizes the true horror: this isn't Tsunami's doing.
-->'''Kagato:''' It's '''''YOU!''''' You're doing this!
* Two examples from the original ''VideoGame/{{Strider}}'' manga:
** The Enterprise scientist in Chapter 3 starts out very confident in the security he has got for his secret lab, as he tells Faceas Clay through a phone call. This confidence vanishes just as Hiryu and Cain make quick work of his men, making him jump on the phone to ask for reinforcements moments before both striders confront him. But the real breaking point comes right after Hiryu destroys the Zain Terminal, which he treated as his child: he goes LaughingMad, mocking Hiryu and Cain that their efforts are futile since the terminal they destroyed was but one of millons and finally burns to death while fanatically praising Faceas Clay.
** Vice-Director Matic in the final chapter. Ever the SmugSnake, Matic corners an exhausted Hiryu after he murdered Clay (as he wanted), explains to him all his plans to take over both the Striders and Enteprise, and is about to execute Hiryu when Cain comes to the rescue. From there, it's all downhill for him: [[spoiler:he fights an injured and weakened Hiryu, but backs away when Hiryu [[{{Determinator}} adamantly refuses to go down]], then finds the Striders he thought were his lackeys don't follow his orders, and then Director Kuramoto (who he ordered his execution) was not only alive, but on to his treason. Cornered, he breaks down and threatens all present with a bomb, only to be ImpaledWithExtremePrejudice seconds after by the main Zain computer he desired for so long.]]
* Nazi soldier Adolf Kaufmann, among all his nasty deeds, spends almost the entirety of ''{{Manga/Adolf}}'' looking for the documents that prove Hitler's Jewish origins in order to destroy them. When he finally succeeds in finding them, he is immediately informed of Germany's defeat and Hitler's death. Having realized that he lost a good chunk of his life in going after what are now useless pieces of paper, he starts laughing madly and then desperately crying.
* In ''Anime/KillLaKill'', Nui Harime completely loses her fake cheery exterior once [[spoiler:Ryuko slices off her arms and Senketsu absorbs them,]] going into a MadnessMantra until [[spoiler: Rei Hououmaru rescues her. [[ComplainingAboutRescuesTheyDontLike Nui then rages her frustrations at her for picking her up]], all while [[HighPressureBlood her now-stubby arms spray blood in her face.]]]] From then on, her bubbly, happy smile is permanently replaced with a SlasherSmile.
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