As of 2010, the latest of the ''VideoGame/MegaManClassic'' series.

In the year 20XX, an outbreak of a robotic-virus known as the "Roboenza" runs rampant across the globe. Roll becomes infected with the virus, and the situation becomes worse as time passes and a cure is not found. Several robots become berserk and attack the city. One day, Dr. Wily appears in Dr. Light's lab with his capsule damaged and asks for help. Mega Man saves Wily from crashing and Wily says that Roboenza-infected robots attacked his spaceship and stole the parts of a medicine-making machine he had been working on to cure the virus. Mega Man agrees to retrieve the stolen parts from the eight Robot Masters. Before he begins, Proto Man arrives to help Mega Man, believing the job to be too big for just one of them, and the two join forces to acquire the cure. Meanwhile, Bass sets out on his own to challenge these new robots.

Robot Masters:
* DWN-073: Blade Man, weak to Commando Bomb, gives [[ThrowingYourSwordAlwaysWorks Triple Blade]]
* DWN-074: Pump Man, weak to Thunder Wool, gives [[MakingASplash Water]] [[LuckilyMyShieldWillProtectMe Shield]]
* DWN-075: Commando Man, weak to Wheel Cutter, gives [[HavingABlast Commando Bomb]]
* DWN-076: Chill Man, weak to Solar Blaze, gives [[AnIcePerson Chill]] [[SpikesOfDoom Spike]]
* DWN-077: Sheep Man, weak to Rebound Striker, gives [[ShockAndAwe Thunder Wool]]
* DWN-078: Strike Man, weak to Triple Blade, gives the [[HyperDestructiveBouncingBall Rebound Striker]]
* DWN-079: Nitro Man, weak to Chill Spike, gives the [[SpikedWheels Wheel Cutter]]
* DWN-080: Solar Man, weak to Water Shield, gives [[ThePowerOfTheSun Solar Blaze]]

[[IThoughtThatWas Do NOT confuse this with]] ''VideoGame/MegaManX'', which came out well before this game.
----
!!Tropes:

* AnnualTitle: ''Mega Man 10'' was coincidentally (?) released in 2010.
* AthleticArenaLevel: Strike Man's stage.
* BeTheBall: Strike Man.
* BigFancyCastle: Blade Man's stage. Bonus points for having enemy castles INSIDE the castle.
* BonusBoss: The Mega Man Killers. Not only that, but if you defeat them, Mega Man can use their weapons in the main game (sadly, Proto Man and Bass cannot).
* CallBack: The SequentialBoss of the first Wily level is [[spoiler:a series of capsules containing the powers of various robot masters from ''1''-''9''; [[VideoGame/MegaMan1 Elec Man]], [[VideoGame/MegaMan2 Wood Man]], [[VideoGame/MegaMan3 Gemini Man]], [[VideoGame/MegaMan4 Ring Man]], [[VideoGame/MegaMan5 Napalm Man]], [[VideoGame/MegaMan6 Flame Man]], [[VideoGame/MegaMan7 Slash Man]], [[VideoGame/MegaMan8 Frost Man]], and [[VideoGame/MegaMan9 Tornado Man]].]]
** Meanwhile, the third fortress boss is [[spoiler:a [[CompositeCharacter cross]] between the familiar Devil series of Wily bosses and the Pico-Pico Master from ''VideoGame/MegaMan2''.]]
* CallForward: It's no secret that Mega Man's storyline eventually leads to VideoGame/MegaManX, where a ''virus'' is causing reploids to go maverick. Sound familiar?
* CeilingCling: Blade Man
* ChekhovsGun: [[spoiler:the prototype cure that Wily gave to Roll.]]
* ContinuityNod: When playing as Proto Man, [[ShopKeeper Auto runs the shop]] wearing a Met Helmet to [[PaperThinDisguise hide his identity]], this is probably the same Met Helmet he tried to offer to Mega Man at the beginning of ''VideoGame/MegaMan7''.
* CoolBike: Nitro Man transforms into one than can drive up walls.
* DownTheDrain: Pump Man's stage. ''Someone'' has to take care of the sewage...
* DualBoss: Suzak and Fenix in Solar Man's stage are Dual {{Mini Boss}}es.
** [[spoiler:SpotTheImpostor: the FinalBoss, where there are two Wily Capsules, one piloted by the real Wily and the other a decoy. The decoy is easy to tell apart by its appearance alone. More subtly, the real Wily would occasionally sneeze (following up from a cutscene before the Wily stages, where Wily sneezes upon signing off his announcement).]]
* {{Expy}}: Suzak and Fenix are pretty much flying versions of Heat Man, having roughly the same attacks.
* FireIceLightning: Solar Man, Chill Man, Sheep Man, respectively.
* GarnishingTheStory: The Wily Machine of this game sports a pirate hat, for no other reason than RuleOfCool.
* GiantEnemyCrab: Crab Puncher, the second fortress boss.
* GretzkyHasTheBall: Strike Man's level; a baseball-themed robot master, with stage enemies that utilize soccer balls and footballs as well.
* IcePalace: Chill Man's stage switches between this and SlippySlideyIceWorld at various points.
* IllGirl: In the game's intro, Roll ends up ill because she gets Roboenza.
* LegacyBossBattle: you get to fight the "[[VideoGame/MegaManDrWilysRevenge Mega]] [[VideoGame/MegaManIII Man]] [[VideoGame/MegaManIV Killers]]" as DLC stages.
* MesACrowd: An otherwise-weak enemy (Yonbain) in Solar Man's stage will do this if you don't kill it quickly.
* MythologyGag: There was also a Blade Man in the infamous ''[[CanonDiscontinuity Mega Man 3]]'' (DOS) for the PC. Even more amusing, that Blade Man's signature weapon, the Blade Launcher, also launched a SpreadShot of three blades, similar to the Triple Blade. Even ''more'' amusing is that both Blade "Men" have purple as their dominant color.
* OneWheeledWonder: Sepa Roader
* OverlyLongGag: [[spoiler:Mega Man's upwards trip towards Wily's SpaceStation.]]
* PinballProjectile: Strike Man's Rebound Striker qualifies- on the third bounce, it heads directly for Mega Man.
* PlayerGuidedMissile: The Commando Bomb can change directions in mid-air by pressing the appropriate direction (up, down, left, or right) after firing it.
* PopTheTires: The reasoning behind Nitro Man's weakness against the Chill Spike.
* PromotedToPlayable: Proto Man is playable from the start this time, unlike ''VideoGame/MegaMan9''; this time, Bass, who was curiously absent in ''9'', is available via DLC. He plays virtually identical to how he did in ''VideoGame/MegaManAndBass'', only without the double-jump.
** Bass wasn't completely gone from ''9''; he [[http://images1.wikia.nocookie.net/__cb20090423135039/megaman/images/0/0b/8-bitBass.png appears]] in the ending. Additionally, WordOfGod has it that Bass was [[http://www.rockmancorner.com/2008/11/fortes-abscence-in-rm9-officially.html undergoing adjustments]] at the time, possibly hinting to his DLC appearance in the next title.
* ReverseShrapnel: The Water Shield, when fired out.
* SaveTheVillain: In the ending, when Mega Man discovers that [[spoiler: Dr. Wily has become very sick himself, he decides right then and there to take him to a hospital. In apparent gratitude, Wily leaves behind enough antidote to cure the Roboenza outbreak when he makes his escape]].
* ShoutOut:
** Sheep Man and his electric based powers, as well as his stage, are a reference to Literature/DoAndroidsDreamOfElectricSheep, of which Film/BladeRunner was adapted from.
** Blade Man's mini-boss is a small castle which, upon defeat, hoists up a white flag in surrender. [[VideoGame/SuperMarioBros1 A certain Italian plumber did that whenever he conquered castles too...]]
*** Blade Man himself resembles Guiron, one of {{Gamera}}'s opponents.
* SpreadShot: '''Triple''' Blade.
* StealthPun: Strike Man's weakness is the Triple Blade. Three strikes and you're out?
* TransformingMecha: Nitro Man can transform into a motorbike.
* UtilityWeapon: Nitro Man's Wheel Cutter can be used to climb walls.
* WhiteFlag: After defeating the Tricastle, it will humorously raise a white flag. Then it explodes.
* [[spoiler: [[BatmanCanBreatheInSpace Wily Can Breathe In Space]]: Averted after the final battle. Where he catches influenza.]]
----